| Dasa Estates Limited | Real estate | 2022 |
| Dasino Construction Limited | Construction | 2003 |
| Dasino Limited | Real estate | 1999 |
| Data Consulting Associates Ltd | Information & communication | 2019 |
| Data Swift (South East) Limited | Transport & logistics | 1987 |
| Datablack International Limited | Information & communication | 1998 |
| Databods Limited | Professional & scientific | 2015 |
| Datagraf Ltd | Information & communication | 2008 |
| Dataswift 2000 Limited | Extraterritorial | 1996 |
| Datrus Ltd | Education | 2013 |
| Datum CCM London Limited | Construction | 2021 |
| Datum Contracts and Construction Management Limited | Construction | 2012 |
| Datum Creative Media Limited | Manufacturing | 2018 |
| Davati Compliance & Risk Advisory Limited | Professional & scientific | 2024 |
| Dave Bennett Commercials Ltd | Wholesale & retail | 2025 |
| Dave Bennett Holdings Ltd | Financial services | 2025 |
| Dave Bennett Limited | Water & waste | 2016 |
| Dave Edwards BIZ Limited | Information & communication | 2009 |
| David Burrows Electrical Limited | Wholesale & retail | 1974 |
| David Ellis Limited | Professional & scientific | 2003 |
| David Freight Services Ltd | Transport & logistics | 2025 |
| Davidshan Properties Ltd | Real estate | 2018 |
| Daviola Trading Limited | Wholesale & retail | 2025 |
| Davis Music Ltd | Information & communication | 2026 |
| Davnear Limited | Households | 1980 |
| Davran Limited | Information & communication | 2008 |
| Dayk Properties Ltd | Real estate | 2026 |
| DBM Events Limited | Arts & recreation | 2025 |
| DBO Holdings Limited | Information & communication | 2014 |
| DC Accountancy Services Limited | Financial services | 2018 |
| DC Music Services Limited | Arts & recreation | 2014 |
| DCT Property Ltd | Real estate | 2017 |
| DD Faculties Ltd | Arts & recreation | 2025 |
| Deal Kings Ltd | Extraterritorial | 2016 |
| Debwin Holdings | Financial services | 2021 |
| Deca Motors Limited | Administrative & support | 2018 |
| Decor N More Limited | Professional & scientific | 2014 |
| Decort Ltd | Construction | 2026 |
| DEE Stanford Aromatics Limited | Wholesale & retail | 2025 |
| DEE Stanford Limited | Other services | 2025 |
| Deeadivine Ltd | Other services | 2022 |
| Deeper Insights Ltd | Professional & scientific | 1991 |
| Deepnet Security Limited | Information & communication | 2003 |
| Deercin Design Ltd | Construction | 2006 |
| Deewee Limited | Arts & recreation | 2015 |
| Defined Builds Limited | Construction | 2017 |
| Defining Care Limited | Health & social care | 2025 |
| Defining Futures Limited | Health & social care | 2022 |
| Defining Mynds Limited | Education | 2026 |
| DEH Personal Shopper Ltd | Wholesale & retail | 2025 |
| Dehexagon Ltd | Information & communication | 2021 |
| Dekka Limited | Information & communication | 2022 |
| Delieu Electrical Services Ltd | Construction | 2017 |
| Delieu Properties Limited | Real estate | 2021 |
| Delta 'T' (Trace Heating) Limited | Construction | 1978 |
| Delta T Holdings Limited | Financial services | 2016 |
| Delta T Trading LLP | | 2012 |
| DEM4 Ltd | Wholesale & retail | 2025 |
| Denbourne Investments Limited | Real estate | 1980 |
| Dennis Mabry Design Limited | Information & communication | 2005 |
| Denny Affordable Homes Limited | Hospitality | 2025 |
| Denny Global Professions Education College Limited | Education | 2023 |
| Denny Independent Intensive Worldwide Investigations Bureau Limited | Administrative & support | 2025 |
| Denny Meds Pharms Limited | Professional & scientific | 2025 |
| Denny Scientific Research Inventions & Innovations Development Centre Limited | Professional & scientific | 2025 |
| Denny Studios Production/ Multimedia Training Limited | Information & communication | 2025 |
| Denny Worldwide General Transports Limited | Wholesale & retail | 2025 |
| Densheds Limited | Wholesale & retail | 2003 |
| Dental Support Solutions Ltd | Professional & scientific | 2023 |
| Department of Athletes Ltd | Wholesale & retail | 2026 |
| Derg Construction Ltd | Construction | 2024 |
| Derin Driving School Ltd | Education | 2024 |
| Dermology Academy Ltd | Other services | 2024 |
| Derwick Limited | Other services | 1972 |
| Desborough Care Limited | Health & social care | 2021 |
| Desi Grocers UK Limited | Wholesale & retail | 2025 |
| Design Buro Production Ltd | Professional & scientific | 2015 |
| Design Factors Limited | Professional & scientific | 2002 |
| Design for Leisure Ltd | Manufacturing | 2005 |
| Design Rationale Limited | Manufacturing | 1992 |
| Design Space Studio Limited | Professional & scientific | 2008 |
| Design Studio Manufacturing UK Limited | Wholesale & retail | 2016 |
| Designer Mobiles Ltd | Wholesale & retail | 2010 |
| Designs @ A.J.C Limited | Other services | 2016 |
| Despacio Limited | Arts & recreation | 2013 |
| Deste Ltd | Hospitality | 2024 |
| Destination Beauty Ltd | Wholesale & retail | 2019 |
| Destiny Goal Ltd | Transport & logistics | 2021 |
| Detox the Noise Ltd | Information & communication | 2024 |
| Deuxclan Limited | Information & communication | 2006 |
| Deval Investments Ltd | Real estate | 2024 |
| Devblocks Tech Ltd | Information & communication | 2026 |
| Devi Mart Ltd | Wholesale & retail | 2026 |
| Dewitt Dental Ltd | Health & social care | 2017 |
| Dexis Development Ltd | Information & communication | 2022 |
| DF Financial Services Limited | Financial services | 2004 |
| DFD Consultants Ltd | Professional & scientific | 2018 |
| DGN Cars Ltd | Wholesale & retail | 2015 |
| DGR (Direct Global Resources) Limited | Other services | 2024 |
| Dharma Poshanam Services Ltd | Information & communication | 2026 |