| Dreamz Decors Ltd. | Wholesale & retail | 2022 |
| Dredge Electrical Ltd | Energy | 2026 |
| Dress Codex Limited | Wholesale & retail | 2022 |
| Drippin Ltd | Wholesale & retail | 2025 |
| Drivemates Private Limited | Transport & logistics | 2024 |
| Driven by Data Productions Limited | Professional & scientific | 2025 |
| Driver Defence Advisory Ltd | Information & communication | 2025 |
| Driveseb Ltd | Transport & logistics | 2019 |
| Drogies Limited | Wholesale & retail | 2003 |
| Drome Limited | Wholesale & retail | 1995 |
| Drone Air Ltd | Professional & scientific | 2024 |
| Drugmart Limited | Health & social care | 2007 |
| Drury Adams Holdings Limited | Professional & scientific | 2008 |
| Drwngsymbls. Ltd | Wholesale & retail | 2025 |
| DRY Core Solutions Limited | Construction | 2025 |
| Drytrek Ltd | Wholesale & retail | 2023 |
| DS & L Property Limited | Real estate | 2022 |
| DSB Construct Limited | Construction | 2017 |
| DSP Risk Management Ltd | Other services | 2021 |
| DTM Consultants Ltd | Professional & scientific | 2025 |
| DTS Checks Ltd | Wholesale & retail | 2026 |
| Dualcraft Limited | Wholesale & retail | 2024 |
| Ductwork Ventilation Services Limited | Construction | 2022 |
| Duece Paddel Center Limited | Arts & recreation | 2025 |
| Duke Street Autopoint Limited | Wholesale & retail | 1999 |
| Dukes MOT Test Centre Limited | Wholesale & retail | 2025 |
| Duncan Hannant Associates Limited | Health & social care | 2014 |
| Dunleavy Estates Ltd | Real estate | 2025 |
| Dunphy Energy Solutions Limited | Manufacturing | 2016 |
| Durbar Tours Ltd | Hospitality | 2019 |
| Dustolex Limited | Manufacturing | 1971 |
| Dutch Doner Kabab Original Limited | Hospitality | 2019 |
| Duuaa Limited | Wholesale & retail | 2025 |
| Duuaa Property Limited | Real estate | 2026 |
| DV Fireblock Limited | Construction | 2020 |
| DW Print Solutions Ltd | Manufacturing | 2023 |
| DW Rochdale Ltd | Wholesale & retail | 2023 |
| DW Sports & Leisure Ltd | Wholesale & retail | 2011 |
| DY Safety Ltd | Health & social care | 2026 |
| Dynamic Canopy Clean Ltd | Administrative & support | 2022 |
| Dynamic PT Systems Limited | Arts & recreation | 2023 |
| Dynatechanalytics Ltd | Information & communication | 2024 |
| Dyson's Drainage & Plumbing Services Ltd | Construction | 2023 |
| Dzotica Limited | Hospitality | 2025 |
| D’Trip Limited | Administrative & support | 2024 |
| E & J Lees Farm Ltd | Administrative & support | 2013 |
| E R Beauty Limited | Other services | 2014 |
| E&W Property Ltd | Real estate | 2024 |
| E-Cig & Gadgets Ltd | Wholesale & retail | 2015 |
| E-Drago Media Ltd | Professional & scientific | 2020 |
| E.K.F. C.I.C. | Arts & recreation | 2025 |
| E.M. Trading Limited | Wholesale & retail | 2010 |
| E4 Structures Ltd | Manufacturing | 2010 |
| EAE Construction Ltd | Construction | 2021 |
| Eafield Services Limited | Construction | 2015 |
| Eagle Accountants Limited | Professional & scientific | 2018 |
| Eagle Approach Golf Ltd | Professional & scientific | 2024 |
| Eagle NW Installations Limited | Construction | 2018 |
| Eagle Travel and Convenience Limited | Wholesale & retail | 2024 |
| Eagles Rock Estate Limited | Construction | 2024 |
| Eaja Ltd | Real estate | 2025 |
| EAR Care Clinic NW Ltd | Health & social care | 2021 |
| Earlam IPS Limited | Construction | 2012 |
| Earth Life International Ltd | Wholesale & retail | 2024 |
| Earth Moving Components Ltd | Wholesale & retail | 2006 |
| Earth North West Limited | Administrative & support | 2016 |
| Ease Martuk Ltd | Wholesale & retail | 2026 |
| East and West Healthcare Limited | Health & social care | 2001 |
| East Anglia Trading Co Ltd | Administrative & support | 2013 |
| East Lancashire Refurbishments Limited | Other services | 2023 |
| East Lancashire Services Limited | Administrative & support | 1999 |
| Eastern European Travel Limited | Administrative & support | 1992 |
| Easy Compliance Ltd | Information & communication | 2019 |
| Easygift Logistics Ltd | Professional & scientific | 2019 |
| Easygift Trading Limited | Wholesale & retail | 2009 |
| Easyview Ltd | Wholesale & retail | 2025 |
| Easyyaa PVT Limited | Wholesale & retail | 2026 |
| EAT Fresh (NW) UK Ltd | Hospitality | 2012 |
| Eatwithmimi Ltd | Hospitality | 2026 |
| Eazideck Ltd | Construction | 2017 |
| Ebaiy Limited | Wholesale & retail | 2025 |
| Ebenazer Medical Limited | Health & social care | 2014 |
| Ebenezer Services Ltd | Health & social care | 2019 |
| Ebit Plus Ltd | Professional & scientific | 2022 |
| ECC Retail Ltd | Wholesale & retail | 2025 |
| Echo EKO Limited | Wholesale & retail | 2022 |
| Echo Finds Ltd | Wholesale & retail | 2025 |
| Eco Compact UK Ltd | Other services | 2025 |
| Eco Direct UK Ltd | Construction | 2025 |
| Eco Filter Services Ltd | Energy | 2019 |
| Eco Leaf Clean Ltd | Administrative & support | 2024 |
| Eco Nationwide Solutions Ltd | Administrative & support | 2025 |
| Eco Save Builders Limited | Construction | 2024 |
| Eco-Tech Plumbing Contractors Ltd | Construction | 2026 |
| Ecommbros Ltd | Wholesale & retail | 2024 |
| Ecomove Logistics Ltd | Transport & logistics | 2026 |
| Econna Commerce Ltd | Wholesale & retail | 2018 |
| Ecosight Limited | Wholesale & retail | 2026 |
| Ecovenn Courier Ltd | Transport & logistics | 2025 |
| Ecovisionmedia Ltd | Professional & scientific | 2026 |