| Stoneview Commercials Ltd | Wholesale & retail | 2002 |
| Stoneview Healthcare Ltd | Wholesale & retail | 2026 |
| Stoneview Residentials Ltd | Real estate | 2014 |
| Stonez Enterprises Ltd | Wholesale & retail | 2022 |
| Storea Ltd | Wholesale & retail | 2019 |
| Stories of Ltd | Other services | 2019 |
| Storybridge Consulting Limited | Professional & scientific | 2024 |
| Stotting Ltd | Financial services | 2021 |
| Stour Lifts Limited | Manufacturing | 2008 |
| STR Clinical Consulting Ltd | Professional & scientific | 2025 |
| Straight Thinkers Limited | Professional & scientific | 2011 |
| Strategic Growth Coaching Ltd | Professional & scientific | 2021 |
| Stratton Property WD Holdings Limited | Real estate | 2021 |
| Strawberry Music Ltd | Wholesale & retail | 2007 |
| Stream Flow Ltd | Wholesale & retail | 2025 |
| Stream of Bytes Ltd | Information & communication | 2023 |
| Streamline Utility Solutions Ltd | Construction | 2025 |
| Strength Positive Limited | Arts & recreation | 2017 |
| Stress Free Delivery Limited | Transport & logistics | 2025 |
| Strider FOX Global Limited | Financial services | 2023 |
| Strive Electrical Ltd | Construction | 2026 |
| Strt Sply Ltd | Wholesale & retail | 2026 |
| Structural Creations Limited | Manufacturing | 2021 |
| Structureclad (Fabrications) Ltd | Construction | 2019 |
| Structureiq Ltd | Education | 2026 |
| Strumskis Holdings Ltd | Real estate | 2025 |
| Stryn Limited | Wholesale & retail | 2025 |
| Sttvin Ltd | Wholesale & retail | 2024 |
| Stuart Gillon Ltd | Manufacturing | 2019 |
| Stuart Mcclarnan Limited | Hospitality | 2010 |
| Studio Bronty Limited | Administrative & support | 2024 |
| Studio F30 Ltd | Professional & scientific | 2021 |
| Studio Puss Puss Limited | Arts & recreation | 2024 |
| Studio Youel Ltd | Professional & scientific | 2020 |
| Stumbledome Ltd | Wholesale & retail | 2019 |
| Styrrup Hall Golf and Country Club Limited | Hospitality | 2008 |
| Styson Construction Limited | Mining & quarrying | 2010 |
| SUB Sahara Holdings Ltd | Wholesale & retail | 2023 |
| Sub-Zero Van Sales Limited | Wholesale & retail | 2007 |
| Subliblanks Limited | Wholesale & retail | 2014 |
| Sublimation Magic Limited | Wholesale & retail | 2024 |
| Substation Mechanical Electrical Services Ltd | Construction | 2024 |
| Subways Stainforth Ltd | Manufacturing | 2022 |
| Sucinaria Ltd | Information & communication | 2014 |
| Sudz Commercial Laundry Ltd | Other services | 2020 |
| Sufficiently Limited | Information & communication | 2021 |
| Sugar Monster Ltd | Wholesale & retail | 2026 |
| Suiso Limited | Energy | 2023 |
| Suitability Clothing and Accessories Ltd | Wholesale & retail | 2017 |
| Suitability Clothing Ltd | Wholesale & retail | 2020 |
| Sulcata Surveying Services Limited | Professional & scientific | 2017 |
| Summer Nails 63 Ltd | Other services | 2025 |
| Summersmith Design Ltd | Real estate | 2014 |
| Summersmith Lettings Ltd | Real estate | 2024 |
| Summersmith Properties Ltd | Real estate | 2019 |
| Summit CAD Services Ltd | Professional & scientific | 2020 |
| Summit Clinical Services Ltd | Health & social care | 2026 |
| Sun City Solarium Home Tanning Limited | Other services | 2021 |
| Sun Goddess Skin Aesthetics Ltd | Other services | 2022 |
| Sun Slide Events Ltd | Other services | 2017 |
| Sunbed Sales and Servicing Limited | Wholesale & retail | 2020 |
| Sundrian Ltd | Information & communication | 2025 |
| Sunpride Services Ltd | Wholesale & retail | 2021 |
| Sunquest Lotions Limited | Other services | 2025 |
| Sunquest Rotherham Ltd | Other services | 2025 |
| Sunrises Holdings Ltd | Wholesale & retail | 2021 |
| Sunsail Ltd | Wholesale & retail | 2020 |
| Sunset Real Estate Ltd | Real estate | 2025 |
| Sunsetclean Limited | Administrative & support | 2020 |
| Sunshine Coast Investments Ltd | Financial services | 2026 |
| Suntan City Rawmarsh Ltd | Other services | 2024 |
| Sunway Leisure Ltd | Wholesale & retail | 2022 |
| Sunway Travel (Coaching) Holdings Limited | Extraterritorial | 2013 |
| Sunwin Services Group (2010) Limited | Administrative & support | 2012 |
| Supa Shine Hand Car Wash Ltd | Other services | 2022 |
| Super Limes Limited | Other services | 1935 |
| Super Mario Landscapes Ltd | Administrative & support | 2025 |
| Super Quick Transport Limited | Transport & logistics | 2025 |
| Super Sudds Ltd | Other services | 2025 |
| Superb Takeaway Ltd | Hospitality | 2014 |
| Supercute Ltd | Wholesale & retail | 2020 |
| Supertech Energy Limited | Administrative & support | 2024 |
| Supervalue Ltd | Wholesale & retail | 2023 |
| Supplemedica Ltd | Wholesale & retail | 2015 |
| Support and Safety Group Services Ltd | Administrative & support | 2024 |
| Support and Safety Ltd | Administrative & support | 2022 |
| Support SY1 Ltd | Hospitality | 2017 |
| Supreme Bike Couriers Ltd | Transport & logistics | 2025 |
| Supreme Grinding Machines Limited | Manufacturing | 2005 |
| Sure Car Sales UK Ltd | Wholesale & retail | 2023 |
| Surefix Roofing Services Limited | Construction | 2023 |
| Surekha Hayes Limited | Financial services | 2021 |
| Suresheds UK Ltd | Manufacturing | 2017 |
| Suretex Limited | Construction | 2016 |
| Suri Property Limited | Real estate | 2018 |
| Sursisst Ltd | Health & social care | 2023 |
| Survivor U.K Limited | Administrative & support | 2011 |
| Susan D Baker Consulting Limited | Health & social care | 2021 |
| Sustainable Aquatics Ltd | Wholesale & retail | 2020 |
| Sustainable Energy Direct Ltd | Professional & scientific | 2026 |