| Rtssom Limited | Education | 2024 |
| Rubbish Clearance Essex Limited | Water & waste | 2013 |
| Rubbish Master Ltd | Water & waste | 2022 |
| Rubek Construction Limited | Construction | 2018 |
| Rubi UK Limited | Manufacturing | 2004 |
| Rubix Cube Limited | Wholesale & retail | 2017 |
| Ruby Saffron Ltd | Information & communication | 2022 |
| Rurans Engineering Ltd | Wholesale & retail | 2025 |
| Russbridge Academy Ltd | Education | 2019 |
| Rwtt Ltd | Wholesale & retail | 2025 |
| Ryan Group of Companies Ltd | Administrative & support | 2019 |
| S & D Components Limited | Wholesale & retail | 2005 |
| S & J'S Cleaning Service Limited | Administrative & support | 2026 |
| S & K Plumbing and Heating Ltd | Energy | 2017 |
| S & M Investment Group Ltd | Real estate | 2025 |
| S Amodu Limited | Hospitality | 2025 |
| S Biko Tech Consults Ltd | Professional & scientific | 2024 |
| S J Monk Plumbing & Heating Ltd | Construction | 2014 |
| S Oware Ltd. | Health & social care | 2022 |
| S S Gill Holdings Ltd | Financial services | 2025 |
| S Sumit Constructions Limited | Construction | 2020 |
| S&B Contractors Ltd | Construction | 2026 |
| S&S Accountant Ltd | Financial services | 2018 |
| S&S Carer Ltd | Health & social care | 2025 |
| S&T Reliance Limited | Real estate | 2022 |
| S.A.I. Home Improvements Ltd | Wholesale & retail | 1996 |
| S.L Care Limited | Health & social care | 2025 |
| S.M.S Scaffolding Ltd | Construction | 2023 |
| S.Spahair Ltd | Other services | 2024 |
| S.W.E.T.A | Education | 2014 |
| S6 Homes Ltd | Real estate | 2022 |
| SA Ecommerce Services Ltd | Wholesale & retail | 2023 |
| SA Global Group Ltd | Financial services | 2026 |
| Saaap Ltd | Real estate | 2021 |
| Sabanor Limited | Health & social care | 2026 |
| Sabaruh UK Limited | Professional & scientific | 2025 |
| Sabe Bathrooms Limited | Manufacturing | 2025 |
| Sabharwal Property Management Ltd | Real estate | 2025 |
| Sabio Confidence Coaching Ltd | Professional & scientific | 2025 |
| Sadeola Limited | Health & social care | 2016 |
| Sadhra Property Ltd | Construction | 2021 |
| SAF Building Services Ltd | Construction | 2019 |
| SAF Tutoring Limited | Education | 2026 |
| Safe Homes Maintenance Ltd | Construction | 2025 |
| Safety Assured Limited | Manufacturing | 2001 |
| Sahota Housing Ltd | Real estate | 2023 |
| Sahota Legacy Developments Ltd | Financial services | 2025 |
| Sahota Rentals Ltd | Real estate | 2023 |
| Saint Products Ltd | Wholesale & retail | 2022 |
| Sajux Ltd | Wholesale & retail | 2023 |
| Salem 24/7 Limited | Health & social care | 2025 |
| Salivan Payments Limited | Financial services | 2026 |
| Saliwa Investments Ltd | Health & social care | 2024 |
| Salt and Stone Construction Ltd | Construction | 2024 |
| Salyan Construction Ltd | Construction | 2025 |
| Salyan Logistics Ltd | Transport & logistics | 2025 |
| SAM Property Lettings Ltd | Real estate | 2025 |
| Sam-Jordan Ltd | Other services | 2016 |
| Samallure Care Limited | Health & social care | 2024 |
| Samieul Consulting Ltd | Professional & scientific | 2017 |
| Sampon Limited | Health & social care | 2020 |
| Samratareq Ltd | Professional & scientific | 2021 |
| Sams Davis Property Management Ltd | Real estate | 2021 |
| Sams Yard Limited | Water & waste | 2012 |
| Samsani Medical Services Limited | Health & social care | 2015 |
| Samuel Bishop Ltd | Professional & scientific | 2018 |
| Samuel Court Leasehold Management Ltd | Households | 2026 |
| Sanah H Homes Ltd | Real estate | 2025 |
| Sancturio Medico Ltd | Health & social care | 2020 |
| Sara's Welfare Trust CIC | Other services | 2025 |
| Sard Property Ltd | Real estate | 2024 |
| Sariyu Space and Entertainment Ltd | Hospitality | 2024 |
| Sarker and Co UK Ltd | Hospitality | 2018 |
| Savane Property Services Limited | Real estate | 2025 |
| Saver's Utility Limited | Administrative & support | 2016 |
| Sawayone Limited | Administrative & support | 2024 |
| Sawise Limited | Administrative & support | 2024 |
| Sazeda Properties Limited | Real estate | 2023 |
| SB & a (UK) Ltd | Manufacturing | 2008 |
| SBB Logistics Limited | Transport & logistics | 2022 |
| SBH Contracting Limited | Construction | 2016 |
| School of Bionatural Medicine Ltd | Education | 2022 |
| Scott Dunn Publishing Limited | Information & communication | 2021 |
| SCS Costs Services Ltd | Professional & scientific | 2019 |
| SDB Consulting Ltd | Financial services | 2024 |
| SDQ Capital Ltd | Professional & scientific | 2025 |
| SDQ Properties Ltd | Administrative & support | 2017 |
| SE Naamoragh Ltd | Professional & scientific | 2026 |
| Seafarers Logistics GB Ltd | Transport & logistics | 2017 |
| Seamco UK Ltd | Transport & logistics | 2026 |
| Secure Gateways Ltd | Construction | 2026 |
| Secure Heating Limited | Construction | 2026 |
| Secured Zones Consulting Ltd | Information & communication | 2019 |
| Secures Care Services Ltd | Other services | 2019 |
| SECURI365 Limited | Administrative & support | 2024 |
| Security Projects Facilities Management Ltd | Administrative & support | 2018 |
| Security Projects UK Ltd | Administrative & support | 2009 |
| Seema Barua Ltd | Health & social care | 2026 |
| Sefannah UK Limited | Health & social care | 2018 |
| Sela Commercials Ltd | Wholesale & retail | 2018 |