| Deltom Incorporated Limited | Information & communication | 2011 |
| Delu Truck Ltd | Transport & logistics | 2022 |
| Deluxe Laser Slimming & Skin Clinic Ltd | Health & social care | 2024 |
| Demex Northern Ltd | Water & waste | 2026 |
| Demiraj Transport Ltd | Transport & logistics | 2023 |
| Demkel Holdings Ltd | Manufacturing | 2019 |
| Demkel UK Limited | Extraterritorial | 2002 |
| Demolition, Contracting & Environmental Services (DCE) Ltd | Construction | 2012 |
| Denali Transport Limited | Transport & logistics | 2025 |
| Denasa Ltd | Other services | 2022 |
| Dene Close Management Company Limited | Real estate | 2017 |
| Denis Transporter Limited | Transport & logistics | 2019 |
| Deniz Catering Ltd | Hospitality | 2022 |
| Denkleen Limited | Information & communication | 2012 |
| Denmark 2018 Ltd | Real estate | 2018 |
| Denny Mellor Plumbing & Central Heating Ltd | Construction | 2025 |
| Dentech IT Ltd | Wholesale & retail | 2019 |
| Denymar Limited | Transport & logistics | 2023 |
| DEO Developments Ltd | Construction | 2022 |
| DEO Investments Ltd | Real estate | 2020 |
| Dependable Cars Limited | Wholesale & retail | 2017 |
| Derby Hill Developments Ltd | Real estate | 2024 |
| Derbyshire Gymnastics Events Ltd | Arts & recreation | 2026 |
| Derbyshire Performance Academy Ltd | Arts & recreation | 2026 |
| Derose Limited | Construction | 2001 |
| Derwent Oaks Ltd | Financial services | 2025 |
| DES Marples Joinery Ltd | Manufacturing | 2023 |
| Desi Fashion Ltd | Wholesale & retail | 2024 |
| Design & Management Services (2020) Ltd | Professional & scientific | 2019 |
| Design Engine Media LAB Ltd | Professional & scientific | 2016 |
| Design Monkey Limited | Professional & scientific | 2018 |
| Design Technical Services Limited | Professional & scientific | 2013 |
| Design Tooling Limited | Manufacturing | 2008 |
| Designsec Ltd. | Professional & scientific | 2023 |
| Desire Desserts UK Ltd | Hospitality | 2021 |
| Desk Creative Ltd | Information & communication | 2023 |
| Dessert Drip Ltd | Wholesale & retail | 2025 |
| Dessert Munch Ltd | Hospitality | 2026 |
| Deur Property Limited | Real estate | 2022 |
| Developing World Healthcare (Ingo) | Education | 2022 |
| Devious Collective Ltd | Information & communication | 2025 |
| Devonshire Care 1 Limited | Health & social care | 2019 |
| Devonshire Care Limited | Professional & scientific | 2008 |
| Devonshire Hill Limited | Financial services | 2021 |
| Dewan Enterprise Ltd | Real estate | 2025 |
| Dewhirst Accountants Ltd | Professional & scientific | 2024 |
| Dexim Labs Ltd | Information & communication | 2017 |
| Dexter Ivan Limited | Wholesale & retail | 2019 |
| Dexter Race Corp Ltd | Manufacturing | 2023 |
| Dexters Pet Shop Ltd | Wholesale & retail | 2009 |
| Dexx Leisure Limited | Hospitality | 2024 |
| Deyu Delivery Ltd | Transport & logistics | 2021 |
| Dezira Services Ltd | Administrative & support | 2025 |
| DF Administration Limited | Arts & recreation | 2016 |
| DF Control Solutions Limited | Administrative & support | 2014 |
| DF Management Services Ltd | Arts & recreation | 2021 |
| DF Music Ltd | Arts & recreation | 2021 |
| DF Property Rental Ltd | Real estate | 2024 |
| DFR Services Ltd | Transport & logistics | 2018 |
| DGE Civil Engineering Ltd | Construction | 2025 |
| DGS Asset Management Limited | Real estate | 2024 |
| DGS Sports Limited | Arts & recreation | 2022 |
| DH Scaffolding (Yorkshire) Limited | Construction | 2025 |
| Dharma Ltd | Wholesale & retail | 2022 |
| DHM Property Ltd | Financial services | 2017 |
| Dhoddu Tech Ltd | Information & communication | 2026 |
| Dial a CAB Rotherham Ltd | Transport & logistics | 2014 |
| Dialog Consultants Limited | Professional & scientific | 2016 |
| Diamond 1 Car Wash Ltd | Wholesale & retail | 2017 |
| Diamond Cleaning Service Yorkshire Ltd | Administrative & support | 2023 |
| Diamond Dahlia Services Limited | Extraterritorial | 2014 |
| Diamond Dragon Tooling Ltd | Construction | 2025 |
| Diamond Shine Cleaning Services Ltd | Administrative & support | 2016 |
| Diamond Shine Cleans Ltd | Administrative & support | 2025 |
| Diamonds Tanning and Beauty Salon Limited | Other services | 2023 |
| Dice Electrical Contractors Ltd | Construction | 2025 |
| Digit Eyes Ltd | Information & communication | 2022 |
| Digital Dojo Ltd | Financial services | 2022 |
| Digital Sahiwal Ltd | Information & communication | 2026 |
| Digital Steel Consultants Ltd | Professional & scientific | 2018 |
| Digitalsky Limited | Information & communication | 2013 |
| Digitech Business Services Ltd | Administrative & support | 2019 |
| Dignitas Ltd | Health & social care | 2024 |
| Dijiserve UK Ltd | Other services | 2025 |
| Dimensions Construction Ltd | Construction | 2016 |
| Dingozi Transport Ltd | Transport & logistics | 2024 |
| Dinu Trans Ltd | Transport & logistics | 2021 |
| Diorre Vysion Ltd | Health & social care | 2019 |
| Direct (Import & Wholesale) Co Limited | Wholesale & retail | 2011 |
| Direct Construction Limited | Construction | 2010 |
| Direct Gravel Ltd | Wholesale & retail | 2021 |
| Direct Hospitality Management Ltd | Hospitality | 2023 |
| Direct Imports & Wholesale Co LLP | | 2011 |
| Direct Plumbing Solutions Limited | Construction | 2018 |
| Direct U-Tilities Ltd | Construction | 2023 |
| Direct Vehicle Service Centres Ltd | Wholesale & retail | 2013 |
| Directhoses Ltd | Wholesale & retail | 2012 |
| Direkt Doors Limited | Construction | 2014 |
| Dirisala Services Limited | Wholesale & retail | 2016 |
| Discount Bedrooms Ltd | Wholesale & retail | 2013 |