| Smith-Alexander Foundation CIC | Education | 2024 |
| Smith-Alexander Ltd | Information & communication | 2025 |
| Smithfield Beef Company Ltd | Wholesale & retail | 2018 |
| Smji Property Development Ltd | Construction | 2026 |
| Smkr Medics Ltd | Health & social care | 2015 |
| Smmaa Property Ltd | Real estate | 2021 |
| Smokescreen LDN Limited | Hospitality | 2022 |
| Smooth Cars Hire Ltd | Administrative & support | 2025 |
| Smooth Executive Transfer Ltd | Administrative & support | 2025 |
| Smooth Media Ltd | Information & communication | 2022 |
| Smooth Move Inventory Ltd | Administrative & support | 2018 |
| Smooth Transfer Ltd | Transport & logistics | 2023 |
| SMQ Homes Ltd | Real estate | 2018 |
| SMR Accountants Limited | Professional & scientific | 2014 |
| SMS & Partners Ltd | Professional & scientific | 2016 |
| SMS Fabricators Ltd | Manufacturing | 2021 |
| SMS Properties (London) Ltd | Real estate | 2018 |
| Smudger Taverns Limited | Hospitality | 2008 |
| SN Dryliner Ltd | Construction | 2024 |
| SN Meds Ltd | Health & social care | 2026 |
| Snackcart Ltd | Wholesale & retail | 2024 |
| Snak London Ltd | Hospitality | 2016 |
| Snakes Lane Management Limited | Real estate | 2015 |
| Snap Dealz Ltd | Wholesale & retail | 2025 |
| Snap Fresh Solutions Ltd | Wholesale & retail | 2017 |
| Snap Spares Ltd | Wholesale & retail | 2024 |
| Snapmart Ltd | Wholesale & retail | 2024 |
| Snapper Holdings Limited | Financial services | 2021 |
| Snapper Trading and Consultancy Limited | Professional & scientific | 2022 |
| SNC Associates Limited | Health & social care | 2014 |
| SNC Facilities Management Ltd | Construction | 2004 |
| SNC Scaffolding Ltd | Construction | 2012 |
| Sneaje Properties Ltd | Real estate | 2021 |
| Snip & Shape Beauty Limited | Other services | 2014 |
| SNL Consultants Ltd | Financial services | 2010 |
| SNM Properties Ltd | Real estate | 2025 |
| Snopes Solutions Ltd | Construction | 2017 |
| Snow & Family Enterprise Ltd | Construction | 2019 |
| Snow FOX Properties Ltd | Real estate | 2023 |
| Snow Sister Homes Ltd | Real estate | 2026 |
| Snowing Data Limited | Information & communication | 2004 |
| SNS Motor Getawayz Ltd | Wholesale & retail | 2023 |
| SNS Tools Ltd | Wholesale & retail | 2025 |
| SNT Services Ltd | Other services | 2020 |
| SO Group Holdings Limited | Real estate | 2017 |
| SO Property & Management Ltd | Construction | 2023 |
| So&I Ltd | Construction | 2019 |
| Soaring Above Ltd | Education | 2024 |
| Sober Events UK Limited | Information & communication | 2017 |
| Soccerdays RM Ltd | Education | 2026 |
| Social and Environmental Justice | Education | 2023 |
| Social Labs Digital Ltd | Professional & scientific | 2024 |
| Sodhi Builders Limited | Administrative & support | 2014 |
| Soelegence Trading Limited | Wholesale & retail | 2024 |
| Soft Machine Films Ltd | Arts & recreation | 2020 |
| Softace Ltd | Information & communication | 2019 |
| Softbenz Infosys Ltd | Information & communication | 2026 |
| Softbond Limited | Real estate | 1997 |
| Softech Cloud Limited | Wholesale & retail | 2022 |
| Softech Media Ltd | Information & communication | 2014 |
| Softlabs Limited | Information & communication | 2014 |
| Software a S Holdings Limited | Financial services | 2026 |
| Software a S Limited | Information & communication | 1983 |
| Software Design Smart Ltd | Information & communication | 2022 |
| Software Test Solutions Limited | Information & communication | 2018 |
| Softworld Limited | Information & communication | 2015 |
| Soil Properties Ltd | Real estate | 2024 |
| Soko's Mobile Mechanic Ltd | Wholesale & retail | 2022 |
| Sokoli Ltd | Real estate | 2021 |
| Sokoli Transporting Ltd | Transport & logistics | 2020 |
| SOL Wear Ltd | Wholesale & retail | 2025 |
| Sola Tech Ltd | Construction | 2025 |
| Solace Estates Limited | Real estate | 2020 |
| Solace Point Property Limited | Real estate | 2025 |
| Solad Ventures Limited | Health & social care | 2012 |
| Solano Assist Ltd | Administrative & support | 2018 |
| Solav KRD Ltd | Wholesale & retail | 2025 |
| Sold OUT Digital Ltd | Information & communication | 2026 |
| Sold Together Ltd | Wholesale & retail | 2026 |
| Soldanscompany Ltd | Arts & recreation | 2025 |
| Sole Stepping Ltd | Wholesale & retail | 2020 |
| Solid Brick Solutions Ltd | Construction | 2018 |
| Solid Ventures Limited | Real estate | 2005 |
| Solidus FM Ltd | Other services | 2026 |
| Solmer Ltd | Wholesale & retail | 2010 |
| Solmion Ltd | Information & communication | 2026 |
| Solo-Bros Ltd | Real estate | 2025 |
| Solofish Properties Ltd | Real estate | 2018 |
| Solstice Gaming Limited | Wholesale & retail | 2025 |
| Solum Construction Ltd | Construction | 2024 |
| Solus Informatics Ltd | Information & communication | 2010 |
| Solution Electrical Ltd | Construction | 2021 |
| Solution Plus Inc Ltd | Manufacturing | 2020 |
| Solux Services Ltd | Professional & scientific | 2009 |
| Solvara Limited | Wholesale & retail | 2025 |
| Solve IT Tuition Ltd | Education | 2022 |
| Solzen Ltd | Wholesale & retail | 2022 |
| Somage Solutions Services Ltd | Administrative & support | 2020 |
| Somax Properties Ltd | Real estate | 2018 |
| Sommilito Sahitya O Sangskritik Parishad Juktorajya Ltd | Administrative & support | 2019 |