| Regency House Residential Home Limited | Other services | 2002 |
| Regenerate (2016) Limited | Wholesale & retail | 2016 |
| Regional Engineers Distributors Group Limited | Professional & scientific | 1983 |
| Regista Analytics CYF | Information & communication | 2026 |
| Reinspire.Co.Uk Limited | Wholesale & retail | 2004 |
| Reneuroble Ltd | Other services | 2025 |
| Renew & Restore Ltd | Construction | 2024 |
| Renovate Developments Limited | Construction | 2021 |
| Rent Easy Properties Limited | Real estate | 2025 |
| Rental 123 Ltd | Real estate | 2024 |
| Renz Investments Ltd | Real estate | 2023 |
| Rept Battero UK Ltd | Manufacturing | 2026 |
| Rescrete Ltd | Construction | 2026 |
| Resin Pro Surfacing Ltd | Construction | 2025 |
| Resse Automation Technology Co., Ltd | Wholesale & retail | 2014 |
| Revive Contract Services Limited | Construction | 2019 |
| Rewsa Ltd | Real estate | 2019 |
| RGP Events Ltd | Wholesale & retail | 2022 |
| RH Electrical and Solar Solutions Ltd | Construction | 2026 |
| RH Home Installations Limited | Construction | 2011 |
| Rhi's Cafe Limited | Hospitality | 2017 |
| Rhiannon Bowen Ltd | Health & social care | 2022 |
| Rhoc Holdings Limited | Information & communication | 2026 |
| Rhondda Brown Trout Ltd | Hospitality | 2024 |
| Rhondda Grey Limited | Real estate | 2021 |
| Rhondda Tiles Discount Centre Ltd | Wholesale & retail | 2006 |
| Rhonddapubs Ltd | Hospitality | 2025 |
| Rhoose DC Ltd | Health & social care | 2024 |
| Rhydyfelin RFC Limited | Arts & recreation | 2017 |
| Rhyming Horse Audio Ltd | Information & communication | 2021 |
| Riczac Ltd | Wholesale & retail | 2024 |
| Rise Contracting Services Limited | Other services | 2021 |
| Riverside Garage (Tonyrefail) Limited | Manufacturing | 2011 |
| Riverview Properties (Pontypridd) LLP | | 2025 |
| Riverview Residential Ltd | Real estate | 2023 |
| Rixingyi Limited | Wholesale & retail | 2023 |
| Rizq&Rise Ltd | Administrative & support | 2025 |
| RJM Pharma Limited | Wholesale & retail | 2025 |
| RJQ Limited | Other services | 2018 |
| RJW Properties (Newport) Ltd | Real estate | 2024 |
| Rmlh Global Limited | Wholesale & retail | 2025 |
| Road Runner Motor Parts Ltd | Wholesale & retail | 2003 |
| Robbins & Brown Limited | Real estate | 1977 |
| Robbwl Ltd | Hospitality | 2025 |
| Roberttown Service Station Limited | Other services | 2007 |
| Rock at Work Ltd | Arts & recreation | 2014 |
| Rock Quantity Surveyors Ltd | Professional & scientific | 2021 |
| Rocket Capital Ltd | Real estate | 2010 |
| Rocket Renovation Ltd | Real estate | 2017 |
| Roger Geraghty & Sons Ltd | Wholesale & retail | 2024 |
| ROI Consulting Limited | Professional & scientific | 2011 |
| Rolando Limited | Transport & logistics | 2025 |
| Roly Poly Events Limited | Hospitality | 2025 |
| Rong WO Co., Ltd | Wholesale & retail | 2025 |
| Roofbeck Ltd | Construction | 2004 |
| Root 66 Hairdressers Limited | Other services | 2007 |
| Ross Pearce Ltd | Administrative & support | 2012 |
| Round Tings Distribution Ltd | Wholesale & retail | 2024 |
| Roundhouse Builders Limited | Construction | 2019 |
| RP Choices Properties Ltd | Real estate | 2021 |
| RP6 Management Services Ltd | Information & communication | 2024 |
| RPJ Electrical Limited | Construction | 2010 |
| RR Davies Limited | Water & waste | 2006 |
| RS & KL Services Limited | Health & social care | 2014 |
| RSS (Ready Steady SET Concrete Supplies) Ltd | Transport & logistics | 2017 |
| RTB Decorating Limited | Construction | 2002 |
| RUA - Salon & Wellness Hub Ltd | Other services | 2026 |
| Ruige&Lou Art and Craft Limited | Manufacturing | 2024 |
| Running Punks Ltd | Wholesale & retail | 2022 |
| RWH Plastering Ltd | Construction | 2022 |
| RY Ace Property Investments Ltd | Hospitality | 2023 |
| Ryan Property Holdings Limited | Hospitality | 2018 |
| Ryan Thomas Plumbing & Heating Limited | Construction | 2016 |
| S & T LEE Development Limited | Real estate | 2024 |
| S E Batten Limited | Construction | 2022 |
| S Fynes Healthcare Ltd | Health & social care | 2023 |
| S Russell Plastering & General Building Ltd | Construction | 2007 |
| S T Plastering Ltd | Construction | 2015 |
| S&B Bespoke Care Services Ltd | Hospitality | 2018 |
| S&J Modern Spaces Limited | Real estate | 2024 |
| S. Adams Services Limited | Construction | 2018 |
| S.Brennan H&T Ltd | Health & social care | 2018 |
| S1 Gourp Ltd | Information & communication | 2019 |
| S360 Holdings Limited | Real estate | 2019 |
| Saeth Sportswear Ltd | Manufacturing | 2026 |
| Safetyform Limited | Extraterritorial | 2018 |
| Safeway Chemicals Co., Ltd | Wholesale & retail | 2014 |
| SAI News Ltd | Wholesale & retail | 2017 |
| Saibaike Ltd | Wholesale & retail | 2024 |
| Samurai Project Services Ltd | Information & communication | 2019 |
| Sanau Socks Ltd | Wholesale & retail | 2025 |
| Sans Peur Limited | Professional & scientific | 2011 |
| Sarge's Yard'N'Garden Ltd | Administrative & support | 2025 |
| Satin Reverie Ltd | Wholesale & retail | 2025 |
| Sauvage Consultancy & Investments Ltd | Professional & scientific | 2021 |
| Sb.Therock Limited | Hospitality | 2026 |
| Scarfe Property Limited | Real estate | 2025 |
| Scarfe Scaffolding Limited | Wholesale & retail | 1999 |
| Scarfe Scaffolding Services Limited | Construction | 2021 |
| Scarflo Couriers Limited | Transport & logistics | 2023 |