| DKA Investments Limited | Real estate | 1996 |
| DL Airtech Ltd | Construction | 2025 |
| DLC Refurbishment and Property Maintenance Limited | Construction | 2017 |
| DLM Mortgages Ltd | Financial services | 2021 |
| Dlw-Cs.Co.Uk (2017) Ltd | Information & communication | 2017 |
| Docdoc UK Limited | Arts & recreation | 2025 |
| Docklands Oven Cleaning Ltd | Administrative & support | 2025 |
| Doer Limited | Wholesale & retail | 2023 |
| Dolce Caffè & Restaurant Limited | Hospitality | 2017 |
| Dolce Passione Catering Ltd | Hospitality | 2022 |
| Domcrafted Garden Limited | Administrative & support | 2026 |
| Dominia Limited | Information & communication | 2025 |
| Dominion W13 Limited | Real estate | 2017 |
| Donkey Gate Management Company Limited | Professional & scientific | 1994 |
| DOT Excel Limited | Information & communication | 2022 |
| Down to Detail Home Ltd | Construction | 2025 |
| Downsize Made Easy Ltd | Real estate | 2023 |
| Doyle Capital Limited | Real estate | 2024 |
| DPV Properties Limited | Real estate | 2024 |
| DR Fotaki Biopharm Consulting Ltd | Professional & scientific | 2021 |
| DR Hannah Odendaal & Associates Ltd | Information & communication | 2022 |
| DR Lisa Wootton Ltd | Health & social care | 2017 |
| DR N J Bhuva Limited | Health & social care | 2017 |
| DR Neha Khade Limited | Health & social care | 2016 |
| DR1 Asset Management Ltd | Real estate | 2015 |
| DR127 Limited | Real estate | 2024 |
| Draxel AI Limited | Information & communication | 2026 |
| Drayton Green Properties Limited | Construction | 2021 |
| Dreamy GN Limited | Information & communication | 2022 |
| Dreo Solutions Ltd | Information & communication | 2025 |
| Drivesft Ltd | Transport & logistics | 2018 |
| Drjmcmedicalservices Ltd | Health & social care | 2016 |
| Drlisalifestylemedicine Limited | Health & social care | 2023 |
| Drmj Consulting Limited | Professional & scientific | 2013 |
| Drumsill Limited | Professional & scientific | 2021 |
| DS Hall Private & Corporate Investigations Limited | Administrative & support | 2008 |
| DSP Construction Consultants Ltd | Professional & scientific | 2024 |
| Dsquared Trading Limited | Administrative & support | 2020 |
| Duha Design Ltd | Construction | 2025 |
| Dunfly Trustee Limited | Extraterritorial | 1995 |
| Dunfly Trustee NO 2 Ltd | Arts & recreation | 2020 |
| Dunrossil IT Services Limited | Information & communication | 2025 |
| Duque & Archer E-Comm Group Ltd | Wholesale & retail | 2011 |
| Dutchie’S Jerk Joint Ltd | Hospitality | 2023 |
| Dv&K Engineering Ltd | Professional & scientific | 2022 |
| DW15 Limited | Real estate | 2024 |
| DW16 Limited | Real estate | 2025 |
| DXD Maintenance Ltd | Construction | 2024 |
| E a Hannigan Construction Services Limited | Professional & scientific | 2016 |
| E CIG City Spain Limited | Wholesale & retail | 2024 |
| E Hannigan Building Services Limited | Professional & scientific | 2008 |
| EA Crosse Associates Ltd | Professional & scientific | 2013 |
| Eagle Skip Ltd | Water & waste | 2025 |
| Ealing West Housing Limited | Construction | 2016 |
| EAR Care Mobile Limited | Health & social care | 2025 |
| Earth From Earth Ltd | Manufacturing | 2019 |
| East Lodge Lammas Limited | Real estate | 2024 |
| Eastbury Holdings Limited | Real estate | 2018 |
| Eastbury Homes Limited | Real estate | 2019 |
| Eastcote Hockey and Badminton Club Limited | Arts & recreation | 1996 |
| Easy Healing Limited | Health & social care | 2006 |
| Easy Weddings Limited | Other services | 2014 |
| Easytravel Agents Limited | Administrative & support | 2001 |
| Eaton Lodge Management Company Limited | Real estate | 2001 |
| Eazy Peazy Parties Limited | Hospitality | 2016 |
| Ebert Associates Ltd | Professional & scientific | 2013 |
| Ebiashara UK Ltd | Information & communication | 2024 |
| EBS Management Ltd | Hospitality | 2025 |
| Ecal Consultancy Limited | Construction | 2019 |
| Echo Creative Recovery Project CIC | Education | 2026 |
| Echo Golf Flying Ltd | Arts & recreation | 2018 |
| Eckos Holdings Limited | Real estate | 2018 |
| Eckos Properties Limited | Real estate | 2019 |
| Ecmr International Limited | Professional & scientific | 2011 |
| Eco Carpet Cleaning Company Ltd | Administrative & support | 2018 |
| Eco Glazing and Repairs Ltd | Construction | 2025 |
| Ecolyptix Ltd | Wholesale & retail | 2023 |
| ED Barkas Construction Ltd | Construction | 2022 |
| ED Medical Services Ltd | Health & social care | 2026 |
| EDA Property Limited | Real estate | 2023 |
| Eddy.Video Ltd | Information & communication | 2020 |
| Edge of the Forest Limited | Wholesale & retail | 2016 |
| Edge Recovery Limited | Professional & scientific | 2016 |
| Edgecot Limited | Hospitality | 2014 |
| Edgware MOT and Service Centre Limited | Wholesale & retail | 2008 |
| Edison Solutions Ltd | Construction | 2024 |
| Editions Musica Ferrum Ltd | Information & communication | 2019 |
| Educational and Careers Services Limited | Education | 2012 |
| EDW Accountancy Limited | Professional & scientific | 2009 |
| Edwards & New Limited | Information & communication | 2012 |
| Edwards Willoby & Loch Limited | Professional & scientific | 2017 |
| EEB Trading Ltd | Wholesale & retail | 2025 |
| Eebd Limited | Real estate | 2014 |
| EEN Group UK Limited | Information & communication | 2006 |
| Efficiency Through Tech Limited | Information & communication | 2017 |
| Egroup P&I Limited | Real estate | 2016 |
| Egurus Limited | Professional & scientific | 2008 |
| Egyptian A.E.For Sports Investment Limited | Education | 2023 |
| EH 2 Ltd | Real estate | 2022 |
| EH4 Ltd | Real estate | 2024 |