| Spotted Frog Ltd | Professional & scientific | 2018 |
| Springleaf Commerce Limited | Wholesale & retail | 2018 |
| Spvalone Limited | Real estate | 2022 |
| Squeakie Clean Limited | Administrative & support | 2024 |
| SRI Lankan Art Escapes Ltd | Hospitality | 2020 |
| SRS Construction Consultancy Ltd | Professional & scientific | 2020 |
| ST Mark Homes PLC | Construction | 1999 |
| ST Pauls Garage Sobo Limited | Wholesale & retail | 2022 |
| ST. Quintin Avenue Residents Company Limited | Households | 1992 |
| Staines Metal Products (Group) Limited | Professional & scientific | 1958 |
| Stalbridge Developments Limited | Construction | 2001 |
| Stanley Gibbons Promotions | | 1981 |
| Stanleys Projects Ltd | Manufacturing | 2021 |
| Starks Electrical Ltd | Construction | 2021 |
| Starling Construction Solutions Ltd | Construction | 2023 |
| Station Gate Ringwood Management Company Limited | Real estate | 2018 |
| Stats Sports Limited | Information & communication | 1996 |
| Steel Piling Solutions Ltd | Professional & scientific | 2009 |
| Steels Wheels Ltd | Wholesale & retail | 2023 |
| Steelstone Property Ltd | Real estate | 2026 |
| Stenel Limited | Real estate | 2004 |
| Stephen Blythe Ltd | Professional & scientific | 2015 |
| Sterik Ltd | Arts & recreation | 2024 |
| Sterling Housing Construction Ltd | Construction | 2021 |
| Steve Palmer Building Limited | Construction | 2022 |
| Stewart Consultancy Limited | Professional & scientific | 2010 |
| Stewart Sales and Marketing Ltd | Administrative & support | 2010 |
| Stig Drilling Ltd | Administrative & support | 2019 |
| Storm Yacht Services Limited | Other services | 2017 |
| Stormbelt Ltd | Information & communication | 2014 |
| Story Abodes Ltd | Information & communication | 2018 |
| Stratasoft Ltd | Information & communication | 2014 |
| Strategic Data Management Solutions Ltd | Information & communication | 2016 |
| Streetley Properties Limited | Construction | 1976 |
| Streetwise Homes Limited | Construction | 2025 |
| Strictease Ltd. | Information & communication | 2007 |
| Strikes Bowling Limited | Arts & recreation | 2009 |
| Stroud Developments (Land) Ltd | Professional & scientific | 2018 |
| Stuart Mowlam Improvements Ltd | Construction | 2024 |
| Student Rental Homes Limited | Hospitality | 2016 |
| Studio Coast Ltd | Professional & scientific | 2026 |
| Studio Haasis LLP | | 2012 |
| Studiofifty Ltd | Real estate | 2019 |
| Studland Dene Freehold Limited | Real estate | 2018 |
| Stuntnuts Ltd | Arts & recreation | 2010 |
| Sturdyworks Ltd | Financial services | 2024 |
| Styleabbe Limited | Construction | 1981 |
| Subi Limited | Manufacturing | 2008 |
| Suction for Construction Limited | Extraterritorial | 2009 |
| Suds & Buds Ltd | Manufacturing | 2022 |
| SUE Lewis HR Consulting Ltd | Professional & scientific | 2008 |
| Sukuma Limited | Wholesale & retail | 2020 |
| Summerbreeze Cottages Ltd | Hospitality | 2020 |
| Summerhayes Residents Bournemouth Limited | Households | 2020 |
| Sun Connections Ltd | Education | 2019 |
| Sun Wash Ltd | Administrative & support | 2014 |
| Suncare Recovery Limited | Health & social care | 2007 |
| Sundeep Oravec Ltd | Health & social care | 2022 |
| Sunny Lyme Ltd | Hospitality | 2026 |
| Sunnyhurst Residents Association (Bournemouth) Limited | Households | 1979 |
| Sunrise Business Supplies Ltd | Wholesale & retail | 2024 |
| Sunset Landscapes Ltd | Administrative & support | 2025 |
| Sure Line Security Ltd | Administrative & support | 2025 |
| Surefire Events Ltd | Administrative & support | 2011 |
| Surefire Financial Planning Ltd | Financial services | 2019 |
| Surge Yachting Ltd | Administrative & support | 2026 |
| Sussex Inns Group Ltd | Hospitality | 2009 |
| Sussex Inns Properties Limited | Real estate | 2015 |
| Sussex Pubs and Clubs Ltd | Hospitality | 2020 |
| Swaffham Raceway Ltd | Arts & recreation | 2020 |
| Swains Hall Management Company Limited | Households | 1998 |
| Swanns Bookkeeping and Administration Services Ltd | Professional & scientific | 2023 |
| SWD Group Holdings Ltd | Financial services | 2021 |
| Sybils Burley Limited | Wholesale & retail | 2025 |
| Sydenham Scrap Metals Limited | Administrative & support | 2004 |
| Sylvaticus Limited | Information & communication | 2000 |
| Sylvester Restaurants Ltd | Hospitality | 2018 |
| SYM Logistics Ltd | Transport & logistics | 2026 |
| SYM Logistics UK & EU Ltd | Transport & logistics | 2024 |
| Sync Communications Limited | Professional & scientific | 2012 |
| Tabula Rasa Studios Ltd | Real estate | 2024 |
| Tache Crafts Limited | Information & communication | 2015 |
| Tailored Joinery Ltd | Manufacturing | 2024 |
| Tall Pines Limited | Real estate | 2017 |
| Tanning Studio KM Ltd | Other services | 2025 |
| Tano Limited | Hospitality | 2018 |
| Tao-X Limited | Real estate | 2021 |
| TAP Developments Ltd | Real estate | 2025 |
| Tascourt Limited | Real estate | 1984 |
| Taylor Grey Homes Ltd | Construction | 2011 |
| Taylor Properties Limited | Real estate | 1960 |
| Taylor Trading & Maintenance Limited | Real estate | 2016 |
| TB Projects Ltd | Real estate | 2007 |
| TCS Film Limited | Other services | 2017 |
| TCS Prime Roofing Ltd | Construction | 2023 |
| Technical Heating Limited | Construction | 2022 |
| Technical Writing Solutions Ltd | Wholesale & retail | 2023 |
| Teddy London Pets Ltd | Wholesale & retail | 2026 |
| Teeparty Ltd | Arts & recreation | 2019 |
| Tekbug IT Limited | Administrative & support | 2015 |