| Salnaz Global Ltd | Administrative & support | 2026 |
| Salon Beaut Ltd | Other services | 2019 |
| Sangha Newsagents Ltd | Wholesale & retail | 2008 |
| Sanots Logistics Ltd | Transport & logistics | 2022 |
| Sapper International Ltd | Wholesale & retail | 2018 |
| Savva Technical Ltd | Construction | 2021 |
| SAW Logistics Ltd | Wholesale & retail | 2023 |
| Scarlett & Guest Building Services Limited | Construction | 2006 |
| Scott Quantity Surveying Ltd | Professional & scientific | 2019 |
| Scunny Hands Car Wash Ltd | Wholesale & retail | 2026 |
| Searched Enterprises Limited | Professional & scientific | 2025 |
| Sedgley Interiors Ltd | Professional & scientific | 2025 |
| Seero Limited | Wholesale & retail | 2024 |
| Select Organic Ltd | Hospitality | 2018 |
| Sell Your Ride Ltd | Wholesale & retail | 2023 |
| Sembhi Estates Ltd | Real estate | 2026 |
| Sentinel Force Ltd | Administrative & support | 2023 |
| Sentralink Limited | Wholesale & retail | 2025 |
| Sfprotection Ltd | Public administration | 2020 |
| SG Finconsulting Ltd | Professional & scientific | 2024 |
| SH Motors(Uk) Ltd | Wholesale & retail | 2023 |
| Shadow to Spotlight Coaching Ltd | Education | 2026 |
| Shafe Company Ltd | Health & social care | 2013 |
| Shakespeares Inn Ltd | Hospitality | 2025 |
| Shammah Motors Ltd. | Wholesale & retail | 2016 |
| Shanamms Healthcare Limited | Health & social care | 2014 |
| Shanz Services Limited | Manufacturing | 2013 |
| Sharpix Ltd | Wholesale & retail | 2025 |
| Shehry's Construction Ltd | Construction | 2022 |
| Sheratan Ltd | Information & communication | 2018 |
| Shiven Property Ltd | Real estate | 2024 |
| Shri Pashupatinath Mandir of UK | Other services | 2014 |
| Sikhouse Investments Ltd | Financial services | 2020 |
| Silvo Enterprises Ltd | Wholesale & retail | 2023 |
| Sinclair Storage Systems Limited | Construction | 2007 |
| Singh & Kaur Investment Properties Ltd | Real estate | 2024 |
| Sinnamma Ltd | Wholesale & retail | 2019 |
| Sirius Online Ltd | Education | 2025 |
| Skin and YOU Ltd | Health & social care | 2025 |
| SL Claddingpower Ltd | Construction | 2024 |
| Smart World Birmingham Limited | Other services | 2022 |
| SMT Building Solutions Ltd | Construction | 2021 |
| Sohal Takeaway Ltd | Hospitality | 2025 |
| Solarvolt Ltd | Manufacturing | 2026 |
| Somtreangel Limited | Health & social care | 2022 |
| Sourcing Property Solutions Ltd | Real estate | 2026 |
| Sparta Customs Ltd | Professional & scientific | 2026 |
| Sparta Signage Limited | Manufacturing | 2022 |
| Speakup Challenge Ltd | Professional & scientific | 2017 |
| Speakup International Ltd | Professional & scientific | 2022 |
| Specialist Gastroenterology Consultancy Ltd | Health & social care | 2021 |
| Spence Building Services Ltd | Construction | 2017 |
| Spesco Ltd | Information & communication | 2016 |
| Spinners Laundry Services Ltd | Other services | 2025 |
| Spring Arts CIC | Education | 2023 |
| Spring Global Limited | Wholesale & retail | 2015 |
| Spring Gutter Limited | Health & social care | 2024 |
| Springfield Social Club U.K Limited | Hospitality | 2020 |
| SPS Rate Mark Ltd | Wholesale & retail | 2016 |
| SRI Property Ltd | Other services | 2017 |
| SSB Haulage Company Limited | Transport & logistics | 2011 |
| ST Marys Medics Ltd | Health & social care | 2013 |
| ST. Ambrose Properties Limited | Real estate | 2009 |
| Staffing Manners Ltd | Administrative & support | 2026 |
| Star Auto Recovery (Blackheath) Limited | Transport & logistics | 1979 |
| Star CWS Ltd | Professional & scientific | 2018 |
| Star News (Portway Road) Limited | Wholesale & retail | 2026 |
| Starvalley Bar & Restaurant Limited | Hospitality | 2023 |
| Station Road Tyre Centre Ltd | Wholesale & retail | 2022 |
| Stebro Flooring Company Limited | Construction | 1964 |
| Stephen M Godber Funerals Limited | Extraterritorial | 1988 |
| Stiled Home Improvements Limited | Construction | 2011 |
| Stime Group Ltd | Real estate | 2025 |
| Stoic Events Company Ltd | Arts & recreation | 2021 |
| Storm Industries Limited | Information & communication | 2016 |
| Stourbridge Skip Hire Limited | Water & waste | 2018 |
| Strathmore Labs Ltd | Information & communication | 2015 |
| Stream Investment Properties Limited | Real estate | 2022 |
| Structural Modelling Limited | Construction | 2021 |
| Stsa Trading Ltd | Hospitality | 2022 |
| Stuffed ANY Way YOU Like Limited | Hospitality | 2022 |
| Success Business and Leadership Academy Ltd | Administrative & support | 2023 |
| Sudhan Logistics Ltd | Transport & logistics | 2024 |
| Sudharas Ltd | Arts & recreation | 2026 |
| Sugar ME UP! Ltd | Wholesale & retail | 2023 |
| Sukhdev Transport Limited | Transport & logistics | 2018 |
| Sukhjit Transport Limited | Transport & logistics | 2011 |
| Sunriz Ltd | Wholesale & retail | 2025 |
| Superb Logistics Ltd | Transport & logistics | 2022 |
| SW2026 Ltd | Real estate | 2026 |
| Swadisht Limited | Hospitality | 2018 |
| Swami Shreeji Ltd | Wholesale & retail | 2014 |
| SX Partners Ltd | Administrative & support | 2026 |
| Synthetico Ltd | Professional & scientific | 2026 |
| Synthiana Limited | Health & social care | 2023 |
| Szetech Limited | Information & communication | 2009 |
| Szymon Smagala Transport Ltd | Transport & logistics | 2021 |
| T&O Ventures Ltd | Other services | 2022 |
| Table Manner RP Ltd | Hospitality | 2025 |
| Tamim Yusuf Limited | Hospitality | 2026 |