| Selcam Services Ltd | Administrative & support | 2010 |
| Sels Property Ltd | Real estate | 2026 |
| Sensory Surge Ltd | Wholesale & retail | 2024 |
| Sequitur Risk Ltd | Financial services | 2019 |
| Serendipity Health & Beauty (Merstham) Ltd | Other services | 2020 |
| Serrae Ltd | Wholesale & retail | 2020 |
| Servanto Group Ltd | Construction | 2025 |
| Service Plus (Redhill) Limited | Wholesale & retail | 1995 |
| Serviceminds Ltd | Information & communication | 2025 |
| Servit Systems Limited | Information & communication | 1998 |
| SES Home Services Limited | Extraterritorial | 2016 |
| SES Water Limited | Water & waste | 2016 |
| Sessions Radio Ltd | Information & communication | 2025 |
| Setl Group Ltd | Financial services | 2019 |
| Setl Homes (Massetts Road) Ltd | Real estate | 2023 |
| Setl Homes Ltd | Real estate | 2019 |
| Setplan Limited | Professional & scientific | 1997 |
| Sevex Maintenance Ltd | Construction | 2024 |
| Sevex Telecommunications Ltd | Information & communication | 2022 |
| SG Yachting Ltd | Information & communication | 2018 |
| SGD (UK) Limited | Manufacturing | 2002 |
| Sge-Services Holdings Ltd | Financial services | 2024 |
| Sge-Services Ltd | Construction | 2011 |
| SGK Mortgages Limited | Financial services | 2026 |
| Shake &Twist Rumba Limited | Wholesale & retail | 2022 |
| Shamari Ltd | Arts & recreation | 2024 |
| Shane Keens Renovations Limited | Construction | 2008 |
| Shannon Way Freehold Ltd | Households | 1999 |
| Sharoxin Ltd | Construction | 2025 |
| Shearer's Fine Foods Limited | Wholesale & retail | 2013 |
| Shelby Property Solutions Ltd | Construction | 2022 |
| Sherlock Funeral Service Limited | Other services | 2009 |
| Sherman Finance & Properties Limited | Real estate | 2002 |
| Shimento Ltd | Information & communication | 2025 |
| Shine Education and Training Ltd | Professional & scientific | 2016 |
| Shine With ME Cleaning Services Ltd | Administrative & support | 2020 |
| Ship Concept Consulting Limited | Transport & logistics | 2014 |
| Shippo Limited | Transport & logistics | 2009 |
| Shkaa Consulting Ltd | Education | 2019 |
| Shopper Insight (Southern) Ltd | Professional & scientific | 2022 |
| Shopper Insight Limited | Professional & scientific | 2011 |
| Shoreham Aviation Flight Centre Ltd | Manufacturing | 2021 |
| Shorestone Financial LLP | | 2008 |
| Showrun Limited | Information & communication | 2025 |
| Shuttl ME Limited | Transport & logistics | 2024 |
| Shuttle Learning Ltd | Education | 2024 |
| Shuvo Ltd | Hospitality | 2019 |
| Sifa Space Ltd | Information & communication | 2026 |
| Sigma Property and Developments Limited | Real estate | 2024 |
| Signs & Safety Limited | Administrative & support | 2001 |
| Silencieux Limited | Wholesale & retail | 2023 |
| Silhouette Creatives Ltd | Professional & scientific | 2017 |
| Silver Birch 2 Limited | Real estate | 2024 |
| Silver Birch Property Developments Limited | Real estate | 2023 |
| Silver Pelican Entertainment Ltd | Arts & recreation | 2021 |
| Silvermere Court Freeholders Limited | Households | 2018 |
| Simon Attridge Bespoke Ltd | Hospitality | 2026 |
| Simple Talking Ltd | Education | 2023 |
| Simplified Signals Limited | Information & communication | 2020 |
| Simpsons (Mortgage Services) Limited | Administrative & support | 1992 |
| Simpsons Estate Agents (West Byfleet) Limited | Real estate | 2022 |
| Simpsons Estate Agents (Woking) Limited | Real estate | 1991 |
| Simpsons Estate Agents Limited | Real estate | 1989 |
| Singular Software Limited | Manufacturing | 2019 |
| SIP & YAP Ltd | Hospitality | 2025 |
| Sitescast Ltd | Real estate | 2025 |
| SJ Dreams Ltd | Real estate | 2025 |
| SJ Oliver Limited | Professional & scientific | 2025 |
| SJB Felcourt Consulting Ltd | Professional & scientific | 2018 |
| SJD Window Cleaning Services Ltd | Administrative & support | 2025 |
| SJM Roofing Limited | Construction | 2016 |
| SJT Accounting Solutions Ltd | Professional & scientific | 2017 |
| SJW ENG Tech Ltd | Professional & scientific | 2023 |
| Skava Aviation Ltd | Transport & logistics | 2025 |
| Skinner and Howes Group Ltd | Construction | 2026 |
| Skinsense Ltd | Wholesale & retail | 2017 |
| SKM Builders Ltd | Construction | 2019 |
| Sky FLY Cars Ltd | Transport & logistics | 2019 |
| Skylarks Fmqs Ltd | Professional & scientific | 2017 |
| Slabtastic Ltd | Construction | 2019 |
| Sladey Management Services Limited | Wholesale & retail | 2014 |
| Slimsd Ltd | Hospitality | 2018 |
| Slingshot Ventures Limited | Wholesale & retail | 2025 |
| Slinkies Events Limited | Administrative & support | 2014 |
| Slipstream Integrations Ltd | Construction | 2026 |
| SLN Real Estates Ltd | Real estate | 2025 |
| Slow Steps Housing Ltd | Real estate | 2025 |
| Slow Steps Limited | Health & social care | 2025 |
| Slph Limited | Households | 1998 |
| SLR Accounting Services Ltd | Professional & scientific | 2019 |
| SLS Lifts Ltd | Hospitality | 2004 |
| SM Business Consultancy Limited | Professional & scientific | 2026 |
| Small Property Ltd | Extraterritorial | 2013 |
| Smallfield 1817 Ltd | Real estate | 2026 |
| Smart Choice Home Decorating Ltd | Construction | 2026 |
| Smart Design SD Ltd | Manufacturing | 2022 |
| Smarteezie Ltd | Information & communication | 2009 |
| Smartfix Maintenance Ltd | Construction | 2024 |
| Smilde Food Group Ltd | Wholesale & retail | 1961 |
| Smile Tours SRI Lanka Ltd | Administrative & support | 2025 |