| 10-16 Deans Close Whickham Limited | Households | 2009 |
| 15 Eslington Terrace Limited | Households | 2001 |
| 3PCUBED Ltd | Professional & scientific | 2020 |
| 42 Holdings Limited | Construction | 2018 |
| ABM Medical Ltd | Health & social care | 2022 |
| AC Supplies Ltd | Manufacturing | 2013 |
| Admire Retail Limited | Wholesale & retail | 2025 |
| AGM Print Maintenance Limited | Manufacturing | 2003 |
| AK Automotive Recycling Ltd | Wholesale & retail | 2024 |
| AK Quality Solutions Ltd | Public administration | 2019 |
| Alan Jordan Reflex Ltd | Wholesale & retail | 2023 |
| Almb Investments Ltd | Other services | 2014 |
| Amore Pizza & Deserts Ltd | Hospitality | 2024 |
| Annular Limited | Hospitality | 2004 |
| Asbo Interactive Limited | Information & communication | 2016 |
| Atlas Investment Holdings Ltd | Real estate | 2025 |
| Ayma Engineering Services Ltd | Professional & scientific | 2026 |
| Barely Blushed Studio Limited | Other services | 2025 |
| Beechwood Living Limited | Real estate | 2016 |
| Beespoke Protection Ltd | Manufacturing | 2025 |
| Blue Barns Poultry Farms Limited | Agriculture & fishing | 2010 |
| Blue Barns Pullet Rearing Limited | Agriculture & fishing | 2022 |
| Blue Potion Games Limited | Information & communication | 2016 |
| Bluemoon Auto Gallery Ltd | Transport & logistics | 2025 |
| Bluexiii Biotech Limited | Arts & recreation | 2026 |
| Boysenberry Ltd | Construction | 2017 |
| Bringing Words to Life Limited | Education | 2013 |
| Brown Developments Limited | Real estate | 2016 |
| Budget Workspace Holdings Limited | Financial services | 2015 |
| Budget Workspace Limited | Real estate | 1997 |
| Bwtl CIC | Education | 2014 |
| CA Academy Events CIC | Other services | 2025 |
| CA Beauty Academy Ltd | Other services | 2019 |
| Candun Solutions Ltd | Information & communication | 2025 |
| Cannapharma Ltd | Manufacturing | 2024 |
| Carers Trust Tyne & Wear | Other services | 1996 |
| Cedarwood Interiors Ltd | Construction | 2020 |
| Champagne Entertainments Ltd | Arts & recreation | 2023 |
| Cobbroxpizza Limited | Extraterritorial | 2021 |
| Collins Accountancy Ltd | Professional & scientific | 2010 |
| Colour Connections (NE) Community Interest Company | Health & social care | 2024 |
| Compass Control Solutions Ltd | Professional & scientific | 2024 |
| Connected Community CIC | Real estate | 2020 |
| Crebiliti Ltd | Information & communication | 2025 |
| Crossman Timber Ltd | Agriculture & fishing | 2017 |
| Darke Creative Limited | Professional & scientific | 2022 |
| DCA Electrical Solutions Limited | Construction | 2015 |
| Decomm Offshore Limited | Construction | 2016 |
| Delis Dmello Consultant Ltd | Administrative & support | 2024 |
| Dental Equipment Repair Services Limited | Manufacturing | 2003 |
| Derwent Park Caravan Site Ltd | Hospitality | 2018 |
| Derwent Valley Accountancy Ltd | Professional & scientific | 2026 |
| Derwent Valley Caravans Ltd | Wholesale & retail | 2019 |
| Derwent Valley Ecology Ltd | Professional & scientific | 2022 |
| Derwentside Property Co. Limited | Real estate | 2000 |
| Devine Light Production Ltd | Professional & scientific | 2011 |
| DHF Products Ltd | Manufacturing | 2010 |
| Digital Bridge Community CIC | Information & communication | 2026 |
| Digital Pest Solutions Ltd | Transport & logistics | 2022 |
| Dipwood Enterprises LLP | | 2011 |
| DJ Service and Repair Ltd | Wholesale & retail | 2026 |
| Doula Support UK CIC | Administrative & support | 2024 |
| Drilling Ltd | Mining & quarrying | 2017 |
| DXD Group Ltd | Information & communication | 2017 |
| Eco Heat Wood Products Ltd | Manufacturing | 2021 |
| Electronic and Semiconductor Failure Analysis Solutions Limited | Professional & scientific | 2025 |
| Elite Property and Facilities Maintenance Ltd | Construction | 2024 |
| Empowered Psychology Limited | Education | 2023 |
| Engage Physiotherapy Ltd | Health & social care | 2023 |
| F.S.G. Engineering Limited | Manufacturing | 2003 |
| Farnell Oral Health Care Limited | Administrative & support | 2008 |
| Fell Farm Court Limited | Administrative & support | 2019 |
| Fishbone Soup Media Ltd | Information & communication | 2025 |
| Flower Design Limited | Wholesale & retail | 2009 |
| Fortis Cura Ltd | Health & social care | 2024 |
| Fortiva Furnishing Ltd | Wholesale & retail | 2026 |
| Friar's Oak Properties Limited | Real estate | 2025 |
| G10 PSV Ltd | Professional & scientific | 2024 |
| G3 Developments Ltd | Construction | 2018 |
| G3 Holdings (NE) Limited | Financial services | 2018 |
| Gaba Supermarket Limited | Wholesale & retail | 2024 |
| Gauri Shankara Ltd | Wholesale & retail | 2025 |
| Gemini Rooms Ltd | Other services | 2025 |
| George M Penrice - Building Consultancy Limited | Professional & scientific | 2022 |
| Glencoe Garage Limited | Wholesale & retail | 2003 |
| GM Paving and Groundwork’S Limited | Construction | 2020 |
| Green-Scope Landscaping Ltd | Agriculture & fishing | 2021 |
| Greenway Integrated Pest Management Ltd | Administrative & support | 2017 |
| Harlo Cars Limited | Wholesale & retail | 2019 |
| Headless Chickens BBQ Ltd | Hospitality | 2026 |
| Helleborus Property Ltd | Construction | 2024 |
| High Spen Consulting Limited | Professional & scientific | 2018 |
| High Spen Social Action CIC | Public administration | 2024 |
| Hobby Horse Academy UK Limited | Other services | 2024 |
| Home of Natural Stone Ltd | Construction | 2010 |
| Homeworx (Rowlands Gill) Limited | Construction | 2008 |
| Hyland PM Limited | Real estate | 2026 |
| I.Parker Electricals Ltd | Construction | 2012 |
| Images Tyne and Wear Limited | Professional & scientific | 2008 |
| Imperium Informatics Ltd | Information & communication | 2011 |