| Crossfit Vita-Ray Ltd | Arts & recreation | 2015 |
| Crown Care Rossendale Limited | Wholesale & retail | 2019 |
| Crown Farm Lodges Limited | Hospitality | 2019 |
| Crownstead Ltd | Professional & scientific | 2025 |
| Crowther City Consultants Ltd | Professional & scientific | 2017 |
| CTS Properties (NW) Ltd | Real estate | 2020 |
| Cubano Club Ltd | Hospitality | 2024 |
| Cube Facades Ltd | Construction | 2010 |
| Cubelow Clough Trading Ltd | Agriculture & fishing | 2025 |
| Cubit International Limited | Professional & scientific | 2016 |
| Cultivate-Em | Professional & scientific | 2006 |
| Culture Rise Ltd | Administrative & support | 2024 |
| Cumbria Court (Prestwich) Management Limited | Households | 1979 |
| Cunniff Joel Limited | Construction | 2019 |
| Curley Thirty Three Limited | Information & communication | 2018 |
| Cursed Tales Ltd | Arts & recreation | 2021 |
| Customer Care Company Ltd. | Information & communication | 1998 |
| Cybertec Limited | Professional & scientific | 2014 |
| D & C Logistics NW Ltd | Transport & logistics | 2025 |
| D & L Donovan Properties Ltd | Real estate | 2019 |
| D & R Cleaning Services (NW) Ltd | Other services | 2007 |
| D a O Construction Ltd | Construction | 2023 |
| D Hall Groundwork Ltd | Construction | 2016 |
| D L Site Solutions Ltd | Construction | 2024 |
| D R Engineering Design Ltd | Professional & scientific | 2016 |
| D&D Residential Property Ltd | Real estate | 2024 |
| D.R.C.M Construction Ltd | Construction | 2025 |
| D.R.Ferguson Enterprises Limited | Construction | 2018 |
| Dads and Kids CIC | Arts & recreation | 2020 |
| Daffodil Blinds Ltd | Construction | 2017 |
| Dairy Food and Juice Consulting Limited | Professional & scientific | 2007 |
| Daisarm Limited | Professional & scientific | 2018 |
| Dalby & Jones Limited | Real estate | 2024 |
| DAN Property Maintenance Ltd | Real estate | 2024 |
| DAN Property Refurb Ltd | Construction | 2025 |
| Dancewear Supplies Limited | Wholesale & retail | 2016 |
| Dan’S MAN and Van Services Ltd | Transport & logistics | 2023 |
| Darling Buds of Rossendale Limited | Wholesale & retail | 2021 |
| Darlington Direct Deliveries Ltd | Transport & logistics | 2025 |
| DAS IT Services Ltd | Information & communication | 2025 |
| David Clegg Transport Servies Ltd | Professional & scientific | 2025 |
| Davies Developments Renovations Ltd | Real estate | 2024 |
| Davies TL Properties Limited | Real estate | 2024 |
| Dawnvale Estates Ltd | Real estate | 2023 |
| Dazzle Group Limited | Information & communication | 2020 |
| DB Travel Limited | Administrative & support | 2023 |
| DC Audio Ltd | Information & communication | 2023 |
| Dean Lane Breakers Limited | Wholesale & retail | 2025 |
| Dean Rose Developments Limited | Construction | 2025 |
| Dekton Doors Ltd | Construction | 2021 |
| Delivery 555 Ltd | Transport & logistics | 2019 |
| Delivery Plus Ltd | Transport & logistics | 2007 |
| Delta Management Holdings Ltd | Professional & scientific | 2024 |
| Deluxe Tanning Ltd | Other services | 2025 |
| Demolition 1 Limited | Wholesale & retail | 2019 |
| Deni-Deni Ltd | Manufacturing | 2024 |
| Denise Bolton Limited | Health & social care | 2018 |
| Dentistry Air & Equipment Ltd | Manufacturing | 2026 |
| Denu Bathrooms Ltd | Wholesale & retail | 2023 |
| Deserts Miss the Rain Ltd | Professional & scientific | 2022 |
| Design North West Limited | Professional & scientific | 2026 |
| Design Retro Works Limited | Wholesale & retail | 2012 |
| Dessert Foods Ltd | Hospitality | 2022 |
| Dexter Paints Holdings Limited | Real estate | 1995 |
| DFC Technologies Limited | Extraterritorial | 2011 |
| Diddy Dribblers Ltd | Extraterritorial | 2016 |
| Diplomat Travel Ltd | Transport & logistics | 2019 |
| Direct Products (UK) Limited | Wholesale & retail | 2002 |
| Discovery Lettings Limited | Real estate | 2024 |
| Divide & Profit Investments Ltd | Real estate | 2024 |
| Divide & Profit Investments Trustee Ltd | Real estate | 2024 |
| DJ Developments(Lancs) Ltd | Real estate | 2024 |
| DJC Enterprises Limited | Professional & scientific | 2008 |
| DK Brightway Investments Ltd | Real estate | 2020 |
| DK Empire Limited | Real estate | 2025 |
| DKH Civils Ltd | Construction | 2026 |
| DL Plumbing & Heating Systems Ltd | Construction | 2018 |
| DL Services (NW) Ltd | Transport & logistics | 2022 |
| DLA Building and Civil Engineers Ltd | Construction | 2020 |
| DM Electrical Ross UK Ltd | Construction | 2017 |
| DM Properties Ross UK Ltd | Real estate | 2024 |
| DMC Inspection Limited | Professional & scientific | 2023 |
| DNE Logistics Limited | Transport & logistics | 2018 |
| Doctor Sparkles Limited | Health & social care | 2010 |
| Domestic Goddess Rossendale Limited | Households | 2011 |
| Donnelly Interiors Ltd | Wholesale & retail | 2022 |
| Don`T Panic Projects Limited | Professional & scientific | 2005 |
| Downham Holdings (North West) Limited | Financial services | 2009 |
| Drag and Drink Ltd | Hospitality | 2025 |
| Dream AI Ltd | Information & communication | 2018 |
| Drink Dance Drink Ltd | Hospitality | 2025 |
| DRL Trading Ltd | Wholesale & retail | 2002 |
| Drunk Swan Ltd | Hospitality | 2024 |
| DSO Investments Ltd | Real estate | 2021 |
| DTB Fabrication Ltd | Manufacturing | 2023 |
| Dunlaverock Limited | Information & communication | 2008 |
| Dynamic Coatings Ltd | Construction | 2023 |
| E.Novation UK Limited | Information & communication | 2001 |
| E.Taylor,Sons,& Company,Limited | Wholesale & retail | 1899 |
| EA Blinds Limited | Wholesale & retail | 2018 |