| DJ Twenty-One Transport Ltd | Administrative & support | 2025 |
| DJC Vehicles 4 U Ltd | Wholesale & retail | 2023 |
| DJM 95 Ltd | Financial services | 2022 |
| DJR Steam Boiler Engineering Ltd | Manufacturing | 2025 |
| Djrc Medical Ltd | Health & social care | 2022 |
| Djtengineering Limited | Professional & scientific | 2011 |
| DK Group Investments Ltd. | Professional & scientific | 1983 |
| DK Packing & Casemaking Limited | Administrative & support | 1984 |
| DK Property Portfolio Limited | Real estate | 2018 |
| DKG Moto Limited | Wholesale & retail | 2015 |
| DKL Engineering Group Ltd | Manufacturing | 2022 |
| DLM Consultancy Services Ltd | Professional & scientific | 2025 |
| DM (Central) Ltd | Transport & logistics | 2026 |
| DM Payroll Solutions Limited | Information & communication | 2019 |
| DMA Horse Transport Limited | Other services | 2014 |
| DMP Properties Ltd | Households | 2021 |
| DNA Apparel Limited | Wholesale & retail | 2025 |
| DNA Realty Limited | Real estate | 2019 |
| DNG Freight Limited | Transport & logistics | 2025 |
| DNH Fashions Ltd | Wholesale & retail | 2012 |
| DO IT ALL Construction Ltd | Construction | 2024 |
| DO24 Group Ltd | Transport & logistics | 2023 |
| Doai Limited | Information & communication | 2019 |
| Doctoral Tutors Limited | Education | 2017 |
| Doda Limited | Construction | 2026 |
| Dogstar Holdings Limited | Financial services | 2017 |
| Dogstar Medical Limited | Professional & scientific | 2012 |
| Dogstar Technologies Limited | Professional & scientific | 2019 |
| Doit Technologies Ltd | Information & communication | 2024 |
| Dolf Consulting Ltd | Professional & scientific | 2025 |
| Dolinschi Ltd | Transport & logistics | 2025 |
| Dollies at BKS Ltd | Other services | 2019 |
| Dolly Premium Ltd | Health & social care | 2014 |
| Doman Web Design Studio Ltd | Wholesale & retail | 2020 |
| Domestic Abuse Support Hub CIC | Education | 2025 |
| Dominic Frazer Ltd | Wholesale & retail | 2023 |
| Dominion Lawn Ltd | Administrative & support | 2025 |
| DON Willis Management Limited | Real estate | 1974 |
| Don'T Waste Time Ltd | Transport & logistics | 2021 |
| Donadi Ltd | Transport & logistics | 2021 |
| Door Monitoring Systems Ltd | Manufacturing | 2026 |
| Doors and Drawers Limited | Construction | 2019 |
| Doorsopen Marketing Ltd | Professional & scientific | 2007 |
| Dorin Rosca Ltd | Transport & logistics | 2016 |
| DOT Cargo Ltd | Transport & logistics | 2026 |
| Dots Education Ltd | Education | 2024 |
| Double C Export Ltd | Transport & logistics | 2024 |
| Double Happiness Limited | Hospitality | 2026 |
| Double MM Trading Ltd | Wholesale & retail | 2018 |
| Double Tyres Ltd | Wholesale & retail | 2025 |
| Douglass Motors (Dorset) Limited | Wholesale & retail | 2012 |
| Douglass Motors Limited | Wholesale & retail | 2001 |
| Dougwinder Ltd | Arts & recreation | 2019 |
| Douro Transport Limited | Transport & logistics | 2017 |
| DP 2000 Sheet Metal Ltd | Manufacturing | 2001 |
| DPF Clean Team Limited | Wholesale & retail | 2014 |
| DPH Catering Limited | Hospitality | 2024 |
| DR C D Sutton Ltd | Health & social care | 2013 |
| DR Debashis Biswas Limited | Health & social care | 2016 |
| DR E D Epurescu Limited | Health & social care | 2016 |
| DR F Hussain Ltd | Health & social care | 2025 |
| DR Hadeel Ltd | Real estate | 2025 |
| DR James Bennett Limited | Health & social care | 2008 |
| DR K C Mildwaters Consulting LLP | | 2006 |
| DR Maganga Medical Services Ltd | Health & social care | 2013 |
| DR Rahul Ltd | Education | 2024 |
| DR Sotayo Limited | Information & communication | 2023 |
| DR Sundus Limited | Real estate | 2022 |
| DR ZOE Healthcare Ltd | Wholesale & retail | 2020 |
| Dragon Waste Limited | Other services | 1992 |
| Dragonfly Aviation Services Limited | Transport & logistics | 2012 |
| Dragons Papercraft Limited | Wholesale & retail | 2012 |
| Draica Toma Haulage Limited | Transport & logistics | 2018 |
| Drain Clearance & Repairs Limited | Water & waste | 2003 |
| Draper Civil Engineering Limited | Construction | 2001 |
| Draper Hinks Limited | Professional & scientific | 2018 |
| Drarangedara Ltd | Health & social care | 2022 |
| Draycote Consulting Limited | Construction | 2017 |
| Draycote Grange Management Company Limited | Households | 2014 |
| Draycote Water Sailing Club Limited (the) | Arts & recreation | 1970 |
| Drayton Park Road (184) Freehold Limited | Households | 2016 |
| Dreamsoft Technologies Limited | Information & communication | 2021 |
| Dressage UK Limited | Extraterritorial | 2010 |
| Drew Projects Ltd | Professional & scientific | 2025 |
| Driveplan Motor Finance Solutions Limited | Financial services | 2024 |
| Driver Nicolae Chetraru Ltd | Transport & logistics | 2017 |
| Drivestruct Analytics Ltd | Professional & scientific | 2025 |
| Droneswarm Limited | Extraterritorial | 2006 |
| Drumea Transport Ltd | Transport & logistics | 2025 |
| Drury Lane Management Limited | Real estate | 2017 |
| DS Architecture Studio Ltd | Professional & scientific | 2025 |
| DSD Deliver Limited | Transport & logistics | 2024 |
| DSF Transport Ltd | Transport & logistics | 2018 |
| DSG Imprint Ltd | Construction | 2015 |
| DSK & M Builders Ltd | Construction | 2018 |
| DSK Plumbing and Property Services Ltd | Water & waste | 2021 |
| Dsrugby Ltd | Education | 2021 |
| Dsss Properties Ltd | Real estate | 2022 |
| DT Europe Limited | Transport & logistics | 2012 |
| DT Morris Holdings I Limited | Financial services | 2025 |