| Clayton Manning Investments Limited | Professional & scientific | 2020 |
| Clean & Pristine Cleaning Services Ltd | Administrative & support | 2025 |
| Clear SCI Consulting Ltd | Administrative & support | 2011 |
| Cleentek Limited | Manufacturing | 2006 |
| Clementine Arts CIC | Administrative & support | 2025 |
| Cloak Dining Ltd | Hospitality | 2019 |
| Close Horizons Limited | Financial services | 2013 |
| CLP Productions Ltd | Information & communication | 2014 |
| CMC Holdings NW Ltd | Real estate | 2019 |
| Codex Mart Ltd | Wholesale & retail | 2023 |
| Colindale Autobody Ltd | Wholesale & retail | 2014 |
| Collectric Limited | Manufacturing | 2018 |
| Communication ZAP Ltd | Information & communication | 2018 |
| Compliant Fintech Ltd | Professional & scientific | 2022 |
| Convertacar Ltd | Wholesale & retail | 2005 |
| Copperstone Ventures Ltd | Real estate | 2003 |
| Coren Ltd | Extraterritorial | 2021 |
| Crabb Bros. Builders (Maghull) Limited | Real estate | 1962 |
| Cranford Chase Ltd | Construction | 2024 |
| Createdsick LLP | | 2024 |
| Credit Monsters Limited | Administrative & support | 2008 |
| Crime-Ink Ltd | Wholesale & retail | 2022 |
| Crokers Electrical Limited | Construction | 2022 |
| Cross Consulting Solutions Ltd | Professional & scientific | 2024 |
| CSG Care Solutions Ltd | Health & social care | 2023 |
| Culture Beat Academy Ltd | Wholesale & retail | 2025 |
| Cureton GAS Services Ltd | Construction | 2011 |
| Curious Minds LAB Ltd | Information & communication | 2025 |
| CWS Audiology Ltd | Health & social care | 2025 |
| Cybernetic Ecology Ltd | Information & communication | 2025 |
| D&R MED Limited | Health & social care | 2016 |
| D20 Social Ltd | Information & communication | 2024 |
| Dani's Dine Ltd | Hospitality | 2025 |
| Danielle Louise 'the Singer in Residence' Ltd | Arts & recreation | 2025 |
| Dapats Ltd | Real estate | 2025 |
| Data-Selection Limited | Professional & scientific | 1993 |
| Date Night Creation Ltd | Arts & recreation | 2025 |
| David Chifor Trans Ltd | Manufacturing | 2025 |
| DB & E Technologies Ltd | Information & communication | 2023 |
| DCD Cars Ltd | Wholesale & retail | 2024 |
| Ddck Ltd | Other services | 2023 |
| Deadeye Comics Ltd | Information & communication | 2025 |
| Delavor Properties Limited | Households | 2008 |
| Delivering Manageable Construction Solutions Limited | Construction | 2025 |
| Deva Senior Care Services Ltd | Health & social care | 2007 |
| Devonshire Construction Ltd | Construction | 2022 |
| Devonshire Medical Consulting Limited | Health & social care | 2016 |
| DH Lean Solutions Limited | Professional & scientific | 2008 |
| Diamond Computer Contractors Limited | Real estate | 1998 |
| Digital Creativity in Disability Limited | Information & communication | 2012 |
| Digital Disguise Limited | Professional & scientific | 2012 |
| Doolan Associates Ltd | Construction | 2017 |
| Dowmed Limited | Health & social care | 2023 |
| DP Estates NW Limited | Real estate | 2025 |
| DR Fairoz Fayaz Ltd | Health & social care | 2016 |
| Dreams Care Ltd | Administrative & support | 2018 |
| Dressed by RJ Limited | Manufacturing | 2021 |
| Drey Barbing Saloon Ltd | Other services | 2025 |
| Dromore Safety Services Ltd | Professional & scientific | 2012 |
| Dublin Limited | Professional & scientific | 2021 |
| Dunard Walk Management Company Limited | Households | 2017 |
| Durley Garage Limited | Wholesale & retail | 2002 |
| DVW Services Limited | Administrative & support | 2016 |
| Eastcourt Ltd | Administrative & support | 2017 |
| Easy Life Care Limited | Administrative & support | 2003 |
| Easy Pick Convenience Limited | Wholesale & retail | 2025 |
| Eatzr Limited | Wholesale & retail | 2024 |
| Eco Green Cleaners UK Ltd | Manufacturing | 2014 |
| Ecovolt Electric Ltd | Construction | 2025 |
| Edwards News Limited | Wholesale & retail | 2007 |
| Eitop Ltd | Administrative & support | 2015 |
| EJ Properties & Holdings Limited | Real estate | 2025 |
| EJL Joinery Solutions Ltd | Construction | 2022 |
| Eleanor Lodge MC Ltd | Administrative & support | 2017 |
| Eleanor Park Management Company Limited | Other services | 2001 |
| ELF Block Management Ltd | Households | 2025 |
| Elite Rentals Wirral Limited | Real estate | 2018 |
| Elite-Sn Ltd | Arts & recreation | 2019 |
| Elle Creations Limited | Information & communication | 2023 |
| ELM Site Management Ltd | Construction | 2012 |
| Ematt Limited | Households | 2025 |
| Emma's Ices Ltd | Hospitality | 2018 |
| Empire Electrical & Alarms Limited | Construction | 2014 |
| Empire Luxury Developments Limited | Construction | 2021 |
| Engineering Quality Ltd | Professional & scientific | 2025 |
| Enhance Property Repair and Maintenance Ltd | Construction | 2019 |
| Enterprise Property Management Limited | Real estate | 2019 |
| Enterprise Worldwide Ltd | Information & communication | 2012 |
| Entire AI Limited | Professional & scientific | 2020 |
| Envirolyte Disinfection & Liquid Systems UK Ltd | Manufacturing | 2020 |
| Envirolyte ECA UK Ltd | Manufacturing | 2014 |
| Eras Platform Ltd | Information & communication | 2026 |
| Ericthecat Ltd | Financial services | 2018 |
| Ethnico Coffee Ltd | Wholesale & retail | 2024 |
| EVM Rocks Ltd | Arts & recreation | 2019 |
| Evolve Architects Limited | Professional & scientific | 2015 |
| Evolve Design & Develop Ltd | Construction | 2021 |
| Excellence in Measurement Technology Limited | Professional & scientific | 2010 |
| Extropic Change Limited | Construction | 2016 |
| Faeried Soul Ltd | Other services | 2020 |