| DE Divine Service Limited | Administrative & support | 2015 |
| DE Douglas Property Services Ltd | Real estate | 2021 |
| DE Quilox Lounge Ltd | Hospitality | 2019 |
| De-Risking Solutions Ltd | Professional & scientific | 2015 |
| Dean & Co. Limited | Professional & scientific | 2024 |
| Dean Goodwin Ltd | Real estate | 2024 |
| Dean's Used Cars Limited | Extraterritorial | 2005 |
| Deans Estate Management Company Limited | Real estate | 1990 |
| Debby Marshall Limited | Health & social care | 2020 |
| Debestdor Care Limited | Administrative & support | 2019 |
| Debstar PA Limited | Real estate | 2022 |
| Decabin Ltd | Wholesale & retail | 2022 |
| Decca Group Ltd | Education | 2016 |
| Deck Ltd | Wholesale & retail | 2017 |
| Deckt Limited | Professional & scientific | 2021 |
| Decoecco Limited | Construction | 2024 |
| Decor Vision Limited | Information & communication | 2025 |
| Decota Gifts Ltd | Wholesale & retail | 2025 |
| Decripdz Ltd | Wholesale & retail | 2024 |
| Deda Carpentry Limited | Construction | 2014 |
| DEE PT Studio Limited | Health & social care | 2026 |
| Dee's Drinks Ltd | Hospitality | 2018 |
| DEE777 Maintenance Limited | Households | 2020 |
| Deemorllah Ltd | Construction | 2020 |
| Deeoged Ltd | Wholesale & retail | 2022 |
| Deep and JIT Limited | Professional & scientific | 2018 |
| Deepak Kumar Ltd | Construction | 2018 |
| Deepak Legal Limited | Professional & scientific | 2026 |
| Deepsea 23 Resources Ltd | Public administration | 2018 |
| Deevyne Mortgage Services Limited | Financial services | 2024 |
| Defendtech Solutions IT Services Ltd | Information & communication | 2023 |
| Deivyd Limited | Construction | 2025 |
| Deixis Engineering Ltd | Professional & scientific | 2021 |
| Delamey Limited | Administrative & support | 2014 |
| Delaney FOX Construction Ltd | Construction | 2015 |
| Delaney FOX Properties Limited | Real estate | 2025 |
| Delaney's Limited | Construction | 2013 |
| Delaware Communications Limited | Extraterritorial | 1985 |
| Delce Hand Car Wash Ltd | Wholesale & retail | 2015 |
| Delectanibble Limited | Hospitality | 2015 |
| Delhi Darbaar Limited | Hospitality | 2017 |
| Delight Beds & Furniture Ltd | Wholesale & retail | 2010 |
| Delios Maximus Limited | Professional & scientific | 2023 |
| Dellmoor Ltd | Wholesale & retail | 2018 |
| Dellta Construction Ltd | Construction | 2025 |
| Delphina PVT Ltd | Real estate | 2022 |
| Delta Construct Ltd | Construction | 2022 |
| Delta Contractors Ltd | Construction | 2018 |
| Delta Membrane Holdings Limited | Financial services | 2017 |
| Delta Membrane Systems Limited | Wholesale & retail | 1998 |
| Delta Tenant Managed Organisation Limited | Real estate | 2005 |
| Deltone Security Services Limited | Administrative & support | 2006 |
| Deluxe Hair Extensions Academy Ltd | Other services | 2019 |
| Deluxe Nails & Spa Romford Limited | Other services | 2022 |
| Deluxe Studios Ltd | Construction | 2026 |
| Demira & Co. Ventures Limited | Administrative & support | 2019 |
| Demo MEN (London) UK Ltd | Administrative & support | 2020 |
| Demo Properties Limited | Real estate | 2010 |
| Demolete Ltd | Construction | 2013 |
| Demon Angel Ltd | Transport & logistics | 2017 |
| Demzat Consulting UK Ltd | Transport & logistics | 2014 |
| DEN of Tech Limited | Wholesale & retail | 2019 |
| DEN of Technology Ltd | Wholesale & retail | 2022 |
| Dencor Limited | Construction | 2025 |
| Denergii Ltd | Professional & scientific | 2024 |
| Deniz Home Art Ltd | Wholesale & retail | 2025 |
| Denjay Logisticks UK Ltd | Transport & logistics | 2026 |
| Denning Real Estate Ltd | Real estate | 2021 |
| Densure Limited | Health & social care | 2021 |
| Dent Busters UK Limited | Wholesale & retail | 2005 |
| Dentality Limited | Health & social care | 2010 |
| Dentoreema Ltd | Health & social care | 2023 |
| Denver Electrical Limited | Construction | 2016 |
| Denys Maruntelu Ltd | Transport & logistics | 2020 |
| DEO Events Ltd | Arts & recreation | 2024 |
| Deol Shopfitters Ltd | Construction | 2016 |
| Deon Construction Ltd | Construction | 2023 |
| Deploy Services Limited | Construction | 2019 |
| Depo Group Ltd | Construction | 2024 |
| Derek Leftly & Co. Ltd. | Water & waste | 1996 |
| Derek Mcdonald Holdings Limited | Real estate | 2018 |
| Deria Consulting Limited | Information & communication | 2007 |
| Derin Construction Ltd | Construction | 2025 |
| Derivative Solutions Ltd | Professional & scientific | 2014 |
| Derivatives Connect Private Limited | Information & communication | 2011 |
| Derivsource Limited | Administrative & support | 2010 |
| Dermacare Aesthetic Clinic Limited | Other services | 2025 |
| Deronmu Foods Limited | Wholesale & retail | 2020 |
| Derplan Ltd | Hospitality | 2023 |
| Derrick Logistics Limited | Transport & logistics | 2016 |
| Desaur LLP | | 2007 |
| Descendo Limited | Manufacturing | 2018 |
| Deseoo Co.Uk Ltd | Administrative & support | 2015 |
| Desh Masala Ltd | Wholesale & retail | 2024 |
| Design and Design Limited | Professional & scientific | 2006 |
| Design Haus Group Limited | Construction | 2020 |
| Design Haus Site Services Ltd | Construction | 2021 |
| Design My Date Ltd | Extraterritorial | 2021 |
| Design Tank London Limited | Professional & scientific | 2015 |
| Designer HUT Ltd | Wholesale & retail | 2024 |