| Dormie 1 Ltd | Wholesale & retail | 2024 |
| Dorset Emergency Services PPP (Holdings) Limited | Professional & scientific | 2007 |
| Doru Sorcoiu Ltd | Transport & logistics | 2026 |
| Dose Design and Marketing Ltd | Information & communication | 2014 |
| DOT Executive Partners Limited | Real estate | 2025 |
| DOT Recruit Limited | Administrative & support | 2019 |
| Dothework Academy Ltd | Education | 2024 |
| Dotty Lines Limited | Other services | 2000 |
| Double Hammer Engineering Ltd | Professional & scientific | 2013 |
| Double JAY Properties Limited | Real estate | 2020 |
| Double O Developments Limited | Real estate | 2025 |
| Dough BOY Events Ltd | Wholesale & retail | 2021 |
| Dough BOY Weddings Limited | Hospitality | 2023 |
| Dough Delight Ltd | Hospitality | 2026 |
| Douglas Installations Limited | Professional & scientific | 2015 |
| Douglas Marine Limited | Manufacturing | 2021 |
| Douglass Walker Financial Management Limited | Professional & scientific | 2001 |
| Dove Commercial Properties Limited | Households | 2018 |
| Dovetail Joinery (Preston) Limited | Construction | 2004 |
| DOW Medicose Limited | Health & social care | 2010 |
| Dowbridge Limited | Financial services | 1971 |
| Dowlingj Ltd | Construction | 2026 |
| Down to Earth Electrics Limited | Construction | 2003 |
| Downtown Food and Drink Limited | Hospitality | 2018 |
| Downtown in Business Group Limited | Professional & scientific | 2023 |
| Doyoo Enterprise Ltd | Wholesale & retail | 2020 |
| DP Bars Ltd | Hospitality | 2021 |
| DP Property Renovations Ltd | Construction | 2020 |
| DP Steel Limited | Construction | 2021 |
| DP. Data Pulse Ltd | Professional & scientific | 2025 |
| Dpaero Ltd | Administrative & support | 2019 |
| DPF Sales Limited | Wholesale & retail | 2021 |
| Dphold Limited | Other services | 2016 |
| DPL Air Conditioning Services Limited | Construction | 2008 |
| DPN Devolpments Ltd | Construction | 2026 |
| DR a Ehsan Medical Services Limited | Health & social care | 2026 |
| DR ALI Foundation | Health & social care | 2022 |
| DR AS Medicals Limited | Health & social care | 2024 |
| DR B Juwaied Medical Services Limited | Health & social care | 2023 |
| DR C P Johnson Limited | Administrative & support | 2009 |
| DR DOM Services Ltd | Health & social care | 2024 |
| DR Eamonn Molloy Ltd | Professional & scientific | 2018 |
| DR FAY Townsend Holdings Ltd | Financial services | 2025 |
| DR G N Jones Limited | Health & social care | 2012 |
| DR Jekyll and MR Hyde Limited | Manufacturing | 2020 |
| DR Katy Knight Aesthetics Limited | Other services | 2025 |
| DR Klinisch Private Limited | Health & social care | 2024 |
| DR Lashein's Limited | Health & social care | 2023 |
| DR Linda GP Services Ltd | Health & social care | 2024 |
| DR M Munavvars Limited | Health & social care | 2019 |
| DR Martin's Aesthetics Ltd | Health & social care | 2024 |
| DR Nabeel Essa Limited | Wholesale & retail | 2020 |
| DR R a Mccahon Limited | Health & social care | 2014 |
| DR R Mason Medical Services Limited | Health & social care | 2026 |
| DR SDV Shaunak Limited | Health & social care | 2012 |
| DR Thiess Ltd | Health & social care | 2022 |
| DR Vineet JP Ltd | Health & social care | 2024 |
| DR Yaqub Limited | Health & social care | 2023 |
| DR. Katie Ashcroft Ltd | Health & social care | 2013 |
| DR. SS Aesthetics & Cosmetics Ltd | Health & social care | 2024 |
| DR8 Consulting Limited | Professional & scientific | 2026 |
| DR8 Contracting Limited | Construction | 2026 |
| DR8 Limited | Financial services | 2026 |
| Dracula Transylvanian Groceries Ltd | Wholesale & retail | 2025 |
| Dragon Bamboo Ltd | Real estate | 2025 |
| Dragonfly Family Investment Limited | Financial services | 2023 |
| Dragonsea Trading Ltd | Wholesale & retail | 2023 |
| Drain Alert Limited | Administrative & support | 1994 |
| Drainage Preston Ltd | Water & waste | 2025 |
| Dramerglen Properties Ltd | Real estate | 2024 |
| Draper Global Ltd | Financial services | 2025 |
| Drawmcgraw Ltd | Manufacturing | 2019 |
| Drayton Gardens (Flat 4) Limited | Real estate | 2023 |
| DRD Consultancy Limited | Information & communication | 2025 |
| Dream Build Projects Ltd | Construction | 2023 |
| Dream Cosmetics Ltd | Wholesale & retail | 2017 |
| Dream Slope Build Ltd | Construction | 2021 |
| Dream Stays Ltd | Real estate | 2025 |
| Dreamcatcher Designer Bridal Wear Limited | Wholesale & retail | 2003 |
| Drew Crawford Limited | Professional & scientific | 2013 |
| Drglaze Ltd | Construction | 2020 |
| Drhoop Ltd | Wholesale & retail | 2022 |
| Drifting Ducks Limited | Wholesale & retail | 2018 |
| Drip Clothing Ltd | Wholesale & retail | 2022 |
| Driplocker Limited | Wholesale & retail | 2018 |
| Drive Systems Limited | Manufacturing | 1983 |
| Drive VIP Cars Ltd | Transport & logistics | 2025 |
| Drive Wise Instructors Ltd | Education | 2024 |
| DRIVE24 Ltd | Administrative & support | 2025 |
| Driven Asset Finance Limited | Financial services | 2018 |
| Driven Vocation Ltd | Real estate | 2023 |
| Drives for Lancashire Ltd | Construction | 2025 |
| DRJ Commercial Ltd | Wholesale & retail | 2020 |
| DRJ Group Holdings Limited | Financial services | 2024 |
| DRJ Transport Ltd | Wholesale & retail | 2024 |
| Drjonesmedical Limited | Health & social care | 2014 |
| DRL Plant Hire Limited | Administrative & support | 2015 |
| Droneworks Ltd | Professional & scientific | 2014 |
| Dropbox Limited | Transport & logistics | 2019 |
| Droyale Kitchen Ltd | Hospitality | 2026 |