| Cambridge Advanced Machining Limited | Extraterritorial | 2016 |
| Cambridge Applied Technologies Limited | Information & communication | 2025 |
| Cambridge Building Surveyors Ltd | Professional & scientific | 2019 |
| Cambridge Centre for Applied Research in Human Trafficking CIC | Information & communication | 2018 |
| Cambridge Christmas Parties Limited | Hospitality | 2024 |
| Cambridge Clinical Courses Limited | Education | 2021 |
| Cambridge Commercials Limited | Wholesale & retail | 2023 |
| Cambridge Corals Limited | Agriculture & fishing | 2026 |
| Cambridge Direction Limited | Professional & scientific | 2011 |
| Cambridge Fine Instruments Limited | Professional & scientific | 2026 |
| Cambridge Gardening School Ltd | Education | 2025 |
| Cambridge Glassblowing Limited | Administrative & support | 1991 |
| Cambridge Haematology Limited | Health & social care | 2020 |
| Cambridge Househunt Limited | Real estate | 2003 |
| Cambridge Ideas Network Limited | Professional & scientific | 2017 |
| Cambridge Indigo Ltd | Hospitality | 2024 |
| Cambridge Innovateai Ltd | Professional & scientific | 2024 |
| Cambridge Land Ltd | Real estate | 2009 |
| Cambridge Marquees & Luxury Toilets Limited | Arts & recreation | 2019 |
| Cambridge Microconsulting Limited | Information & communication | 2018 |
| Cambridge Motorworks Limited | Wholesale & retail | 2010 |
| Cambridge Pixel EOT Limited | Administrative & support | 2020 |
| Cambridge Pixel Ltd | Information & communication | 2007 |
| Cambridge Process Engineering Limited | Professional & scientific | 2025 |
| Cambridge Relocations Limited | Extraterritorial | 2012 |
| Cambridge Sensor Innovation Limited | Manufacturing | 2015 |
| Cambridge Technology Innovations Limited | Professional & scientific | 2011 |
| Cambridge Window Cleaning Ltd | Administrative & support | 2018 |
| Cambridge Wine Limited | Wholesale & retail | 2003 |
| Cambridge Xray Systems Limited | Professional & scientific | 2012 |
| Cambridgeshire Glamping Ltd | Hospitality | 2023 |
| Cambs Digitise Ltd | Information & communication | 2025 |
| Cambs Gritting Ltd | Transport & logistics | 2020 |
| Camcore Property Development Ltd | Construction | 2022 |
| Camgenomics Ltd | Professional & scientific | 2013 |
| Cammak Estates Limited | Financial services | 2017 |
| Cammak Property Management Limited | Real estate | 2017 |
| Campbell Highways Limited | Construction | 2025 |
| Camprop Construction Limited | Construction | 2018 |
| Camrend Ltd | Construction | 2018 |
| Canary & Co Creative Consultants Limited | Professional & scientific | 2024 |
| Cantab PI Limited | Professional & scientific | 2020 |
| Canter Animal Health Limited | Professional & scientific | 2019 |
| Capay Audio Ltd | Arts & recreation | 2021 |
| Capela Ltd | Administrative & support | 2003 |
| Captech Compliance Limited | Administrative & support | 2025 |
| Car Trade (Cambridge) Limited | Wholesale & retail | 2005 |
| Carbyne Consultancy Ltd | Professional & scientific | 2017 |
| Cardon Rettie Ltd | Professional & scientific | 2025 |
| Care Choices Ltd | Information & communication | 1992 |
| Carewise AI Limited | Information & communication | 2026 |
| Carl LEE & Sons Limited | Agriculture & fishing | 1949 |
| Caroflow Limited | Construction | 1992 |
| Carolan Davidge Limited | Professional & scientific | 2020 |
| Carosystems Limited | Construction | 1985 |
| Carrington Court Royston Management Limited | Households | 2006 |
| Carter Properties Limited | Real estate | 2002 |
| Carter Recruitment Limited | Administrative & support | 2015 |
| Cartezia Cambridge Limited | Professional & scientific | 2006 |
| Casablanca Pizzeria Ltd | Hospitality | 2024 |
| Case Estates Limited | Construction | 2016 |
| Cataleyes Ltd | Professional & scientific | 2023 |
| Catalysis Management Ltd | Extraterritorial | 2002 |
| Cater-Hire Limited | Administrative & support | 1997 |
| Catering by Paulo Ltd | Other services | 2017 |
| Catojoza Limited | Information & communication | 2018 |
| CB Architect Royston Ltd | Professional & scientific | 2021 |
| CB Catering Group Ltd | Hospitality | 2025 |
| CC Growth Limited | Education | 2026 |
| Cdhd Holdings Limited | Financial services | 2021 |
| Celia Matsanga Ltd | Extraterritorial | 2018 |
| CELL4FOOD UK Ltd | Professional & scientific | 2026 |
| Cencroft Limited | Other services | 2026 |
| Central Rider Training Ltd | Education | 2012 |
| Century Innovations Asset Management Ltd | Financial services | 2020 |
| Century Innovations Ltd | Information & communication | 2011 |
| Certax Accounting (N Herts) Limited | Professional & scientific | 2008 |
| Cfdp Consulting Limited | Information & communication | 2025 |
| CGN Investments Ltd | Financial services | 2019 |
| CGN Properties Ltd | Real estate | 2019 |
| Chalfont Refrigeration Services Limited | Manufacturing | 2003 |
| Chalid Construction Recruitment Ltd | Administrative & support | 2022 |
| Change Revolution Ltd | Education | 2008 |
| Changi Ltd | Professional & scientific | 2023 |
| Channing Pearson Electrical Contractors Ltd | Construction | 2021 |
| Chantal Lipscombe Art Ltd | Arts & recreation | 2024 |
| Chapman Construction Services Limited | Construction | 1998 |
| Chargestream Limited | Information & communication | 2026 |
| Charles Owen Bespoke Ltd | Manufacturing | 2024 |
| Charlotte Rous Communications Limited | Professional & scientific | 2022 |
| Chawfine Shipping & Removal Services Ltd | Water & waste | 2026 |
| Cheap Storage (Greenlow) Limited | Transport & logistics | 2022 |
| Cheap Storage (R&T) Limited | Transport & logistics | 2025 |
| Cheap Storage Limited | Transport & logistics | 2003 |
| Chear Ltd | Health & social care | 2005 |
| Chear Products Limited | Health & social care | 2020 |
| Cheeretrading Limited | Professional & scientific | 2019 |
| Chen Smith Limited | Hospitality | 2021 |
| Cherry Wood Construction Limited | Construction | 2020 |
| Chesterton Mews Limited | Construction | 2020 |