| Cardinal Legacy Holdings Ltd | Manufacturing | 2026 |
| Care Angels Healthcare Ltd | Health & social care | 2024 |
| Care Projects (SW) Ltd | Construction | 2021 |
| Care Warehouse Ltd | Health & social care | 2020 |
| Careaider Ltd | Administrative & support | 2022 |
| CARELINE24 Services Ltd | Health & social care | 2025 |
| Carew (Holdings) Ltd | Professional & scientific | 2012 |
| Carew Wharf Management Company Limited | Households | 1988 |
| Carl's Boxing Stable CIC | Arts & recreation | 2023 |
| Carla & Co (SW) Limited | Professional & scientific | 2023 |
| Carlson Holdings Limited | Information & communication | 2016 |
| Carlson Media Ltd | Professional & scientific | 2017 |
| Carlton Cleaning Contractors Limited | Administrative & support | 2003 |
| Carlton Plastics (SW) Ltd | Construction | 2011 |
| Carol Dantas Services Ltd | Administrative & support | 2025 |
| Carol Massey Ltd | Wholesale & retail | 2021 |
| Caroline Court Management Company Limited | Households | 2004 |
| Carolney Ltd | Extraterritorial | 2024 |
| Carolyn Croft Family Law Services Limited | Other services | 2021 |
| Carpet 1ST Plymouth Installers Ltd | Wholesale & retail | 2022 |
| Carpet 1ST Plymouth Ltd | Wholesale & retail | 2001 |
| Carpets Direct South West Limited | Wholesale & retail | 2021 |
| Carrier Controls Limited | Construction | 2005 |
| Carrier Pension Trustee Limited | Financial services | 1993 |
| Carrier Solutions UK Ltd. | Construction | 1999 |
| Carringtinoo's Ltd | Hospitality | 2020 |
| Carry on Camping Ltd | Hospitality | 2025 |
| Cart Smart Limited | Wholesale & retail | 2026 |
| Cartay Developments Limited | Construction | 2012 |
| Cartby Digital Ltd | Information & communication | 2026 |
| Caruana.Tech Limited | Information & communication | 2025 |
| Casa Health Network CIC | Wholesale & retail | 2024 |
| Casa Music Group Limited | Arts & recreation | 2018 |
| Casaboa Ltd | Real estate | 2022 |
| Casalivin Developments Ltd | Real estate | 2024 |
| Casalivin Ltd | Professional & scientific | 2015 |
| Case Craft UK Ltd | Wholesale & retail | 2026 |
| Cashless PAY UK Limited | Financial services | 2023 |
| Caspex LLP | | 2007 |
| Cassie Bespoke Upholstery Limited | Manufacturing | 2023 |
| Castellanus Properties Limited | Households | 2024 |
| Castle Plumbing & Heating Limited | Construction | 1997 |
| Castledyke Management Company Limited | Households | 2000 |
| Catalina Villas Management Limited | Households | 2002 |
| Catalysts for Emerging Tech Ltd. | Information & communication | 2024 |
| Catered Limited | Hospitality | 2014 |
| Catherine Place Limited | Real estate | 2022 |
| Cattedown Regeneration Limited | Construction | 1995 |
| Cattedown Repair Centre Ltd | Wholesale & retail | 2020 |
| Cattedown Trade Centre Limited | Wholesale & retail | 2017 |
| Cave & Kilmartin Group Limited | Real estate | 1979 |
| Caversham Marine Limited | Professional & scientific | 2003 |
| Cavivac Ltd | Administrative & support | 2018 |
| Cawseway Electrics & Alarms Ltd | Construction | 2025 |
| CB Industrial Heating Ltd | Construction | 2020 |
| CB Property Services Limited | Real estate | 2005 |
| CBA Freeholders Limited | Households | 2023 |
| CBB Systems Limited | Professional & scientific | 2019 |
| CBE Group Holdings Limited | Financial services | 2025 |
| CBE SW Group Ltd | Financial services | 2023 |
| Cbmairsoft Ltd | Wholesale & retail | 2025 |
| Cbmreliability Ltd | Other services | 2026 |
| CC & S Holdings Limited | Financial services | 2023 |
| CC Callaway Mortgages Limited | Financial services | 2023 |
| CC Financial Limited | Financial services | 2024 |
| CCK Developments Ltd | Construction | 2022 |
| CCS Commercial Cleaning Ltd | Administrative & support | 2023 |
| CCS South West Ltd | Professional & scientific | 2019 |
| CD Cooke Property Limited | Households | 2023 |
| CD Lease Holdings Limited | Financial services | 2024 |
| CD5 Ltd | Professional & scientific | 2023 |
| CDI Waterproofing Services Ltd | Construction | 2021 |
| CDM & Safety Services Limited | Construction | 2022 |
| Cdocc Ltd | Hospitality | 2025 |
| Cdperformance Ltd | Other services | 2018 |
| CDS (Superstores International) Limited | Wholesale & retail | 1992 |
| CDS Group Services Limited | Construction | 2005 |
| CEC Electrical and Building Maintenance Contractors Limited | Manufacturing | 2012 |
| Cece's Everything Syrups Ltd | Manufacturing | 2025 |
| Cecorp International Limited | Wholesale & retail | 2017 |
| Cedar MOR Property Ltd | Real estate | 2023 |
| Cedar Park Bovisand (Management) Limited | Real estate | 1992 |
| Cedarcare (SE) Ltd | Health & social care | 1994 |
| CEE Group Ltd | Construction | 2021 |
| Celecs Ltd | Manufacturing | 2025 |
| Celonia Ceylon Ltd | Wholesale & retail | 2026 |
| Celtic Barbers Limited | Other services | 2014 |
| Celtic Canines Ltd | Education | 2023 |
| Celtic Marine Services Limited | Professional & scientific | 2022 |
| Celtic Shores Investments Ltd | Financial services | 2018 |
| Celtic Shores Management Limited | Households | 2003 |
| Cenda Medical Ltd | Health & social care | 2025 |
| Central Park Dental Practice Limited | Health & social care | 2009 |
| Central Park Towers Management RTM Company Limited | Households | 2019 |
| Central Plymouth Apartments Ltd | Hospitality | 2021 |
| Centraven Ltd | Real estate | 2018 |
| Centrelink Management Ltd | Professional & scientific | 2012 |
| Century Twenty Limited | Administrative & support | 2019 |
| CEO Group Limited | Professional & scientific | 2008 |
| CEO4ART Limited | Wholesale & retail | 2020 |