| Dynamic Extractions Limited | Professional & scientific | 2001 |
| Dynamic Reliability Solutions Limited | Professional & scientific | 2017 |
| E & E Billings Ltd | Hospitality | 2022 |
| E Daniel Property Developments Ltd | Real estate | 2024 |
| E.T.M. Steel Fabrications Limited | Professional & scientific | 1972 |
| Earthclear Limited | Extraterritorial | 1997 |
| Eaton Daniels Ltd | Wholesale & retail | 2025 |
| EB Tattoo Designs Ltd | Other services | 2025 |
| Eclipse and Embers Ltd | Wholesale & retail | 2025 |
| Edau Sewing Room Ltd | Extraterritorial | 2021 |
| Eden Downes Ltd | Wholesale & retail | 2025 |
| Edmunds & Co Logistics Ltd | Extraterritorial | 2023 |
| Edward FOX Ltd | Wholesale & retail | 2025 |
| Edwards Contractors Group Ltd | Construction | 2026 |
| Edwards Electrical (EEC) Ltd | Construction | 2020 |
| EL Greengo’S Garms Ltd | Wholesale & retail | 2025 |
| EL Mejor Motors Ltd | Wholesale & retail | 2025 |
| Electric Pocket Limited | Information & communication | 2000 |
| Electro Magnetic Products Limited | Manufacturing | 1998 |
| Elen Pugh Ltd | Financial services | 2019 |
| Elgin Saxon Ltd | Wholesale & retail | 2025 |
| Eliazer Ltd | Health & social care | 2023 |
| Elite Aircon Limited | Construction | 2020 |
| Elite Arches Limited | Manufacturing | 2018 |
| Elite Growth Alliance Ltd | Professional & scientific | 2026 |
| Elite Residential Property Management Ltd | Real estate | 2018 |
| Ellevue Manors Ltd | Wholesale & retail | 2025 |
| Ellig Holdings Limited | Professional & scientific | 2025 |
| Eloquent Elephant Ltd | Information & communication | 2023 |
| Elston Road 01/01/1971 Limited | Extraterritorial | 2014 |
| Emma Miller Ltd | Financial services | 2024 |
| Emsworth Cannon Ltd | Wholesale & retail | 2025 |
| Enbee Pro Limited | | 1986 |
| Endles Hugg Ltd | Wholesale & retail | 2025 |
| Energy-Id Ltd | Professional & scientific | 2020 |
| Enfys Property Ltd | Construction | 2018 |
| Engineering Wales Limited | Manufacturing | 2000 |
| Epworth Knole Ltd | Wholesale & retail | 2025 |
| Equine Therapy Center C.I.C. | Health & social care | 2016 |
| Equine Therapy Center Management Ltd | Other services | 2022 |
| Esprit Automotive Ltd | Wholesale & retail | 2024 |
| Estac Contracts Ltd | Construction | 2020 |
| Estac Property Limited | Real estate | 2023 |
| Esteem Money Limited | Financial services | 2008 |
| Esther Morgan Oral Hygienist Limited | Health & social care | 2015 |
| Evans Marsh Ltd | Wholesale & retail | 2025 |
| Evans Quality Ltd | Professional & scientific | 2016 |
| Eve's Pole and Yoga Ltd | Arts & recreation | 2022 |
| Event Prop Shop Ltd | Arts & recreation | 2017 |
| Everett Masson & Furby (South and West Wales) Limited | Real estate | 2005 |
| Evolve Environmental Ltd | Administrative & support | 2024 |
| Excavators Wales Limited | Construction | 1980 |
| Excel Fish Bar Limited | Hospitality | 2006 |
| Exclusive Motors (South Wales) Limited | Wholesale & retail | 2016 |
| Exile Techno Events Ltd | Arts & recreation | 2025 |
| F & J Plant Hire Limited | Construction | 2002 |
| FAE Adora Limited | Health & social care | 2024 |
| Farm & Fork Restaurant Private Ltd | Hospitality | 2026 |
| Fascar EV Ltd | Manufacturing | 2019 |
| Fashions Online Ltd | Wholesale & retail | 2023 |
| Faucets (Northern) Limited | Manufacturing | 2012 |
| Faucets Group Limited | Professional & scientific | 2022 |
| Feenix Group Ltd | Construction | 2025 |
| Fellmeadow Woods Ltd | Wholesale & retail | 2025 |
| FEN and Folly Ltd | Health & social care | 2025 |
| Fernandes & Co Ltd | Construction | 2015 |
| FHD Holdings Ltd | Financial services | 2024 |
| Fighting Fit Torfaen | Arts & recreation | 2012 |
| Filton Bridge Ltd | Wholesale & retail | 2025 |
| Filton North Ltd | Wholesale & retail | 2025 |
| FIN Properties Ltd | Real estate | 2018 |
| Finance Detective Ltd | Administrative & support | 2005 |
| Finn Moira Ltd | Wholesale & retail | 2024 |
| Firepower Sport Limited | Manufacturing | 2012 |
| Firgrove Nelson Ltd | Wholesale & retail | 2025 |
| Fit a Frame Ltd | Manufacturing | 2025 |
| Fixco/Embro Ltd | Administrative & support | 2025 |
| Flame PIT Grill Ltd | Hospitality | 2025 |
| Flaxley Deppe Ltd | Wholesale & retail | 2025 |
| Floathaus Limited | Other services | 2025 |
| FLS Group Limited | Financial services | 2025 |
| FLS Holdco Limited | Financial services | 2021 |
| Fonthill Ascot Ltd | Wholesale & retail | 2025 |
| Foodie Shack & Deli Ltd Ltd | Hospitality | 2025 |
| Foodie Shackk Limited | Hospitality | 2025 |
| FOR Your Care Services Ltd | Other services | 2017 |
| Ford Property Group Ltd | Real estate | 2022 |
| Forestry Equipment Ltd | Wholesale & retail | 2019 |
| Forge & Fable Ltd | Wholesale & retail | 2025 |
| Forge ROW Residents Management Limited | Households | 1987 |
| Forgeside RFC Limited | Arts & recreation | 2018 |
| Forrestford Engineering Limited | Manufacturing | 1970 |
| Four Seasons Caterers Limited | Hospitality | 2007 |
| Fradd Tutoring Ltd | Education | 2020 |
| Francis Automotive Solutions Ltd | Wholesale & retail | 2022 |
| Francis Lytte Ltd | Wholesale & retail | 2025 |
| Francismel Limited | Health & social care | 2019 |
| Frog Bikes Distribution Limited | Manufacturing | 2026 |
| Frog Bikes Factory Limited | Real estate | 2026 |
| Frog Bikes Holdings Limited | Financial services | 2026 |