| Elnora Picks Ltd | Wholesale & retail | 2025 |
| Elron Fire and Security Ltd | Administrative & support | 2025 |
| Elvorapentatrading Ltd | Wholesale & retail | 2026 |
| Elysiumbybia Limited | Other services | 2026 |
| EMA Trader Ltd | Wholesale & retail | 2026 |
| Emaan Construction Ltd | Construction | 2020 |
| Embassy Records Ltd | Wholesale & retail | 2024 |
| Emerging Solution Ltd | Information & communication | 2015 |
| Eminence Windows and Doors Ltd | Construction | 2026 |
| Emma Lord Consultancy Limited | Information & communication | 2016 |
| Emma's Crazy Creatures Limited | Arts & recreation | 2024 |
| Empire Bamford Ltd | Transport & logistics | 2019 |
| Empire Car Hire (UK) Ltd | Extraterritorial | 2014 |
| Empire Castleton Ltd | Transport & logistics | 2019 |
| Empire Dental Ltd | Health & social care | 2025 |
| Empire Estate Group Ltd | Real estate | 2025 |
| Empire Events Rochdale Limited | Hospitality | 2016 |
| Empire Executive Travel Ltd | Other services | 2019 |
| Empire Glazing Solutions Ltd | Construction | 2015 |
| Empire Group (UK) Limited | Administrative & support | 2011 |
| Empire Luxury Limited | Transport & logistics | 2013 |
| Empire NW One Ltd | Administrative & support | 2020 |
| Empire Properties Group Ltd | Real estate | 2025 |
| Empire Travel Group Limited | Transport & logistics | 2018 |
| Empire X Ltd | Wholesale & retail | 2023 |
| Empires Goods Ltd | Wholesale & retail | 2026 |
| Employabl CIC | Education | 2025 |
| Emporium 360 Ltd | Wholesale & retail | 2024 |
| Emsquaredpartylab Ltd | Hospitality | 2026 |
| Emvino Solutions Ltd | Wholesale & retail | 2021 |
| Enable Cooling and Heating Limited | Construction | 2026 |
| Encore Group Midlands Limited | Construction | 2025 |
| Encouragingyou Community Interest Company | Education | 2022 |
| Endevr Digital Ltd | Information & communication | 2026 |
| ENDOLIFE4UK Ltd | Health & social care | 2018 |
| Energy Driver Limited | Construction | 2024 |
| Energy First Solutions Ltd | Financial services | 2026 |
| Energy Funding Service | Administrative & support | 2021 |
| Energy Future Solutions Ltd | Construction | 2026 |
| Engineered Components Limited | Professional & scientific | 2013 |
| Enhance Designs Limited | Professional & scientific | 2008 |
| Enhance International Limited | Administrative & support | 2006 |
| Enhanced Manchester Ltd | Other services | 2021 |
| ENI Events & Catering Ltd | Hospitality | 2026 |
| Enigmatix Global Ltd | Information & communication | 2024 |
| Enijie Ltd | Professional & scientific | 2024 |
| Enlive Mart Ltd | Wholesale & retail | 2025 |
| Enoch Consult Ltd | Administrative & support | 2018 |
| Enrich Recruitment Ltd | Administrative & support | 2014 |
| Ensure Consulting Limited | Professional & scientific | 2021 |
| Entaracutters Limited | Wholesale & retail | 2022 |
| Enterprise UK Property Group Limited | Construction | 2019 |
| Entreedom Apparels Ltd | Wholesale & retail | 2025 |
| Enviro (Broadbent Moss) Limited | Water & waste | 2023 |
| Enviro (Elland North) Limited | Water & waste | 2023 |
| Enviro (Latchford) Limited | Extraterritorial | 1985 |
| Enviro (Meek Street) Limited | Water & waste | 2023 |
| Enviro (Regent Street) Limited | Water & waste | 2023 |
| Enviro (Town Farm) Limited | Water & waste | 2023 |
| Enviro Site Holdings Limited | Financial services | 2021 |
| Enviro Tyres Recycling Limited | Wholesale & retail | 2021 |
| Enviroflame Combustion Services Ltd | Construction | 2023 |
| Environmental Safety Solutions Limited | Wholesale & retail | 2023 |
| Envision Business Services Ltd | Professional & scientific | 2025 |
| Envision Wedding Cars Ltd | Transport & logistics | 2020 |
| EON Accountants Ltd | Professional & scientific | 2026 |
| Eonix Ltd | Wholesale & retail | 2026 |
| Epah Training Ltd | Arts & recreation | 2021 |
| Epic Windows Ltd | Manufacturing | 2024 |
| Epidermlux Limited | Wholesale & retail | 2024 |
| Epitekhuk Ltd | Wholesale & retail | 2024 |
| Epoch Innovations Limited | Information & communication | 2025 |
| Epsol Limited | Professional & scientific | 2023 |
| Equire Solutions Ltd | Information & communication | 2017 |
| Equity Car Hire Ltd | Other services | 2014 |
| ER Direct Ltd | Wholesale & retail | 2019 |
| ER Education Consultants Ltd | Education | 2020 |
| ER Traders Ltd | Wholesale & retail | 2016 |
| ERB (Somerset) Ltd | Administrative & support | 2018 |
| Erbe Ltd | Wholesale & retail | 2019 |
| Ernh Consulting Limited | Professional & scientific | 2023 |
| Errwh E-Commerce Ltd | Wholesale & retail | 2026 |
| ERS Energy Ltd | Construction | 2023 |
| ERT Consultants Limited | Professional & scientific | 2004 |
| ES Business Consulting Services Ltd | Professional & scientific | 2025 |
| ES Optical Group Ltd | Wholesale & retail | 2025 |
| ESA Consultancy Limited | Real estate | 2022 |
| Esbp Scaffolding Ltd | Construction | 2024 |
| Escape & Elegance Ltd | Manufacturing | 2025 |
| Escape 9-5 Digitals Limited | Wholesale & retail | 2025 |
| Eshaan Enterprises Ltd | Wholesale & retail | 2014 |
| ESJ Editing Ltd | Information & communication | 2022 |
| Espak Ltd | Transport & logistics | 2023 |
| Espresso Underground Limited | Wholesale & retail | 2023 |
| Essay Trading Ltd | Wholesale & retail | 2023 |
| Essentials X Ltd | Wholesale & retail | 2022 |
| Essentiobrands Ltd | Wholesale & retail | 2025 |
| Esspee Naturals Ltd | Wholesale & retail | 2017 |
| Essro Limited | Wholesale & retail | 2019 |
| Estelle Properties Limited | Real estate | 2025 |