| Emolyne Interiors Limited | Professional & scientific | 2021 |
| Empire South Limited | Real estate | 1996 |
| Emre Turkish Barber Ltd | Other services | 2019 |
| EMS Education Marketing Specialists Limited | Professional & scientific | 2022 |
| EMS Fisico Limited | Arts & recreation | 2019 |
| Enclaver Labs Ltd | Information & communication | 2016 |
| Encore Music Tuition Limited | Education | 2013 |
| Endacott Limited | Professional & scientific | 1987 |
| Endless Global Ltd | Professional & scientific | 2021 |
| Energy CRU Ltd | Administrative & support | 2022 |
| Energy Management Consultancy Limited | Professional & scientific | 2015 |
| Energy Tailored Solutions Ltd | Professional & scientific | 2026 |
| ENG 28 Limited | Real estate | 2020 |
| Engcode Limited | Wholesale & retail | 2018 |
| Engineer Stillness Ltd | Wholesale & retail | 2025 |
| Engineering Detail Services Limited | | 1967 |
| Engineering Projects Protechnology Ltd | Construction | 2011 |
| Englore Limited | Information & communication | 2022 |
| Engserv Power Limited | Professional & scientific | 2013 |
| Engys Ltd | Information & communication | 2009 |
| Enhance Property Maintenance Specialists Limited | Construction | 2003 |
| Enise Limited | Administrative & support | 2006 |
| Enngie Ltd | Administrative & support | 2017 |
| Enrich Community Volunteering Ltd | Administrative & support | 2024 |
| Enterprise Commodity Services Limited | Administrative & support | 2007 |
| Enterprise Service Management Holding Ltd | Real estate | 2025 |
| Eotb Ltd | Other services | 2023 |
| EPG (UK) Ltd | | 2011 |
| Epic North Ltd | Professional & scientific | 2026 |
| Epic Relocation Limited | Real estate | 2001 |
| Epicardio Ltd | Information & communication | 2011 |
| Epiccuro (Central Europe) Property Fund | | 2007 |
| Epicurean Larder Ltd | Wholesale & retail | 2025 |
| EPM Tree Services Limited | Agriculture & fishing | 2025 |
| Eporter Limited | Wholesale & retail | 2014 |
| Epsom Properties Limited | Financial services | 2014 |
| Eqinics Ltd | Wholesale & retail | 2019 |
| Equestrian Bookfair Ltd | Wholesale & retail | 2006 |
| Equinox Creative Ltd | Information & communication | 2023 |
| Equiture Real Estate Capital Limited | Real estate | 2009 |
| ER Expert Ltd | Professional & scientific | 2014 |
| ERA Acoustics Limited | Manufacturing | 2012 |
| ES Media Ltd. | Professional & scientific | 2010 |
| Escape 2 Richmond Limited | Hospitality | 2018 |
| Escape England Limited | Hospitality | 2025 |
| Escape Velocity Ventures Ltd | Information & communication | 1998 |
| Eskimo Latino Films Ltd | Information & communication | 2011 |
| Esme Ellie Limited | Information & communication | 2025 |
| Espoir Property Limited | Real estate | 2018 |
| Espresso 10 Limited | Hospitality | 2015 |
| Esquire Barber Shop (Richmond) Limited | Other services | 2014 |
| Essencia Homes Tetbury LLP | | 2013 |
| Essential Care Homecare Limited | Administrative & support | 2024 |
| Established Today Ltd | Professional & scientific | 2024 |
| Estafet Limited | Information & communication | 2002 |
| Estate Holdings Ltd | Financial services | 2024 |
| Estates Securities & Asset Management (Commercial) Limited | Real estate | 2020 |
| Estates Securities and Asset Management (Freehold) Limited | Real estate | 2019 |
| Estates Securities and Asset Management (Hastings) Ltd | Real estate | 2017 |
| Estates Securities and Asset Management Limited | Real estate | 2008 |
| Etaca Limited | Manufacturing | 2026 |
| Eternity D8A Ltd | Information & communication | 2025 |
| Etherington Properties Limited | Real estate | 2022 |
| Ethic Trading & Sustainability Limited | Administrative & support | 2019 |
| Ethicoil Limited | Manufacturing | 2020 |
| Ethnographic Enterprises Ltd | Real estate | 2012 |
| Eton ROW Consultancy Limited | Professional & scientific | 2016 |
| Eton ST Groomers Ltd | Agriculture & fishing | 2023 |
| Eurodebt Recovery Limited | Financial services | 1998 |
| Europe Adventures Ltd | Administrative & support | 2014 |
| European Satellite Systems Limited | | 1990 |
| EVE Marina, Sociedad Limitada | | 2006 |
| Event Digital Limited | Information & communication | 2013 |
| Event Medical Cover LLP | | 2023 |
| Event-Source Limited | Professional & scientific | 2004 |
| Eventure VA Limited | Professional & scientific | 2016 |
| Evergreen Property Management (North East) Limited | Real estate | 2024 |
| Everlong Holdings Limited | Financial services | 2018 |
| Every Home for Christ | Other services | 1982 |
| Everyriver Atlas Limited | Information & communication | 2025 |
| Evolve Architectural Services Limited | Professional & scientific | 2006 |
| Evra Services Ltd | Transport & logistics | 2020 |
| Evtech Engineering Ltd | Real estate | 2011 |
| Exasol UK Limited | Information & communication | 2014 |
| Excellence Properties Limited | Real estate | 2004 |
| Excelsior Security Trustee Limited | Other services | 2022 |
| Excelsource Limited | Professional & scientific | 2008 |
| Exclusive Aviation Limited | Transport & logistics | 2002 |
| Exclusive Golf Tours Limited | Professional & scientific | 2008 |
| Exclusive Travel Group Ltd | Administrative & support | 2025 |
| Exclusive Wine Import UK Limited | Wholesale & retail | 2021 |
| Excluss Ltd | Energy | 2010 |
| Exec-Va Limited | Administrative & support | 2024 |
| Executive Lifestyle Letting Limited | Real estate | 2004 |
| Exhaust a FIX Ltd | Wholesale & retail | 2003 |
| Expect Amazing Ltd | Wholesale & retail | 2018 |
| Expendium Ltd | Information & communication | 2012 |
| Expertsy Limited | Information & communication | 2023 |
| Export Office Solutions Ltd | Administrative & support | 2015 |
| Express Installers Ltd | Construction | 2020 |