| ROB Ineson Creative Ltd | Information & communication | 2023 |
| Robert Adam Estate Agents Limited | Real estate | 2024 |
| Robert Bowen Limited | Professional & scientific | 2017 |
| Robert Brain Ltd | Information & communication | 2018 |
| Robert Knight Limited | Professional & scientific | 2011 |
| Roberts Performance Ltd | Wholesale & retail | 2022 |
| Robmccarthytv Limited | Information & communication | 2024 |
| Robson Bale Limited | Administrative & support | 2013 |
| Rock Internet Limited | Information & communication | 2008 |
| Rockandgrowth Limited | Information & communication | 2018 |
| Rockmas Limited | Professional & scientific | 2022 |
| ROI Soleil Ltd | Administrative & support | 2017 |
| Rolmak Ltd | Information & communication | 2025 |
| Romz-Fitness Limited | Arts & recreation | 2024 |
| Roofs by LEE Renouf Ltd | Construction | 2023 |
| Rooskagh East Limited | Real estate | 2024 |
| Roretti Limited | Professional & scientific | 2019 |
| Rose Gold Academy Ltd | Education | 2025 |
| Rose Property Limited | Real estate | 2016 |
| Rose Villa Ltd | Households | 2024 |
| Roseark Limited | Real estate | 2005 |
| Rosebank Management Limited | Professional & scientific | 2002 |
| Rosebuild Properties Limited | Real estate | 2000 |
| Rosedale Independent Social Work Services Limited | Health & social care | 2014 |
| Rosegem Limited | Administrative & support | 2014 |
| Rosenburg Financial Limited | Other services | 2021 |
| Rosenburg Group Limited | Professional & scientific | 2021 |
| Rosina Court Management Company Limited | Households | 2016 |
| Roskerry Building Services Ltd | Professional & scientific | 2013 |
| Rost International Trading Limited | Wholesale & retail | 2014 |
| Roti Spot Limited | Hospitality | 2024 |
| ROW 789 Limited | Construction | 2015 |
| Rowan Cable Products Limited | Extraterritorial | 2013 |
| Rowan Edward Group Ltd | Financial services | 2026 |
| Rowan Edward Land Ltd | Real estate | 2024 |
| Royce Power Transmissions Limited | Wholesale & retail | 1984 |
| Royce Sales Limited | Other services | 2016 |
| Royce Technology (UK) Ltd | Extraterritorial | 2018 |
| Roynon Alexander Ltd | Construction | 2018 |
| ROZ 2017 Ltd | Other services | 2025 |
| RP Asset Integrity Ltd | Construction | 2026 |
| RQ Advisory Limited | Professional & scientific | 2021 |
| RS Beauty Bar Ltd | Other services | 2020 |
| RS Tax Consultancy Limited | Professional & scientific | 2024 |
| Rsja Care Limited | Health & social care | 2021 |
| RSL Contracts Limited | Professional & scientific | 2018 |
| RT Innovations Ltd | Professional & scientific | 2009 |
| Ruby Personal Services Ltd | Other services | 2018 |
| Rudgwick Limited | Professional & scientific | 1993 |
| Rudi Transport Limited | Transport & logistics | 2018 |
| Rumours (London) Ltd | Hospitality | 2019 |
| Rushey Estates Limited | Administrative & support | 2024 |
| Rushmore Ltd | Administrative & support | 2021 |
| RWS Trading Limited | Administrative & support | 2016 |
| Ryan Fielder Ltd | Professional & scientific | 2022 |
| S Cook Film Services Ltd | Information & communication | 2022 |
| S G Developments UK Limited | Construction | 2004 |
| S J Eastern Fireproofing Ltd | Construction | 2019 |
| S Kota & Sons Limited | Health & social care | 2022 |
| S R Creations Ltd | Administrative & support | 2022 |
| S. B. Building Consultants Limited | Professional & scientific | 1997 |
| S. E. Beauty Ltd | Other services | 2017 |
| S. J. Eastern Developments Limited | Construction | 2005 |
| S.J. Eastern Carpentry & Joinery Limited | Construction | 2001 |
| S.P Williams Consulting Ltd | Professional & scientific | 2012 |
| S278 London Limited | Construction | 2025 |
| SA Auto Wash Ltd | Wholesale & retail | 2024 |
| SA Property Management Services Ltd | Households | 2025 |
| Sablevert Limited | Manufacturing | 2026 |
| SABO1972 Ltd | Hospitality | 2022 |
| Safe and Smart Limited | Wholesale & retail | 2025 |
| Safe Developments PB Limited | Real estate | 2022 |
| Safe Haven Psychiatry UK Ltd | Health & social care | 2024 |
| Safe Properties PB Limited | Financial services | 2019 |
| Safe Recruit Holdings Limited | Financial services | 2026 |
| Safecap (UK) Services Ltd | Administrative & support | 2025 |
| Safelake Projects LLP | | 2025 |
| Safety and Health Knowhow Ltd | Professional & scientific | 2015 |
| Saffron Skies Ltd | Professional & scientific | 2019 |
| Safinity Ltd | Professional & scientific | 2021 |
| SAI Sathvik Technologies Limited | Information & communication | 2014 |
| Saint Cubes Ltd | Professional & scientific | 2019 |
| Saint Fanourios Limited | Real estate | 2014 |
| Sala LU Enterprise Ltd | Health & social care | 2022 |
| Sala LU Global Ltd | Health & social care | 2026 |
| Saleem Technologies Ltd | Information & communication | 2015 |
| Salon DES Refuses Limited | Administrative & support | 2025 |
| Salon DES Refuses London Limited | Administrative & support | 2025 |
| Salon Fitters Ltd | Professional & scientific | 2025 |
| Salon Support UK Limited | Other services | 2001 |
| Salute BIO Masters Ltd | Administrative & support | 2012 |
| Samantha Foley Ltd | Information & communication | 2026 |
| Samaritan IT Service Ltd | Other services | 2023 |
| Samisons (UK) Limited | Wholesale & retail | 2003 |
| Sammy Pitta Limited | Manufacturing | 2026 |
| SAN Anglo Logistics Limited | Transport & logistics | 2019 |
| SAN Marino Investments Limited | Administrative & support | 2008 |
| San.Boa Ltd | Administrative & support | 2015 |
| Sandpoint Ltd | Real estate | 2023 |
| Sandra Estates Limited | Real estate | 1944 |