| Elton Property Solutions Ltd | Real estate | 2025 |
| ELU Power Tools Ltd | Extraterritorial | 1983 |
| Elupos Holdings Limited | Hospitality | 2018 |
| Elva Skin Ltd | Wholesale & retail | 2026 |
| Elvin Automation Services Ltd | Real estate | 2012 |
| Elvin Transport Ltd | Transport & logistics | 2025 |
| Elysium GRP Limited | Manufacturing | 2014 |
| Elysium Hair and Beauty Limited | Other services | 2025 |
| Emaan Consultancy Ltd | Professional & scientific | 2025 |
| Emaan Pharma Ltd | Wholesale & retail | 2021 |
| Emages Innovations Ltd | Professional & scientific | 2024 |
| Embers and Feast Ltd | Real estate | 2024 |
| Embertec Fire & Security Ltd | Administrative & support | 2024 |
| Embody by Ebony Ltd | Arts & recreation | 2026 |
| Embraice Limited | Administrative & support | 2024 |
| Emerald Construction (North West) Ltd | Construction | 2020 |
| Emerald Flooring (Yorkshire) Ltd | Wholesale & retail | 2025 |
| Emerald Parking Ltd | Transport & logistics | 2023 |
| Emerald Support Services Ltd | Health & social care | 2018 |
| EMH Neuro Services Ltd | Health & social care | 2025 |
| Emhart International Holding Ltd | Professional & scientific | 2018 |
| Emhart International Limited | Professional & scientific | 1901 |
| Emily Makings Limited | Other services | 2022 |
| Emily Makings Properties Ltd | Real estate | 2024 |
| Emily Scarf Ltd | Administrative & support | 2021 |
| Emily Superstore Limited | Wholesale & retail | 2026 |
| Eminence Dental Limited | Health & social care | 2022 |
| Emjay Eco Fuels Ltd | Water & waste | 2008 |
| Emjay SAI Ltd | Real estate | 2019 |
| Emma’S Cafe Ltd | Hospitality | 2026 |
| EMP Bouncy Castle Hire Ltd | Administrative & support | 2026 |
| EMP Engineer UK Ltd | Construction | 2024 |
| Emperor Cars Ltd | Wholesale & retail | 2018 |
| Emperor Inns Limited | Hospitality | 2022 |
| Empire Garden Buildings Limited | Manufacturing | 2019 |
| Empire Property Solutions Ltd | Real estate | 2019 |
| Empire Rotherham Ltd | Hospitality | 2023 |
| Empire S60 CIC | Arts & recreation | 2026 |
| Empire Tapes Ltd | Manufacturing | 1993 |
| Empower by Emily Ltd | Health & social care | 2025 |
| Empowering MEN Initiative CIC | Health & social care | 2025 |
| Empowerment Editions Limited | Information & communication | 2024 |
| Empress Building Limited | Hospitality | 2024 |
| EMS Scrap Metal Dealers Ltd | Wholesale & retail | 2015 |
| Emsin Limited | Wholesale & retail | 2025 |
| Emu-J Global Property Ltd | Real estate | 2022 |
| Emuge-Franken UK Limited | Manufacturing | 1988 |
| Emy's Properties Limited | Real estate | 2005 |
| Enatrans Ltd | Transport & logistics | 2025 |
| ENC Industrial Services Ltd | Manufacturing | 2012 |
| Encomdata Ltd | Information & communication | 2025 |
| Encore Musical Theatre Ltd | Arts & recreation | 2021 |
| Endeavour Forklifts Limited | Administrative & support | 2015 |
| Endeavour Industrial Battery Services Ltd | Manufacturing | 2025 |
| Endeavour Inns Ltd | Hospitality | 2022 |
| Endless Styles Limited | Other services | 2012 |
| Endo-X Limited | Health & social care | 2014 |
| Endopro Limited | Health & social care | 2022 |
| Enduheph Limited | Health & social care | 2022 |
| Endurer Ltd | Transport & logistics | 2018 |
| Energy Alloys UK Limited | Mining & quarrying | 2004 |
| Energy Connections Direct Ltd | Professional & scientific | 2018 |
| Energy Observe Limited | Energy | 2009 |
| Energy Repair Specialist Ltd | Construction | 2022 |
| Engineerable Ltd | Manufacturing | 2019 |
| Engineers Warehouse Limited | Extraterritorial | 2006 |
| Enhance Skin Health Ltd | Health & social care | 2018 |
| Eniseeds Ltd | Transport & logistics | 2025 |
| Eniseeds Properties Ltd | Real estate | 2025 |
| Enjami Limited | Wholesale & retail | 2025 |
| Enosome Limited | Wholesale & retail | 2025 |
| Enpac Developments Limited | Real estate | 2021 |
| Enserv Limited | Households | 2025 |
| Ententa Ltd | Education | 2013 |
| Enterprise 2016 Limited | Extraterritorial | 2016 |
| Enterprise Accountancy Services (Rotherham) Limited | Professional & scientific | 2008 |
| Enterprise Couriers Limited | Transport & logistics | 2020 |
| Enterprise Development Solutions Ltd | Professional & scientific | 2015 |
| Enterprise Implementations Ltd | Health & social care | 2020 |
| Entos Limited | Information & communication | 2013 |
| Envirisk Ltd | Professional & scientific | 2020 |
| Enviro Waste Solutions Ltd | Transport & logistics | 2025 |
| Enviroclad Roofing and Cladding Systems Ltd | Construction | 2020 |
| Environ Safety Management Limited | Administrative & support | 2004 |
| Environmental Drainage Solutions Limited | Construction | 2001 |
| Environmental Driveway Solutions Limited | Construction | 2005 |
| Environmental Regeneration Limited | Agriculture & fishing | 2020 |
| Environmental Validation Solutions Limited | Professional & scientific | 2001 |
| Envirotech Industries Limited | Water & waste | 2009 |
| EOS Inc. Ltd | Construction | 2000 |
| EPB Investments Ltd | Real estate | 2004 |
| EPC Express Limited | Construction | 2026 |
| Epialuxe Ltd | Manufacturing | 2025 |
| Epic Customs Automotive Ltd | Wholesale & retail | 2016 |
| Epicentre Trading Ltd | Wholesale & retail | 2014 |
| Epms 20 Ltd | Hospitality | 2025 |
| EPS Electrical & Plumbing Supplies Limited | Construction | 2009 |
| Equal Property Solutions Ltd | Construction | 2022 |
| Equalityre Limited | Water & waste | 2018 |
| Equilibrium Book Keeping and Wages Services Ltd | Professional & scientific | 2016 |