| Econautique Ltd | Financial services | 2024 |
| Ecosafe Heating Limited | Construction | 2013 |
| Ecosite Ltd | Information & communication | 2023 |
| Ecosphere Ecology Ltd | Professional & scientific | 2025 |
| Ecosse Engineering Ltd | Manufacturing | 2022 |
| Ecreation Media Technology Limited | Information & communication | 2012 |
| ECS Property Managers Ltd | Real estate | 2022 |
| Ecuworx Ltd | Wholesale & retail | 2018 |
| Eczclaim Ltd | Wholesale & retail | 2025 |
| Edansa Innovations Ltd | Professional & scientific | 2024 |
| EDC Rail Project Consulting Limited | Professional & scientific | 2022 |
| EDC Warehouse Ltd | Wholesale & retail | 2023 |
| Eddieson Group Ltd | Construction | 2020 |
| Edementum Limited | Financial services | 2024 |
| Eden & Co Ltd | Professional & scientific | 2012 |
| Eden Company Secretaries Ltd | Extraterritorial | 2013 |
| Eden Electrical Installations Ltd | Construction | 2017 |
| Eden Stone Designs Ltd | Wholesale & retail | 2023 |
| Eden Support Housing Ltd | Real estate | 2026 |
| Eden Support Housing Services CIC | Real estate | 2026 |
| Edenhurst (Management) Limited | Households | 1960 |
| Edephant Ltd | Information & communication | 2020 |
| EDG Interiors Ltd | Construction | 2016 |
| Edge Umbrella Limited | Administrative & support | 2020 |
| Edhit (Smc-Private) Limited | Wholesale & retail | 2021 |
| Edith Healthcare Limited | Health & social care | 2017 |
| EDM Carpenters Ltd | Manufacturing | 2012 |
| EDN Management Services Limited | Other services | 2024 |
| Edonistart Ltd | Professional & scientific | 2013 |
| EDS Building Connections Ltd | Professional & scientific | 2024 |
| EDS Orthodontics Limited | Manufacturing | 2018 |
| Edsn Ltd | Professional & scientific | 2023 |
| Educad Ltd | Professional & scientific | 2022 |
| Edward Chappell Financial Services Limited | Financial services | 2006 |
| Edward Fitzsimmons & Associates Limited | Other services | 2014 |
| Edward Meeks User Experience Design Ltd | Professional & scientific | 2022 |
| Edward Naylor Limited | Real estate | 2022 |
| Edward T Contractors Ltd | Construction | 2022 |
| Edwards Covell Associates CIC | Professional & scientific | 2013 |
| Edwards Facility Services Ltd | Real estate | 2022 |
| Edwards Inspire Ltd | Other services | 2017 |
| Edwards Support Services Limited | Real estate | 2012 |
| EDY Cars Limited | Wholesale & retail | 2025 |
| Eebs CIS Limited | Administrative & support | 2017 |
| Eesys Tech Limited | Professional & scientific | 2024 |
| Eezi Clean Ltd | Administrative & support | 2012 |
| Efcuk Ltd | Arts & recreation | 2026 |
| Effective Coaching LLP | | 2020 |
| Effective Training and Development Limited | Education | 1991 |
| Effemey Cosby Advertising Limited | Professional & scientific | 2001 |
| Efixstore Ltd | Wholesale & retail | 2024 |
| Efurbished Technologies Limited | Wholesale & retail | 2026 |
| Egdon Developments Limited | Agriculture & fishing | 2004 |
| Egeberg Group Ltd | Construction | 2023 |
| Egemen Eren Ltd | Education | 2022 |
| Egerton Investments Altrincham Limited | Real estate | 2012 |
| Egerton Investments Limited | Real estate | 1997 |
| Egerton Securities Cheadle Limited | Real estate | 2014 |
| Egerton Securities Limited | Real estate | 2011 |
| Egerton Strathblane Limited | Professional & scientific | 2015 |
| Eggerding Properties Limited | Real estate | 1996 |
| Eglc Enterprises Limited | Real estate | 2017 |
| Egret Capital Limited | Education | 2015 |
| Egret Finance Ltd | Financial services | 2010 |
| Egret Press Ltd | Information & communication | 2014 |
| Ehfp Ltd | Construction | 2021 |
| Ehst Holdings Ltd | Financial services | 2019 |
| Ehst Limited | Real estate | 2019 |
| Eight Bankside Ltd | Construction | 2020 |
| Eightfold Solutions Ltd | Information & communication | 2024 |
| Eilidh Mcintyre Ltd | Arts & recreation | 2021 |
| EJ Group Properties Ltd | Real estate | 2025 |
| EJ Howe Ltd | Wholesale & retail | 2026 |
| Ejbparts Ltd | Wholesale & retail | 2023 |
| EJG Properties Limited | Real estate | 2023 |
| Ekaccessories Ltd | Wholesale & retail | 2018 |
| EKM Investments LLP | | 2018 |
| EL & RL (2) Ltd | Real estate | 2021 |
| EL Gran Capitan Limited | Professional & scientific | 2022 |
| EL Skin & Aesthetics Ltd | Health & social care | 2022 |
| El-Heis Dermatology Limited | Health & social care | 2025 |
| El-Mono Limited | Arts & recreation | 2013 |
| Elaar Ltd | Financial services | 2026 |
| Elanajay.Consulting Limited | Professional & scientific | 2018 |
| Elavate Technology Limited | Manufacturing | 2026 |
| Electradersinc Ltd | Wholesale & retail | 2024 |
| Electranet Solutions Ltd | Manufacturing | 2011 |
| Electric DB Limited | Information & communication | 2021 |
| Electric Drive Vehicles Limited | Extraterritorial | 2007 |
| Electric Heating Solutions (UK) Ltd | Wholesale & retail | 2004 |
| Electric Locking Systems Limited | Wholesale & retail | 2000 |
| Electric-Powered Innovation Ltd | Professional & scientific | 2024 |
| Electrical 1337 Limited | Construction | 2025 |
| Electro Mechanical Systems (Holdings) Limited | Financial services | 2024 |
| Electro Mechanical Systems Limited | Wholesale & retail | 1985 |
| Electronic Receptionist Ltd | Information & communication | 2025 |
| Electronical Wiring Limited | Administrative & support | 2016 |
| Electrostatic Workshop Limited | Administrative & support | 2023 |
| Elegance Barbers (Poole) Ltd | Other services | 2019 |
| Elegance Within Design Ltd | Professional & scientific | 2025 |