| Em-Secure Ltd | Information & communication | 2007 |
| Em-Secure Trading Ltd | Administrative & support | 2020 |
| Emathy Fast Food Ltd | Hospitality | 2024 |
| Embargo Streetwear Limited | Wholesale & retail | 2023 |
| Emdirely Ltd | Health & social care | 2021 |
| Emea Critical Power Solutions Ltd | Construction | 2022 |
| Emerald Bridges Children Psychological and Assessment Services Ltd | Education | 2024 |
| Emerald Forge Developments Limited | Administrative & support | 2016 |
| Emerald Fresh Ltd | Professional & scientific | 2023 |
| Emerge Academy Ltd | Education | 2026 |
| Emerge Aesthetics Ltd | Other services | 2018 |
| Emgada Services Limited | Health & social care | 2019 |
| Emily Norris Tuition Limited | Education | 2014 |
| Emin & Sons Limited | Wholesale & retail | 2011 |
| Emma Court RTM Company Limited | Households | 2025 |
| Emma Matthews Coaching and Communications Limited | Professional & scientific | 2018 |
| Emmanuel Services Ltd | Real estate | 2021 |
| Emmaus Developments Limited | Real estate | 2003 |
| Emmbrook Limited | Construction | 2007 |
| Empire Drywall Solutions Limited | Construction | 2008 |
| Empire Fabrications Ltd | Manufacturing | 2019 |
| Empire House (Rochester) Limited | Real estate | 2018 |
| Empire Outdoor Ltd | Administrative & support | 2017 |
| Empire Property Group Kent Limited | Construction | 2026 |
| Empire Travel (Kent) Limited | Transport & logistics | 2023 |
| Empiria Events Limited | Administrative & support | 2023 |
| Enbuilding Service Limited | Construction | 2017 |
| Enchanting Events Limited | Wholesale & retail | 2022 |
| Encon Technic UK Limited | Extraterritorial | 2007 |
| Encrypted Audio Ltd | Information & communication | 2015 |
| END of Cleaning Ltd | Administrative & support | 2023 |
| Endeavour Chauffeur Drive Ltd | Extraterritorial | 2022 |
| Endurance Care Services Limited | Public administration | 2022 |
| Enea Grup Limited | Construction | 2024 |
| Energy Events DNB Ltd | Arts & recreation | 2023 |
| Energy Price Compare Limited | Energy | 2016 |
| Energy Storage and Management Solutions Ltd | Professional & scientific | 2019 |
| Engage Business Development Ltd | Administrative & support | 2024 |
| Engineered Security Solutions Limited | Administrative & support | 2018 |
| Engineering Aurora Ltd | Administrative & support | 2025 |
| Engineering Solution Services Limited | Energy | 2015 |
| Enterprise Plumbing Ltd | Construction | 2014 |
| Entity Connect Ltd | Construction | 2017 |
| Entwined Changes Limited | Other services | 2018 |
| Envirocure Limited | Administrative & support | 2002 |
| Enzoda Specialist Cars Limited | Wholesale & retail | 2021 |
| Epharmos Ltd | Health & social care | 2014 |
| Ephatha Ltd | Information & communication | 2013 |
| Epic Landscaping Ltd | Administrative & support | 2023 |
| Epic Valeting & Detailing Ltd | Administrative & support | 2025 |
| Epicure Wines Ltd | Wholesale & retail | 2004 |
| Equation Music Sound Recording and Music Publishing Activities Ltd | Information & communication | 2026 |
| Equi-Transport Limited | Agriculture & fishing | 2025 |
| Equimeridian Limited | Professional & scientific | 2022 |
| Equipets Cleaning Services Limited | Other services | 2011 |
| Erando Hand Car Wash Ltd | Administrative & support | 2022 |
| Eric Alexandra Ltd | Construction | 2025 |
| ERJ Developers Limited | Construction | 2011 |
| Erry Transport Limited | Transport & logistics | 2016 |
| ERT Leasing Ltd | Real estate | 2023 |
| ERU Electrics Ltd | Construction | 2017 |
| ES Corporate Entertainment Ltd | Administrative & support | 2015 |
| ES Corporate Marketing Limited | Other services | 2017 |
| ES Lawton Properties Limited | Real estate | 2019 |
| ESC London Services Ltd | Administrative & support | 2019 |
| Escalated Ltd | Construction | 2024 |
| Escu Chauffeurs Limited | Wholesale & retail | 2022 |
| Esivie Care Services Ltd | Health & social care | 2020 |
| ESM Online Services Ltd | Other services | 2022 |
| Esola AI Ltd | Professional & scientific | 2026 |
| Espihomes Limited | Real estate | 2025 |
| Esplanade Estates Ltd | Real estate | 2022 |
| Esplanade Healthcare Limited | Health & social care | 2003 |
| ESS Property Ltd | Hospitality | 2021 |
| Essense of Swag 101 Limited | Wholesale & retail | 2016 |
| EST Consultancy Ltd | Construction | 2015 |
| Esther&Emerald Ltd | Other services | 2017 |
| Estimating and Surveying Services Ltd | Professional & scientific | 2024 |
| Etereo Limited | Health & social care | 2025 |
| Ethical Interiors Limited | Wholesale & retail | 2021 |
| ETK Entertainments Limited | Hospitality | 2025 |
| Etoile Consulting Ltd | Administrative & support | 2025 |
| Etse Services Ltd | Education | 2014 |
| Etta Group Ltd | Real estate | 2026 |
| Eulogia Properties & Construction LLP | | 2024 |
| Euro Afro Shop Limited | Information & communication | 2025 |
| Eurobulk Ltd. | Transport & logistics | 1995 |
| Euroguard Pest Control Limited | Other services | 1994 |
| Euroline Resources Limited | Real estate | 2005 |
| Europens Ltd | Wholesale & retail | 2010 |
| Euroside Construction & Rail Limited | Extraterritorial | 2009 |
| Euroside Construction Limited | Construction | 2007 |
| Euroside Developments Limited | Construction | 2007 |
| Euroside Diamond Drilling Limited | Construction | 2008 |
| Euroside Ground Works Limited | Extraterritorial | 2007 |
| Euroside Group Limited | Administrative & support | 2004 |
| Euroside Labour Supply Limited | Extraterritorial | 2007 |
| Euroside Limited | Extraterritorial | 2007 |
| Euroside Maintenance Limited | Extraterritorial | 2007 |
| Euroside Plant Hire Limited | Administrative & support | 2005 |