| Qixi Limited | Hospitality | 2021 |
| QJ Property Ltd | Real estate | 2026 |
| QLT Consulting Ltd | Real estate | 2011 |
| QSM Services (SW) Ltd | Professional & scientific | 2017 |
| Qspm Consultants LLP | | 2013 |
| Qsre Ltd | Professional & scientific | 2024 |
| Quadrant Quay Plot Management Company Limited | Households | 2014 |
| Quadtech UK Limited | Manufacturing | 2002 |
| Quality Appointers Limited | Administrative & support | 2015 |
| Quality Component Engineering Limited | Manufacturing | 1998 |
| Quality Safety Training Ltd | Education | 2010 |
| QUALITYINCARE4U Ltd | Health & social care | 2022 |
| Quantity Surveying SW Ltd | Professional & scientific | 2022 |
| Quantock Engineering Services Ltd | Construction | 2025 |
| Quantra Consulting Limited | Information & communication | 2016 |
| Quantum Construction & Maintenance Holdings Limited | Financial services | 2022 |
| Quantum Electrical SW Ltd | Construction | 2023 |
| Quantum Group SW Ltd | Construction | 2025 |
| Quantum Theory Ltd | Information & communication | 2018 |
| Quarks and Charms Limited | Information & communication | 2019 |
| Quarterdeck Systems Ltd | Information & communication | 2006 |
| Quartex Technologies (UK) Ltd | Information & communication | 2015 |
| Quattro Projects Limited | Financial services | 2012 |
| Quay 33 Lettings Limited | Real estate | 2022 |
| Quay 33 Ltd | Extraterritorial | 2013 |
| Quay Dental Solutions Limited | Health & social care | 2020 |
| Quay Plymouth Limited | Hospitality | 2021 |
| Quay West Productions Limited | Information & communication | 2025 |
| Quayside Hospitality Limited | Hospitality | 2020 |
| Quayside Property Management Services Ltd | Real estate | 2017 |
| Quaysideplymouth Ltd | Hospitality | 2019 |
| Queen BEE Production Community Interest Company | Information & communication | 2025 |
| Queen's Court (Plymouth) Limited | Households | 1989 |
| Queer OUT Loud CIC | Other services | 2024 |
| Querky Construction Limited | Manufacturing | 2024 |
| Questionable Quality Ltd. | Information & communication | 2014 |
| Quick FIX Mobiles & Accessories Ltd | Other services | 2014 |
| Quick I FIX Ltd | Other services | 2023 |
| Quick Liquids Limited | Wholesale & retail | 2016 |
| Quick Phone FIX Limited | Wholesale & retail | 2026 |
| Quickstore (Saltash) Ltd | Real estate | 2011 |
| Quinquevir Limited | Financial services | 2011 |
| Quirky Pineapple Ltd | Other services | 2023 |
| Quoinstone Developments Ltd | Financial services | 2015 |
| Quoinstone Droskyn Ltd | Construction | 2018 |
| Quoinstone Lanner Ltd | Construction | 2022 |
| Quoinstone Meadows Ltd | Construction | 2019 |
| Quoinstone Treleigh Ltd | Construction | 2016 |
| Quorn & Loughborough Glass Limited | Manufacturing | 2017 |
| R & H Vehicle Repairs Ltd | Wholesale & retail | 2024 |
| R & W Property & Lettings Limited | Hospitality | 2006 |
| R and J Properties (Wrangaton) Limited | Real estate | 2025 |
| R B Construction (South West) Limited | Construction | 2015 |
| R Chamberlain Fishing and Diving Ltd | Agriculture & fishing | 2026 |
| R F Buildings and Construction Limited | Construction | 2013 |
| R H Plastering & Building Services Ltd | Construction | 2022 |
| R Heat Ltd | Construction | 2023 |
| R J & N J Williams Limited | Extraterritorial | 1982 |
| R J C Contract Carpenters Limited | Manufacturing | 2015 |
| R J Property Developments SW Ltd | Construction | 2021 |
| R J T Property Maintenance Ltd | Construction | 2024 |
| R J Walker (Newquay) Limited | Construction | 2013 |
| R L Motor Services Limited | Wholesale & retail | 2010 |
| R M Builders & Contractors Limited | Construction | 2010 |
| R M Developments (Southwest) Limited | Construction | 2011 |
| R Robilliard Limited | Professional & scientific | 2025 |
| R Shrestha (SW) Ltd | Health & social care | 2022 |
| R T J Martin Holdings Limited | Administrative & support | 2008 |
| R T J Martin Limited | Construction | 1996 |
| R West & SON Limited | Manufacturing | 2011 |
| R&C Berry Limited | Administrative & support | 2009 |
| R&L Roofing Services Limited | Construction | 2026 |
| R&R Auto Salvage Ltd | Other services | 2018 |
| R&RK9SECURITYSERVICES Ltd | Administrative & support | 2026 |
| R&S Thai Kitchen Ltd | Hospitality | 2026 |
| R&S Waste Management Ltd | Water & waste | 2025 |
| R. & S. Motors Limited | Wholesale & retail | 1987 |
| R. Burbage Haulage Limited | Transport & logistics | 2003 |
| R. Goodchild Limited | Professional & scientific | 2022 |
| R. Harper Limited | Real estate | 1962 |
| R. M. Carpenters Ltd | Construction | 2017 |
| R. Westlake & Sons Limited | Information & communication | 1986 |
| R.B.C. Properties Limited | Professional & scientific | 2000 |
| R.E.D. (S.W.) Limited | Construction | 2001 |
| R.J.B. Garden Services Ltd | Administrative & support | 2007 |
| R.J.T Communications Limited | Professional & scientific | 2015 |
| R.M.P Electrical Limited | Construction | 2017 |
| R.P. & S Heywood (Haulage) Limited | Water & waste | 1991 |
| R.S. Body & Company Limited | Administrative & support | 1971 |
| RA Flat Roofing Limited | Construction | 2012 |
| Rabbit Growth Partners Limited | Administrative & support | 2026 |
| Raceoak Limited | Hospitality | 1977 |
| Rack Rocket Limited | Information & communication | 2015 |
| Radford Freehold Ltd | Real estate | 2019 |
| Radholdings Limited | Financial services | 2016 |
| Radiologyconsulting Ltd | Professional & scientific | 2026 |
| Radly Ltd | Financial services | 2023 |
| Radman DAN Limited | Professional & scientific | 2012 |
| Radmore Holdings Limited | Construction | 2019 |
| Radsafety Limited | Professional & scientific | 2006 |