| Strategic Script Solutions Ltd | Professional & scientific | 2025 |
| Strategic Solutions Platform Services Limited | Extraterritorial | 2021 |
| Strategie Reklamy Ltd | Administrative & support | 2017 |
| Strategy Time Limited | Information & communication | 2018 |
| Strategynet Ltd | Professional & scientific | 2021 |
| Stratevise Ltd | Professional & scientific | 2026 |
| Stratfield Commercial LLP | | 2013 |
| Stratfield Lodge Ltd | Health & social care | 2003 |
| Stratford Place Publishing Company Limited | Information & communication | 2022 |
| Stratford Roofing Limited | Construction | 1998 |
| Stratifyworks Ltd | Information & communication | 2025 |
| Stratton Digital Advisory Services Limited | Information & communication | 2026 |
| Stratus Security Ltd | Administrative & support | 2019 |
| Strawberry Hill Homes Limited | Professional & scientific | 2020 |
| Strazsky & Co Ltd | Hospitality | 2026 |
| Stream House Group Limited | Financial services | 2025 |
| Streamgznfr Limited | Wholesale & retail | 2025 |
| Streetscope Technologies Limited | Public administration | 2022 |
| Strength Within Limited | Wholesale & retail | 2025 |
| Stretch Play Hire Limited | Hospitality | 2018 |
| Stripes Poole Ltd | Professional & scientific | 2019 |
| Strive Dorset Ltd | Health & social care | 2023 |
| Stroke Prevention Ltd | Information & communication | 2025 |
| Stromhaven Ltd | Financial services | 2025 |
| Strong Search Ltd | Administrative & support | 2025 |
| Strongbrick Ltd | Real estate | 2026 |
| Stronglytics Ltd | Administrative & support | 2018 |
| Strove Technologies Ltd | Other services | 2022 |
| Struwig Consulting Limited | Information & communication | 2008 |
| Stryzone Ltd | Wholesale & retail | 2025 |
| STS Brickwork Limited | Construction | 2018 |
| STT Digital Products Ltd | Information & communication | 2025 |
| Stuart Kirby Consultancy Ltd | Professional & scientific | 2025 |
| Studio 6 Media Limited | Information & communication | 2021 |
| Studio BR Limited | Wholesale & retail | 2025 |
| Studio Cullen Limited | Professional & scientific | 2024 |
| Studio Deards Ltd | Construction | 2025 |
| Studio Hagger Ltd | Professional & scientific | 2013 |
| Studio Isekai Ltd | Information & communication | 2022 |
| Studio Kudos Ltd | Other services | 2008 |
| Studio Maiva Ltd | Professional & scientific | 2024 |
| Studio Make Group Limited | Real estate | 2004 |
| Studio Mara Interiors Ltd | Professional & scientific | 2023 |
| Studio Moda Ltd | Professional & scientific | 2015 |
| Studio Partnr Ltd | Information & communication | 2025 |
| Studio Series Ltd | Other services | 2024 |
| Studio Unbound Ltd | Administrative & support | 2020 |
| Studioofnew Ltd | Professional & scientific | 2025 |
| Studland Court Bournemouth (Freehold) Limited | Households | 2004 |
| Studywell Publications Ltd | Wholesale & retail | 2010 |
| Stupid Puppy Ltd | Information & communication | 2024 |
| Sturminster TZZ Estates LLP | | 2014 |
| STX Negocios Ltd | Information & communication | 2025 |
| Style and Surface Limited | Professional & scientific | 2025 |
| Styled by Bree Edafe Ltd | Other services | 2022 |
| SU Real Estate Investment Ltd | Real estate | 2025 |
| Sub-U-Like Limited | Real estate | 2014 |
| SUB3RACING Ltd | Administrative & support | 2024 |
| Subayr Ltd | Financial services | 2019 |
| Subcontractme Online Ltd | Administrative & support | 2020 |
| Subject Marsec Expert Ltd | Professional & scientific | 2014 |
| Sublime-Professional Ltd | Construction | 2025 |
| Subsea Scope Limited | Professional & scientific | 2025 |
| Subtle Styling Ltd | Other services | 2024 |
| Subu Trading Ltd | Hospitality | 2000 |
| Success Mindset Solutions Ltd | Information & communication | 2019 |
| Such Salinger Peters Ltd | Professional & scientific | 1984 |
| Sudatech Networks Limited | Information & communication | 2025 |
| SUE Stone Limited | Administrative & support | 2006 |
| Sufyan Goods Ltd | Wholesale & retail | 2024 |
| Sugar and Slice Ltd | Manufacturing | 2026 |
| Suite and BED Shop Limited | Wholesale & retail | 2021 |
| Suji Limited | Health & social care | 2023 |
| Sukoshi Ltd | Information & communication | 2021 |
| Suledate Ltd | Real estate | 2019 |
| Sultan Alshukaili Limited | Wholesale & retail | 2026 |
| Sumerian Games Ltd | Manufacturing | 2024 |
| Summar Ltd | Wholesale & retail | 2023 |
| Summation Quartic Limited | Financial services | 2025 |
| Summer Trading Poole Limited | Hospitality | 2018 |
| Summerfields Technology Limited | Information & communication | 2022 |
| Summerlands Care Limited | Health & social care | 2009 |
| Summit 5F Holdings Limited | Real estate | 2025 |
| Summit Air Conditioning Limited | Energy | 2024 |
| Summit Brands Digital Ltd | Wholesale & retail | 2026 |
| Summit Fabrication and Welding Ltd | Manufacturing | 2020 |
| Summit Mechanical Services Limited | Construction | 2018 |
| Summit Windows & Shop Fronts Ltd | Construction | 2024 |
| Sumo Flowers Limited | Wholesale & retail | 2010 |
| Sun and Sea Ltd | Real estate | 2020 |
| Sun Valley Developments Limited | Construction | 1995 |
| Sun Valley Properties Limited | Real estate | 2000 |
| Sunbeam Cycle Co Limited | Manufacturing | 2026 |
| Sunday Rodeo the Label Limited | Wholesale & retail | 2026 |
| Sundene House Management Limited | Households | 2004 |
| Sundew Property Ltd | Real estate | 2021 |
| Sunflower Wong Limited | Other services | 2018 |
| Sunglasses for Sport Ltd | Wholesale & retail | 2007 |
| Sunline Electrics Ltd | Construction | 2025 |
| Sunningdale Gardens Management Company Limited | Households | 1995 |