| Daydreamsrv Ltd | Professional & scientific | 2007 |
| Daymade Ltd | Administrative & support | 2019 |
| Days Window & Door Services Limited | Construction | 2001 |
| Dazzle Business Support Limited | Professional & scientific | 2022 |
| DB Shareholdings Limited | Financial services | 2025 |
| Dbmk Limited | Manufacturing | 2025 |
| DBV Electrical Installment Limited | Professional & scientific | 2017 |
| DC Electrical Contractors (Southern Counties) Limited | Manufacturing | 2021 |
| DC Electrical Contractors (Southern) Limited | Manufacturing | 2016 |
| DC Electrical Services & Property Maintenance Ltd | Water & waste | 2019 |
| DC Energy Solutions Limited | Manufacturing | 2023 |
| DC Properties (Southern) Ltd | Real estate | 2025 |
| DC Property Core Ltd | Real estate | 2026 |
| DC Vehicle Leasing Ltd | Administrative & support | 2022 |
| DCI Property LLP | | 2005 |
| DCI Refrigeration & Electrical 2018 Limited | Manufacturing | 2018 |
| DCI Refrigeration & Electrical Limited | Manufacturing | 2000 |
| DCJ Electrical Ltd | Construction | 2025 |
| DCW Contract Services Ltd | Construction | 2026 |
| DDF Accountancy Ltd | Professional & scientific | 2024 |
| DDG Building Services Ltd | Construction | 2020 |
| DE Vere Properties Limited | Construction | 2010 |
| DE Launay London Limited | Households | 2020 |
| Deacon Design Ltd | Professional & scientific | 2016 |
| Deacon Group Investments Limited | Financial services | 2017 |
| Deal Direct Financial Solutions Limited | Financial services | 2005 |
| Dealmaker Systems 2018 Limited | Information & communication | 2018 |
| DEALSCORNER555 Ltd | Wholesale & retail | 2026 |
| Deanhale Limited | Health & social care | 2015 |
| Dearbois Limited | Hospitality | 2014 |
| Debbie Timberlake Training Limited | Arts & recreation | 2006 |
| Debdarks Ltd | Health & social care | 2025 |
| Debunked Limited | Manufacturing | 2019 |
| Decadent Living Ltd | Real estate | 2018 |
| Deco WHU Ltd | Construction | 2016 |
| Decore Home Designs Ltd | Wholesale & retail | 2018 |
| DEE Dee's Deliveries Ltd | Hospitality | 2023 |
| DEE Living Ltd | Real estate | 2019 |
| Dee-Genesis Limited | Health & social care | 2019 |
| Deepforge Capital Ltd | Financial services | 2026 |
| Defeated Skateboards Ltd | Wholesale & retail | 2021 |
| Deflinks Ltd | Professional & scientific | 2013 |
| Defserv Limited | Professional & scientific | 2023 |
| Dejo Squared Invest Ltd | Financial services | 2014 |
| Delegate MEE Limited | Information & communication | 2024 |
| Delight Health Care Services Limited | Health & social care | 2023 |
| Delightful Rooms Limited | Real estate | 2017 |
| Delphis Solutions Ltd | Professional & scientific | 2015 |
| Delta Holdings Southern Limited | Financial services | 2010 |
| Delta Ventilation Limited | Manufacturing | 1995 |
| Delta Ventilation Service Ltd | Manufacturing | 2019 |
| Deluxe Dwellings Limited | Real estate | 2020 |
| Delwyr Holdings Limited | Financial services | 2024 |
| DEM Elect Ltd | Professional & scientific | 2016 |
| DEN 59 Ltd | Real estate | 2016 |
| Denes Right Choice Window Cleaning Ltd | Administrative & support | 2015 |
| Denhiks Enterprise Ltd | Professional & scientific | 2025 |
| Denis Mini Market Ltd | Wholesale & retail | 2026 |
| Denisa Accounting Services Ltd | Professional & scientific | 2026 |
| Denmead Property Services Limited | Construction | 2014 |
| Denney Decor Ltd | Construction | 2025 |
| Dental Hygiene Care Ltd | Health & social care | 2022 |
| Dental Therapy & Aesthetics Ltd | Health & social care | 2024 |
| Denvilles Consultants Ltd | Hospitality | 2024 |
| Deoforti IT Limited | Information & communication | 2025 |
| Deoforti Limited | Professional & scientific | 2025 |
| Deployable Solutions Limited | Administrative & support | 2021 |
| Derby Motors Copnor Ltd | Wholesale & retail | 2015 |
| Derek Smith Dairies Limited | Wholesale & retail | 2009 |
| Derwent Residential Care Limited | Health & social care | 2002 |
| DES Haulage Limited | Transport & logistics | 2007 |
| Design & Build ( Southern) Ltd | Construction | 2019 |
| Design 1805 Ltd | Manufacturing | 2019 |
| Design by Dugan Ltd | Professional & scientific | 2026 |
| Design Renew Systems Limited | Construction | 2023 |
| DESK2EDUCATE Ltd | Information & communication | 2024 |
| Deskpilot HQ Ltd | Information & communication | 2025 |
| Dessert Island Ltd | Hospitality | 2025 |
| Destination Board Games Ltd | Manufacturing | 2024 |
| Destination Burgers Limited | Hospitality | 2026 |
| Destiny Healthcare (PVT) Ltd | Health & social care | 2016 |
| Detailphase Limited | Professional & scientific | 1998 |
| Detection Fire & Security Ltd | Construction | 2021 |
| Development NOW Ltd | Construction | 2025 |
| Devereaux Investments Limited | Professional & scientific | 2010 |
| Devi Serene Studio Ltd | Information & communication | 2024 |
| Dewaz Bookkeeping Ltd | Professional & scientific | 2019 |
| DEX Construction Limited | Construction | 2014 |
| DEX Homes (Portchester) Limited | Construction | 2014 |
| DEX Homes (Portsmouth) Limited | Construction | 2020 |
| DEX Homes Limited | Financial services | 2014 |
| DF Carpet Cleaning Limited | Other services | 2011 |
| DFX Trading Ltd | Financial services | 2022 |
| DG Rating Limited | Professional & scientific | 2023 |
| DG Roofing & Cladding Ltd | Construction | 2024 |
| DG Roofing (Southern) Ltd | Construction | 2022 |
| DG Windows Doors and Conservatories Limited | Construction | 2020 |
| Dg-Infosec-Consulting Limited | Administrative & support | 2016 |
| DGB Tyre Imports Limited | Wholesale & retail | 2014 |
| Dgbb Arnold Holdings Limited | Financial services | 2024 |