| RB & E Ltd | Wholesale & retail | 2022 |
| Redcity Ltd | Information & communication | 2014 |
| Retrofit Energy Ltd | Information & communication | 2022 |
| REX Build Limited | Construction | 2022 |
| RGS Landscaping Specialists Ltd | Administrative & support | 2022 |
| Ripleys of Southport Ltd | Hospitality | 2019 |
| Risk Tailors Limited | Financial services | 2020 |
| Rjsg Limited | Professional & scientific | 2014 |
| RK Catering Solutions Ltd | Hospitality | 2024 |
| Rkash Associates Limited | Information & communication | 2013 |
| Rmor Advisory Ltd. | Professional & scientific | 2014 |
| Road 2 Change Coaching Limited | Health & social care | 2018 |
| ROB J Ltd | Information & communication | 2014 |
| Robert Welburn Construction Ltd | Construction | 2015 |
| Rockfen Limited | Information & communication | 2018 |
| Roman House Improvements Limited | Construction | 2021 |
| Romanow Consulting Services Ltd. | Information & communication | 2017 |
| Rosebush Holdings Limited | Financial services | 2023 |
| Route J.Tu-B Limited | Transport & logistics | 2014 |
| Rovereng Limited | Manufacturing | 2016 |
| Rowley IT Limited | Information & communication | 2016 |
| Rubicon Enterprise Limited | Information & communication | 2010 |
| Rumours SW Limited | Hospitality | 2014 |
| S M Hammond Ltd | Information & communication | 2011 |
| S R Forsyth (Bristol) Ltd | Administrative & support | 2009 |
| S6 Wraps Training Limited | Education | 2019 |
| Sachi PVT Ltd | Information & communication | 2016 |
| Saffron Sales and Marketing Limited | Administrative & support | 2016 |
| SAL Packaging Ltd | Wholesale & retail | 2006 |
| Salisbury Mill Ltd | Hospitality | 2024 |
| Saltworks Supply Company Limited | Manufacturing | 2016 |
| Samba & Mela Ltd | Information & communication | 2017 |
| Samkyaan Limited | Information & communication | 2014 |
| SAN Giuseppe Pizzeria Limited | Hospitality | 2017 |
| Sankofa Solutions Ltd | Information & communication | 2021 |
| Sapien Living Ltd | Construction | 2017 |
| Save More Superstore Hayes Ltd | Wholesale & retail | 2012 |
| SCL Media Limited | Wholesale & retail | 2006 |
| Sean Webb Limited | Information & communication | 2015 |
| Section:Media Ltd | Administrative & support | 2009 |
| Semmika Ltd | Administrative & support | 2014 |
| Senity Solutions Ltd | Information & communication | 2016 |
| Sergei Ltd | Information & communication | 2012 |
| Shawma E-Commerce Solutions Limited | Information & communication | 2010 |
| Sherlock Safety Services Ltd | Information & communication | 2019 |
| Shoe LAB Limited | Wholesale & retail | 2019 |
| Shutter Wize Ltd | Manufacturing | 2019 |
| Siass Ltd | Hospitality | 2022 |
| Simdata I T Limited | Information & communication | 2016 |
| Siwel Telecommunications Limited | Information & communication | 2016 |
| Skye Solutions Recruitment Limited | Administrative & support | 2016 |
| Smart Build Electrical Contractors Ltd | Construction | 2021 |
| Smart Mason Limited | Construction | 2011 |
| Smart People Training & Development Company Ltd | Administrative & support | 2010 |
| Smersh Consulting Ltd | Professional & scientific | 2015 |
| Snapos Real-Estate Limited | Real estate | 2017 |
| SO Associates Ltd | Professional & scientific | 2018 |
| Solway Sunset Tanning Salon Limited | Other services | 2017 |
| Soussi Connect Ltd | Information & communication | 2016 |
| South West Autoworx Ltd | Wholesale & retail | 2019 |
| Southall Quality Food Ltd | Wholesale & retail | 2018 |
| Southdown Building & Plumbing Ltd | Construction | 2023 |
| Sparrow Construction Contracting Limited | Construction | 2019 |
| Spear Recruitment Ltd | Administrative & support | 2011 |
| Specialist Rigging Services Limited | Administrative & support | 2000 |
| Speed Steel Industries Ltd | Manufacturing | 2019 |
| Spice RAJ of Stone Ltd | Hospitality | 2019 |
| Springfield Contract Services Limited | Professional & scientific | 2011 |
| SR Motor Body Repairers Ltd | Wholesale & retail | 2013 |
| ST. Anne's Stay & Play Limited | Health & social care | 1999 |
| Stark Brickwork Services Ltd | Construction | 2016 |
| Steel Design Ltd | Professional & scientific | 2023 |
| Stenze Ltd | Manufacturing | 2019 |
| Sterling Financial Consulting Ltd | Information & communication | 2017 |
| Stimson Barfield Limited | Hospitality | 2003 |
| Stingray Media Limited | Information & communication | 2023 |
| Strawberry Sage Limited | Administrative & support | 2019 |
| Streetvibe Young Peoples Services (Syps) Limited | Health & social care | 2008 |
| Studio 73 Limited | Wholesale & retail | 2013 |
| Stusys Consult Limited | Information & communication | 2014 |
| Suchworks Ltd | Information & communication | 2007 |
| Suco Solutions Ltd | Information & communication | 2016 |
| Sundial Inn LLP | | 2020 |
| Sungrundorn Group Ltd | Hospitality | 2014 |
| Sussex Bakes Ltd | Wholesale & retail | 2017 |
| Sussex Garden Builds Ltd | Construction | 2021 |
| Sutherland Prosperity Limited | Financial services | 2019 |
| Swan River Ltd | Administrative & support | 2023 |
| Sykes Cleaning Group Limited | Administrative & support | 2021 |
| Syncsense Limited | Administrative & support | 2021 |
| Synergy Vehicle Parts Ltd | Wholesale & retail | 2021 |
| SZ IT Services Ltd | Information & communication | 2016 |
| T&S Plant Hire Limited | Construction | 2022 |
| TAP 'N' Shower UK Limited | Wholesale & retail | 2016 |
| Taste Menu Limited | Hospitality | 2014 |
| Tasty Hot Food Limited | Hospitality | 2018 |
| Teak Interiors Ltd | Construction | 2023 |
| Tewitfield Inns Ltd | Hospitality | 2024 |
| THE Bees Knees (Rustington) Limited | Health & social care | 2016 |
| THE Car Section Ltd | Wholesale & retail | 2020 |