| SLN Haulage Ltd | Transport & logistics | 2021 |
| SLN Transport Dorset Limited | Transport & logistics | 2026 |
| Sloop Yachting Services Limited | Other services | 2022 |
| Slow Decay Limited | Arts & recreation | 2010 |
| Slps Energy Ltd | Other services | 2012 |
| SM Business Management Services Ltd | Professional & scientific | 2025 |
| SM Electrical (UK) Limited | Construction | 2013 |
| SM Holdings Dorset Ltd | Real estate | 2025 |
| SM Virtual Ltd | Administrative & support | 2023 |
| Sm-Cars Bournemouth Ltd | Wholesale & retail | 2024 |
| Smart Active Monitoring Limited | Information & communication | 2013 |
| Smart Automobiles Limited | Wholesale & retail | 2018 |
| Smart Buy Community Ltd | Wholesale & retail | 2025 |
| Smart Digital Factory Limited | Information & communication | 2016 |
| Smart Factory Direct (UK) Ltd | Wholesale & retail | 2021 |
| Smart Global Industries Ltd | Manufacturing | 2017 |
| Smart Home Supplies Ltd | Administrative & support | 2005 |
| Smart Phones Repair Ltd | Other services | 2019 |
| Smart Rewards Ltd | Information & communication | 2023 |
| Smart Volution Limited | Administrative & support | 2005 |
| Smarter Business Tech Ltd | Information & communication | 2025 |
| Smartgrade Ltd | Information & communication | 2020 |
| Smartify Tech Ltd | Information & communication | 2025 |
| Smbeauty Ltd | Other services | 2019 |
| SMC Soluções Digitais Limited | Information & communication | 2025 |
| SMD Stockyards Limited | Wholesale & retail | 2012 |
| SME Controls Limited | Professional & scientific | 2021 |
| SMG Industries Ltd | Other services | 2011 |
| Smht Properties Ltd | Real estate | 2021 |
| Smic Marketing Ltd | Professional & scientific | 2024 |
| Smiggot Limited | Wholesale & retail | 2024 |
| Smigla Transport Limited | Transport & logistics | 2017 |
| Smile 82 Ltd | Professional & scientific | 2024 |
| Smile and Experience TLC CIC | Health & social care | 2018 |
| Smile Best Ltd | Information & communication | 2023 |
| Smile Correct Limited | Health & social care | 2020 |
| Smile for Humanity Ltd | Health & social care | 2025 |
| Smile Mobile Chef Limited | Hospitality | 2020 |
| Smile Spa Care Ltd | Wholesale & retail | 2026 |
| Smiles Consulting Ltd | Information & communication | 2023 |
| Smiles Properties Ltd | Real estate | 2017 |
| Smirley Care Services Limited | Administrative & support | 2025 |
| Smith Ireland Lawn Specialists Limited | Administrative & support | 2025 |
| Smith Ladino Limited | Professional & scientific | 2017 |
| Smith Moorhouse Property Management Limited | Real estate | 2019 |
| Smithfield House Children's Nursery Limited | Education | 2010 |
| Smiths Signature Flooring Ltd | Construction | 2025 |
| Smitten Properties Limited | Real estate | 2022 |
| Smockies Ltd | Wholesale & retail | 2021 |
| Smoke Vent Direct Limited | Extraterritorial | 2012 |
| Smokeytoad Ltd | Wholesale & retail | 2022 |
| Smokin Rooster Ltd | Hospitality | 2011 |
| Smooth Cabs Limited | Transport & logistics | 2021 |
| Smoothskies Limited | Professional & scientific | 2023 |
| Smotc Limited | Wholesale & retail | 2013 |
| Smrjasw Ltd | Information & communication | 2023 |
| Smslogin Ltd | Information & communication | 2025 |
| Smudger Associates Limited | Real estate | 2011 |
| SMW Capital Ltd | Real estate | 2026 |
| SMW Developments Ltd | Real estate | 2022 |
| Snach Consulting Limited | Information & communication | 2020 |
| Snach Properties Limited | Real estate | 2022 |
| Snacks 204 Ltd | Wholesale & retail | 2026 |
| Snake Motorcycles Limited | Extraterritorial | 2009 |
| Snap Media Limited | Professional & scientific | 2025 |
| Snap Startups Limited | Administrative & support | 2023 |
| Snap Trends Ltd | Wholesale & retail | 2025 |
| Snapfin Limited | Information & communication | 2013 |
| Snaps Photo Services Limited | Professional & scientific | 1991 |
| SNB Autoz Ltd | Wholesale & retail | 2025 |
| Sneak Peak Restore Ltd. | Other services | 2025 |
| Sneaker-Shine Limited | Wholesale & retail | 2025 |
| SNH Tech Ltd | Real estate | 2023 |
| SNK Consulting Limited | Wholesale & retail | 2009 |
| Snooks Tiling Limited | Construction | 2011 |
| Snoveil Limited | Real estate | 2025 |
| Snow & Sons Electrical Ltd | Construction | 2019 |
| Snow Showers Ltd | Health & social care | 2019 |
| SO Business Consultancy Ltd | Professional & scientific | 2026 |
| SO GAY Gifts Ltd | Wholesale & retail | 2026 |
| SO GAY Weddings Ltd | Wholesale & retail | 2026 |
| SO Kitchens & Bathrooms Ltd | Wholesale & retail | 2020 |
| SO Plus Co Limited | Information & communication | 2019 |
| SO Radio Limited | Information & communication | 2017 |
| Soapaholic Ltd | Administrative & support | 2025 |
| Soben Properties Limited | Real estate | 2003 |
| Sobey Group Ltd | Households | 2025 |
| Sobo 2023 Ltd | Hospitality | 2023 |
| Socal Gym Ltd | Arts & recreation | 2020 |
| Socasa Ltd | Professional & scientific | 2024 |
| Social Innovation Media Ltd | Professional & scientific | 2013 |
| Social Orthopedist Ltd | Manufacturing | 2025 |
| Socialspark Productions Ltd | Information & communication | 2025 |
| Society for Storytelling | Education | 1995 |
| Society Homes LLP | | 2007 |
| Socmintech LLP | | 2024 |
| Soco Management Ltd | Real estate | 2025 |
| Socotraco Ltd | Financial services | 2023 |
| Socreative Technology Ltd | Information & communication | 2021 |
| Sofanatic Ltd | Wholesale & retail | 2023 |