| Peart Accounting Ltd | Professional & scientific | 2020 |
| Pegasus Industrial Coatings Ltd | Construction | 2014 |
| Peggy Junes Ltd | Hospitality | 2023 |
| Peony Nails Spa and Beauty Limited | Other services | 2026 |
| Peptigen Ltd | Professional & scientific | 2025 |
| PGM Investments Ltd | Real estate | 2014 |
| PGM Property Services Ltd | Real estate | 2024 |
| PH Services NE Limited | Construction | 2022 |
| Phases Psychotherapy Ltd | Professional & scientific | 2025 |
| PHX Health & Wellbeing Ltd | Arts & recreation | 2025 |
| PIA Holdings (North East) Limited | Financial services | 2021 |
| PIA Partners (Land) Limited | Real estate | 2021 |
| PIA Partners Limited | Real estate | 2021 |
| Pibble Limited | Real estate | 2022 |
| Pikachu Pizza Ltd | Hospitality | 2024 |
| Pimm's and Needles East Coast CIC | Other services | 2023 |
| Pink Light District Ltd | Wholesale & retail | 2025 |
| PIP Teesside Ltd | Real estate | 2025 |
| Pipeline Testing Services Ltd | Professional & scientific | 2021 |
| Pitch 12 Limited | Real estate | 2024 |
| Pitchno 12 Fairs Ltd | Wholesale & retail | 2025 |
| PITCHNO.12 Limited | Wholesale & retail | 2023 |
| Pizza Pronto Redcar One Ltd | Hospitality | 2025 |
| PJB (Saltburn) Ltd | Health & social care | 2010 |
| Pjsmj Ltd | Administrative & support | 2018 |
| PKT Recruitment Ltd | Administrative & support | 2025 |
| Plantation Health & Safety Services Ltd | Other services | 2019 |
| Plis Group Ltd | Construction | 2024 |
| Plume Biotechnology Limited | Professional & scientific | 2021 |
| PM Rees & Sons 2000 Limited | Transport & logistics | 2000 |
| PMQ Offshore Services Ltd | Professional & scientific | 2026 |
| PMS Business Solutions Ltd | Wholesale & retail | 2025 |
| Portecass Properties Ltd | Real estate | 2023 |
| Positive Mindset Coaching & Wellbeing CIC | Health & social care | 2025 |
| Positive Mindset Coaching Ltd | Financial services | 2024 |
| Poulter Homes Limited | Real estate | 2017 |
| Poulter Property Services Ltd | Real estate | 2018 |
| Power Cleanse Ltd | Administrative & support | 2022 |
| Prestige Northern Limited | Administrative & support | 2020 |
| Preston Property Solutions Ltd | Real estate | 2021 |
| Pretty Little Spa Ltd | Other services | 2022 |
| Pretty Whiskers Limited | Other services | 2025 |
| Prim and Proper Events Limited | Administrative & support | 2016 |
| Prime 39 Limited | Real estate | 2021 |
| Prime Hide Exports Ltd | Wholesale & retail | 2026 |
| Primo Construction Services Limited | Construction | 2024 |
| Principal Lettings Limited | Real estate | 2022 |
| Pristine 2 Clean Ltd | Administrative & support | 2025 |
| Prjp Electrical Limited | Construction | 2015 |
| Pro Property Investment & Management Ltd | Real estate | 2023 |
| Pro-Fit Property Services Limited | Construction | 2021 |
| Probitas Occupational Health Limited | Health & social care | 2015 |
| Process Engeering Services Ltd | Professional & scientific | 2026 |
| Products Sourcing Ltd | Wholesale & retail | 2019 |
| Professional Aviation Solutions Ltd | Transport & logistics | 2017 |
| Professional Contracting Services Limited | Energy | 2016 |
| Project Design North East Limited | Professional & scientific | 2016 |
| Project Escape (Hexham) Limited | Arts & recreation | 2021 |
| Project Escape Ltd | Arts & recreation | 2018 |
| Prolific Events Limited | Administrative & support | 2025 |
| Prometheus Pathways Limited | Health & social care | 2026 |
| Property Investment & Lettings Company Ltd | Real estate | 2023 |
| Property Professionals North East Limited | Real estate | 2024 |
| Propgevity Investments Ltd | Real estate | 2025 |
| Propgevity Sourcing Ltd | Real estate | 2026 |
| Propgevity Surveys Ltd | Real estate | 2024 |
| Proscaffoldingspecialistuk Ltd | Construction | 2025 |
| Prvan Ltd | Real estate | 2020 |
| PT Kitchens Ltd | Manufacturing | 2023 |
| Putson Electrical Services Ltd | Manufacturing | 2015 |
| PV Circle Point LLP | | 2020 |
| Pybus Heavy Lifting Ltd | Construction | 2025 |
| Qarbon Timber Ltd | Financial services | 2022 |
| QS1 Ltd | Real estate | 2021 |
| Queens Guard Working Dogs Ltd | Administrative & support | 2022 |
| Quickfix Mobiles & Vapes Ltd | Wholesale & retail | 2022 |
| R Bevan Plumbing and Heating Limited | Construction | 2026 |
| R HAM Holdings Limited | Mining & quarrying | 2022 |
| R Watt Lifting & Rigging Ltd | Construction | 2025 |
| R&J Exterior Cleaning Ltd | Administrative & support | 2026 |
| Raby Properties Limited | Financial services | 2023 |
| Race Refinish Ltd | Wholesale & retail | 2015 |
| Radical Labs Ltd | Administrative & support | 2018 |
| Radio Tees Limited | Information & communication | 2024 |
| Rage Against the Cuisine Limited | Hospitality | 2017 |
| Rainbow Promise North East and Yorkshire CIC | Hospitality | 2023 |
| Ramp Training Group Ltd | Administrative & support | 2025 |
| Ransom Property Limited | Real estate | 2024 |
| Ransome Properties Ltd | Real estate | 2019 |
| Rapid Build JTG Limited | Real estate | 2016 |
| RAW Graft Ltd | Construction | 2025 |
| RAY Robinson Limited | Manufacturing | 2016 |
| Raymond Clark Building Services Ltd | Construction | 2023 |
| RCE (NE) Ltd | Construction | 2023 |
| RD Design & Legal Ltd | Professional & scientific | 2022 |
| RDW Driving Ltd | Education | 2018 |
| Ream Cleaning Services Ltd | Administrative & support | 2019 |
| Ream Clothing UK Ltd | Wholesale & retail | 2022 |
| Rebalance Group Ltd | Professional & scientific | 2026 |
| Recrutatio Limited | Administrative & support | 2025 |