| S&Syou Limited | Real estate | 2024 |
| S&T Assets Ltd | Real estate | 2019 |
| S&W Hair Salon Ltd | Other services | 2025 |
| S'Algar Villas Limited | Real estate | 2007 |
| S'Dohk Limited | Hospitality | 2022 |
| S. a. ALL Construction Ltd | Construction | 2015 |
| S. Thorogood Contracting Limited | Agriculture & fishing | 2022 |
| S.A.V.O. Holdings Ltd | Financial services | 2025 |
| S.B Motor Group Limited | Wholesale & retail | 2022 |
| S.D. LEE Plumbing & Heating Ltd | Construction | 2015 |
| S.G. Lipscomb Ltd | Administrative & support | 1997 |
| S.I.A. Consultancy Ltd | Professional & scientific | 2021 |
| S.J.M.J. Ltd | Administrative & support | 2014 |
| S.J.R. Associates Limited | Administrative & support | 1997 |
| S.K Catering Services Limited | Hospitality | 2017 |
| S.O.C.A Engineering Ltd | Construction | 2021 |
| S.O.S Build Ltd | Construction | 2024 |
| S.S. Dhot Property Ltd | Real estate | 2024 |
| S.S.V Builders Limited | Construction | 2025 |
| S.S.V. OFF Licence Limited | Wholesale & retail | 2020 |
| S.T Waste Management Ltd | Water & waste | 2026 |
| S.V.Autoval Limited | Wholesale & retail | 2016 |
| S.V.E Rail Ltd | Construction | 2025 |
| S3 Care Solutions Limited | Administrative & support | 2024 |
| S4 International Ltd | Administrative & support | 2015 |
| S4S Ventures Limited | Real estate | 2022 |
| SA Bliss Ltd | Wholesale & retail | 2023 |
| SA Builders & Contractors Ltd | Construction | 2003 |
| SA Globe Ltd | Wholesale & retail | 2021 |
| SA Investment Solutions Limited | Real estate | 2021 |
| SA Investment Three Limited | Real estate | 2024 |
| SA Investment Two Limited | Real estate | 2024 |
| SA Kebab Ltd | Hospitality | 2026 |
| SA Productions Ltd | Arts & recreation | 2023 |
| SA370 Limited | Hospitality | 2019 |
| Saaas ACP Ltd | Health & social care | 2023 |
| Saadi Enterprises Ltd | Wholesale & retail | 2023 |
| Saaf Associates Ltd | Professional & scientific | 2022 |
| Saam Foods Ltd | Hospitality | 2023 |
| Saancom Ltd | Construction | 2019 |
| Saanvi Healthcare Ltd | Health & social care | 2014 |
| Saashi London Ltd | Extraterritorial | 2018 |
| Saasvaap UK Ltd | Information & communication | 2022 |
| SAB Home Improvement Ltd | Construction | 2017 |
| SAB Media Limited | Wholesale & retail | 2018 |
| SAB Tech Consult Ltd | Construction | 2020 |
| Saba & Naba Consultancy Limited | Administrative & support | 2022 |
| Saba Arham Ltd | Wholesale & retail | 2025 |
| Saba Enterprises Ltd Ltd | Health & social care | 2021 |
| Sabah IQ Ltd | Wholesale & retail | 2025 |
| Sabaifly Ltd | Administrative & support | 2025 |
| Sabaoth Investments Limited | Real estate | 2024 |
| Sabev Ltd | Construction | 2020 |
| Sabina's Deep Clean Ltd | Administrative & support | 2026 |
| Sabor & Aroma Ltd | Wholesale & retail | 2026 |
| Sabtech Limited | Information & communication | 2016 |
| Sachin Mpharm Ltd | Professional & scientific | 2020 |
| Sada Infotech Ltd | Information & communication | 2023 |
| Sadat Brothers Limited | Wholesale & retail | 2025 |
| Sadiaartistry Ltd | Other services | 2016 |
| Sadiamubeen Limited | Real estate | 2025 |
| Sadipe & Co Ltd | Real estate | 2023 |
| Sadipe Residential Ltd | Real estate | 2025 |
| Safa-Rail Limited | Construction | 2016 |
| Safaeaesthetic Ltd | Other services | 2025 |
| Safe and Secured Ltd | Administrative & support | 2021 |
| Safe Bridge Care Services Limited | Health & social care | 2025 |
| Safe Choice Fast Food Ltd | Hospitality | 2017 |
| Safe Corp Limited | Wholesale & retail | 2022 |
| Safe KID Chadwell Limited | Health & social care | 2025 |
| Safe Lifting Techniques Limited | Construction | 2023 |
| Safe Operations Ltd | Construction | 2021 |
| Safe Places Today Ltd | Professional & scientific | 2020 |
| Safe Secure Electrics Limited | Professional & scientific | 2021 |
| Safe Steps First AID Ltd | Education | 2026 |
| Safensecure Locks Ltd | Administrative & support | 2016 |
| Safeplot Limited | Financial services | 2022 |
| Safetow (Vehicle Security) Limited | Wholesale & retail | 1975 |
| Safety First Global Limited | Professional & scientific | 2024 |
| Safety First Security 2010 Ltd | Administrative & support | 2010 |
| Safety Hire Ltd | Transport & logistics | 2016 |
| Safetyfirst Consult Limited | Professional & scientific | 2025 |
| Saffron Glamour UK Ltd | Wholesale & retail | 2021 |
| Saffron Spice Romford Ltd | Hospitality | 2026 |
| Safield Distributions Ltd | Wholesale & retail | 2006 |
| Safield Holdings Limited | Financial services | 2022 |
| Safura International Limited | Wholesale & retail | 2001 |
| Saga Consultancy Services Ltd | Real estate | 2024 |
| Saga Investment and Property Ltd | Real estate | 2023 |
| Saga Technology Limited | Information & communication | 2007 |
| Sage & ASH Ltd | Hospitality | 2026 |
| Sage Sanctuary Limited | Wholesale & retail | 2023 |
| Sagewood Collective Limited | Wholesale & retail | 2026 |
| Sagr Properties UK Ltd | Real estate | 2019 |
| Sagro Property Management Ltd | Households | 2024 |
| Sagtech Services Ltd | Administrative & support | 2019 |
| Sagwal Construction Ltd | Construction | 2018 |
| Sahaab Intl Limited | Professional & scientific | 2016 |
| Sahan Aria LLP | | 2024 |
| Sahana Foods Limited | Wholesale & retail | 2009 |