| Shawhire Limited | Agriculture & fishing | 2000 |
| Sheetfed Holdings Limited | Wholesale & retail | 2012 |
| Shelley Administration Services Ltd | Professional & scientific | 2023 |
| Shelleys Taxis Limited | Transport & logistics | 2010 |
| Shepston Planning Limited | Construction | 2023 |
| Sherwood Hire Services Ltd | Professional & scientific | 2009 |
| Sherwood Inns Limited | Administrative & support | 2001 |
| Sherwood Longbow Ltd | Real estate | 2024 |
| Sherwood Paws Limited | Wholesale & retail | 2024 |
| Shining Sunder Solutions Limited | Information & communication | 2025 |
| Shires Marquees Ltd | Administrative & support | 2022 |
| Shluxuryescapes Ltd | Real estate | 2026 |
| Shoes GB (Bawtry) Limited | Wholesale & retail | 2025 |
| Shweta & Krithiks Properties Ltd | Real estate | 2024 |
| SI DSL Limited | Professional & scientific | 2020 |
| Siffrorna Technology Limited | Professional & scientific | 2017 |
| Sigassure UK Limited | Construction | 2008 |
| Silva Correia Consultancy Limited | Administrative & support | 2011 |
| Silver Pound Plus Ltd | Wholesale & retail | 2023 |
| Silverrose Property Services Ltd | Real estate | 2025 |
| Simply Car Parts Limited | Wholesale & retail | 2017 |
| Simply Hair Limited | Wholesale & retail | 2014 |
| Simply Insurance Services Limited | Financial services | 2000 |
| Simular Limited | Extraterritorial | 2017 |
| Sinobrit Easyship International Trading Co. Ltd | Wholesale & retail | 2024 |
| Sisi Events Ltd | Hospitality | 2024 |
| SIX Oaks Capital LLP | | 2025 |
| SIX Oaks Financial Services LLP | | 2023 |
| SIX Oaks Properties LLP | | 2022 |
| SIX Solutions Ltd | Construction | 2004 |
| SIXTYSIX70 Limited | Information & communication | 2020 |
| SJ Fit Coaching Ltd | Education | 2023 |
| SJ Hannah Ltd | Hospitality | 2020 |
| SJE Signals Ltd | Professional & scientific | 2010 |
| Sjes Farming Ltd | Agriculture & fishing | 2014 |
| SKD Technical Ltd | Professional & scientific | 2007 |
| Sklk Property Limited | Real estate | 2025 |
| Skypoint Horizon Ltd | Real estate | 2021 |
| SL Training Ltd | Education | 2018 |
| SLH Medical Limited | Health & social care | 2022 |
| Smart Electrical and Heating Solutions Ltd | Construction | 2023 |
| Smart Link 101 Ltd | Information & communication | 2025 |
| Smba Group Ltd | Administrative & support | 2022 |
| Smith Farms Limited | Agriculture & fishing | 2017 |
| Smith Hall Events Ltd | Hospitality | 2018 |
| Smith Property Limited | Real estate | 2014 |
| Smith XYZ Limited | Extraterritorial | 2014 |
| Snap Ltd | Wholesale & retail | 1996 |
| Snape Lane Property LLP | | 2021 |
| Snug Investments Limited | Real estate | 2014 |
| Snug Newco One Limited | Extraterritorial | 2014 |
| Snug Newco Two Limited | Extraterritorial | 2014 |
| Snug Property Limited | Extraterritorial | 2011 |
| Softalk (Retford) Limited | Information & communication | 2002 |
| Softalk Limited | Information & communication | 2021 |
| Solarnet Solutions Ltd | Construction | 2025 |
| Solent GB Developments (AG) Ltd | Construction | 2018 |
| Songo Healthcare Limited | Health & social care | 2021 |
| Sophia Property Development Limited | Construction | 2014 |
| Soul Good Stuff Ltd | Wholesale & retail | 2019 |
| Soup Shop Productions Ltd | Manufacturing | 2019 |
| Soyo Design and Marketing Ltd | Professional & scientific | 2022 |
| Spa at YE Olde Bell Limited | Arts & recreation | 2017 |
| Space at the Lake Ltd | Real estate | 2026 |
| Space Cadets Childminders Ltd | Health & social care | 2023 |
| Spear Technology Limited | Information & communication | 2010 |
| Specialised Metal Processors Ltd | Manufacturing | 2018 |
| Specialised Operations Ltd | Extraterritorial | 2011 |
| Specky’S Emporium Ltd | Wholesale & retail | 2023 |
| Speirs Performance Ltd | Other services | 2020 |
| Sporting Cuts Barbers Ltd | Other services | 2025 |
| Spurr Drilling Ltd | Administrative & support | 2025 |
| Spurr Geotechnical Limited | Construction | 2010 |
| Squiggles Nursery Ltd | Health & social care | 2025 |
| Squiggles Playden (Retford) Ltd | Arts & recreation | 2024 |
| SSS Safety Limited | Professional & scientific | 2019 |
| ST Augustines Mews Management Company | Real estate | 2024 |
| ST Giles Holdings (Number 1) Limited | Financial services | 2001 |
| ST Giles Holdings (Number 2) Limited | Financial services | 2019 |
| ST Giles International Limited | Financial services | 1983 |
| ST Luke Underwriting Ltd. | Financial services | 2016 |
| ST. Giles Insurance & Finance Services Limited | Financial services | 1972 |
| STA Home Furnishings Limited | Wholesale & retail | 2017 |
| STA Upholstery Limited | Manufacturing | 2018 |
| Stacey Jones Interpreting Ltd | Professional & scientific | 2024 |
| Stafford Crest Eco Farm Limited | Energy | 2023 |
| Stanem Ltd | Other services | 2022 |
| Star & Sundarajan Limited | Health & social care | 2022 |
| Star 1 Service Limited | Manufacturing | 2007 |
| Steingold Associates Limited | Information & communication | 2007 |
| Steingold LG Ltd | Extraterritorial | 2011 |
| Stenton Shortt Ltd | Manufacturing | 2022 |
| Sterling Grid Security Ltd | Manufacturing | 2025 |
| Steve Howard (Farms) Ltd | Agriculture & fishing | 1976 |
| Steve Mechanical Limited | Construction | 2011 |
| Steven Smith Welding Services Ltd | Manufacturing | 2014 |
| Stoke Fields Limited | Real estate | 2024 |
| Stonelake Lodges Ltd | Hospitality | 2024 |
| Store IT (Ollerton) Limited | Transport & logistics | 2025 |
| Stored Energy Solutions Ltd | Professional & scientific | 2024 |