| City Investment & Insurance Services Limited | Financial services | 2005 |
| City Look Imports Limited | Wholesale & retail | 2001 |
| City Management Accountants Ltd | Professional & scientific | 2006 |
| City News (Preston) Limited | Wholesale & retail | 2014 |
| City of Preston Gymnastics Club Limited | Arts & recreation | 2011 |
| City of Preston Triathlon Club Ltd | Arts & recreation | 2021 |
| City Point Holdings Ltd | Construction | 2024 |
| City Property Development Ltd | Real estate | 2025 |
| City Tyres (Preston) Ltd | Other services | 2021 |
| City Walk Asset Management Limited | Households | 2025 |
| CIV Development Ltd | Real estate | 2020 |
| CIV Installation Ltd | Construction | 2026 |
| CIV Services Limited | Construction | 2016 |
| Civil Litigation Lawyer Limited | Professional & scientific | 2023 |
| Civil Slope Building Ltd | Construction | 2021 |
| Civil Support Services Ltd | Other services | 2008 |
| Civiscope Ltd | Professional & scientific | 2025 |
| Ciyani Limited | Other services | 2018 |
| Cizian Construction Ltd | Construction | 2020 |
| CJ & JM Stackhouse Ltd | Agriculture & fishing | 2014 |
| CJC Car Sales Limited | Wholesale & retail | 2006 |
| CJK Civils Limited | Construction | 2018 |
| CJM Development Services Limited | Construction | 2026 |
| CJM Maintenance Solutions Ltd | Construction | 2013 |
| CJS Accountants Ltd | Professional & scientific | 2020 |
| CJS Creative Ltd | Administrative & support | 2016 |
| CJS Trading Solutions Limited | Professional & scientific | 2025 |
| CJW Home and Garden Services Ltd | Administrative & support | 2022 |
| CK Domestic GAS Ltd | Construction | 2020 |
| Ckanoe Ltd | Professional & scientific | 2022 |
| CKD Interiors Ltd | Wholesale & retail | 2024 |
| CKG Gift Cards Limited | Hospitality | 2016 |
| CKH Media Limited | Information & communication | 2015 |
| CKR Utilities Limited | Construction | 2010 |
| CL Hvac Services Ltd. | Construction | 2014 |
| CL Projects Facilities Management Limited | Manufacturing | 2017 |
| Cladcoat Ltd | Construction | 2022 |
| Cladfast Ltd | Construction | 2020 |
| Claire Burn Limited | Professional & scientific | 2017 |
| Claires Kitchen Preston Ltd | Hospitality | 2025 |
| Clancy Care Home Ltd | Public administration | 2019 |
| Clapperton Media Associates Ltd | Professional & scientific | 2015 |
| Clare Carter Ltd | Other services | 2009 |
| Clarelle Beauty Limited | Other services | 2014 |
| Claremont Giles Limited | Professional & scientific | 2025 |
| Clarena Cosmetics UK Ltd | Wholesale & retail | 2025 |
| Clarges Rise Ltd | Extraterritorial | 2006 |
| Clarity Edinburgh Ltd | Health & social care | 2024 |
| Clarity Pure Cleaning Ltd | Administrative & support | 2025 |
| Clarity Services Ltd | Health & social care | 2024 |
| Clarity Wireless Limited | Information & communication | 2011 |
| Claritywise Limited | Professional & scientific | 2024 |
| Clarke Home Developments Ltd | Real estate | 2023 |
| Clarke Partners Limited | Administrative & support | 2025 |
| Clarkson Green Property Management Company Limited | Real estate | 2006 |
| Clarkson Holden Estate Agents Ltd | Real estate | 2021 |
| Claros Consultancy Limited | Professional & scientific | 2019 |
| Classfeel Ltd | Information & communication | 2026 |
| Classic 29 Trading AS Heatons Limited | Wholesale & retail | 2015 |
| Classic Designs (NW) Ltd | Construction | 2011 |
| Classic European Cars Limited | Wholesale & retail | 2013 |
| Classic Gardens Fylde Limited | Administrative & support | 2012 |
| Classic Kitchens Direct Ltd | Construction | 2010 |
| Classical TV Limited | Information & communication | 2007 |
| Classy Lashes Ltd | Wholesale & retail | 2026 |
| Classy Nails Bamber LT Limited | Other services | 2026 |
| Claudiajason Limited | Wholesale & retail | 2015 |
| Claughton Calf Company Limited | Agriculture & fishing | 2011 |
| Claughton Longhorns LLP | | 2022 |
| Claughton Service Centre Limited | Wholesale & retail | 2012 |
| Clawdy Transport Limited | Transport & logistics | 2019 |
| Clawz Ltd | Wholesale & retail | 2025 |
| Claybourne Recruitment Ltd | Administrative & support | 2024 |
| Claymere Consultancy Limited | Professional & scientific | 2016 |
| Clayples Limited | Other services | 2012 |
| Claystory Limited | Wholesale & retail | 2025 |
| Clayton Bakeries Limited | Professional & scientific | 2005 |
| Clayton Brook Child Care Limited | Health & social care | 2014 |
| Clayton Commercial Properties Limited | Manufacturing | 2009 |
| Clayton Farm Machinery Ltd | Wholesale & retail | 2015 |
| Clayton Green Management Company Limited | Real estate | 1989 |
| Clayton Homes (Preston) Ltd | Real estate | 2026 |
| Clayton Park Bakery Limited | Manufacturing | 2000 |
| Clayton Scaffolding Ltd | Construction | 2023 |
| Clayton Steel Ltd | Construction | 2026 |
| Clbbm Consultancy Ltd | Professional & scientific | 2020 |
| Clean & Fresh Carpets Ltd | Administrative & support | 2023 |
| Clean & Shine 4 YOU Limited | Administrative & support | 2023 |
| Clean & Shine for U Limited | Administrative & support | 2023 |
| Clean and Green Preston Limited | Water & waste | 2025 |
| Clean Care 4 U & Co Limited | Administrative & support | 2020 |
| Clean Counter Ltd | Wholesale & retail | 2026 |
| Clean for Less NW Ltd | Administrative & support | 2026 |
| Clean Living Over Wyre Ltd | Administrative & support | 2025 |
| Clean&Rise Team Limited | Administrative & support | 2020 |
| Cleanbake Coating Solutions Limited | Extraterritorial | 2013 |
| Cleaner Connect UK Ltd | Information & communication | 2025 |
| Cleaners With Pride Ltd | Administrative & support | 2020 |
| Cleaners With Pride Residential Limited | Administrative & support | 2022 |
| Cleaning Group Limited | Administrative & support | 2020 |