| Uresh Mini Market Ltd | Wholesale & retail | 2018 |
| Urogyn Operations Ltd | Health & social care | 2021 |
| Ursaursa Ltd | Health & social care | 2026 |
| Usman Nasir Ltd | Wholesale & retail | 2025 |
| UTM Consultants Ltd | Administrative & support | 2016 |
| Utopia Consultant Ltd | Professional & scientific | 2023 |
| Utopia Developments (2026) Limited | Construction | 2026 |
| Utopia Living Ltd | Construction | 2023 |
| V & L (Residents) Management Limited | Households | 1989 |
| V and T Homes Limited | Construction | 2014 |
| V E Morcom Properties Limited | Real estate | 2002 |
| V G Developments Ltd | Construction | 2007 |
| V&Sj Property Ltd | Hospitality | 2013 |
| Vacant Places Limited | Administrative & support | 2018 |
| Valdon Developments Limited | Construction | 2007 |
| Valentino Lighting Co Ltd | Manufacturing | 2025 |
| Valhaas Ltd | Construction | 2019 |
| Valknut Automation Ltd | Professional & scientific | 2015 |
| Valknut Consultancy Ltd | Extraterritorial | 2018 |
| Valknut Holdings Ltd | Financial services | 2018 |
| Valknut Training Ltd | Extraterritorial | 2019 |
| Valle Construction Limited | Construction | 2006 |
| Valletort Plymouth Management Company Limited | Households | 2007 |
| Valley Court Crownhill Plymouth Management Limited | Households | 2004 |
| Valley Diamond Car Wash Ltd | Administrative & support | 2017 |
| Valley Road Hand Car Wash Ltd | Administrative & support | 2023 |
| Valley View Elburton Land Ltd | Construction | 2025 |
| Vallis House Limited | Real estate | 2021 |
| Vallis House Management Limited | Real estate | 2024 |
| Valtura Payments Group Ltd. | Other services | 2025 |
| Vams Holidays Limited | Real estate | 2021 |
| Van Cabin Air Beds Ltd | Wholesale & retail | 2025 |
| Vanduff Ltd | Real estate | 2018 |
| Vanelly Ltd | Construction | 2016 |
| Vanguard Electrical Systems Ltd | Construction | 2023 |
| Vanishing Point Marine Limited | Other services | 2012 |
| Vanquish Imagery Services (UK) Group Ltd | Administrative & support | 2021 |
| Vanro Properties Limited | Real estate | 2024 |
| Vanstone Medical Ltd | Health & social care | 2019 |
| Vantage Junction Consulting Ltd | Information & communication | 2026 |
| Vanver Ltd | Real estate | 2021 |
| Vape Land 1 Ltd | Wholesale & retail | 2025 |
| Vardo Architecture Limited | Professional & scientific | 2022 |
| Vasara Limited | Wholesale & retail | 2005 |
| Vaughan's Academy Limited | Other services | 2025 |
| Vauxdale Limited | Financial services | 2024 |
| Vauxhall Street Holdings Limited | Extraterritorial | 2018 |
| Vauxhall Street Plymouth Management 2006 Limited | Real estate | 2006 |
| VBC Courier Ltd | Transport & logistics | 2019 |
| Vbmcleaning Limited | Administrative & support | 2024 |
| Vector Consulting Associates Ltd | Financial services | 2023 |
| Vegvísir Ltd | Education | 2025 |
| Vehicle Retrim Services Ltd | Wholesale & retail | 2015 |
| Vela Flowers Limited | Wholesale & retail | 2018 |
| Vela Pilates Malvern Ltd | Arts & recreation | 2026 |
| Velo Collective Ltd | Professional & scientific | 2026 |
| Velo-Smith Ltd | Wholesale & retail | 2011 |
| Velorie London Limited | Wholesale & retail | 2025 |
| Veltek Ltd | Information & communication | 2016 |
| Vemir Ltd | Wholesale & retail | 2025 |
| Vendoor Deliveries Ltd | Financial services | 2025 |
| Venetia Ltd | Financial services | 2022 |
| Venkatesha Retail Limited | Wholesale & retail | 2025 |
| Venn Business Network Limited | Administrative & support | 2018 |
| Venn Holdings South West Limited | Real estate | 2019 |
| Ventboys Ltd | Administrative & support | 2026 |
| Ventro Holdings Ltd | Financial services | 2016 |
| Ventro Ltd | Public administration | 2013 |
| Venture Risk Management Ltd | Administrative & support | 2023 |
| Venue Vision Consultancy Ltd | Public administration | 2023 |
| Veracity Asset Transformation Service Limited | Financial services | 2010 |
| Verbury Limited | Information & communication | 2016 |
| Verden Close Management Limited | Households | 2013 |
| Verlata Consulting Limited | Information & communication | 2021 |
| Verneos Limited | Water & waste | 2010 |
| Vernon Property Investments Ltd | Construction | 2024 |
| Versed Carers Ltd | Other services | 2017 |
| Versedguards Services Limited | Administrative & support | 2018 |
| Veselle Ltd | Wholesale & retail | 2025 |
| Vessel Architects Ltd | Professional & scientific | 2021 |
| Vessel Social Work Services Ltd | Health & social care | 2021 |
| Vetboss Ltd | Information & communication | 2013 |
| Veterans Voyage CIC | Health & social care | 2021 |
| Vetgrad Ltd | Information & communication | 2010 |
| VIA Mare Seafood Limited | Wholesale & retail | 2026 |
| Vibe Accounting Ltd | Professional & scientific | 2019 |
| Viburnum (Okehampton) Limited | Construction | 2025 |
| Viburnum Developments Ltd | Construction | 2025 |
| Viburnum Estates Ltd | Financial services | 2022 |
| Vickery Holman Limited | Professional & scientific | 1994 |
| Victor Grange Limited | Construction | 1998 |
| Victoria Creber Limited | Professional & scientific | 2022 |
| Victoria Group Holdings Limited | Professional & scientific | 2009 |
| Victoria Group Investments Limited | Financial services | 2024 |
| Victoria House Developments Limited | Construction | 2016 |
| Victoria House Lyme Regis Management Limited | Real estate | 2022 |
| Victoria House Property Management Limited | Real estate | 2025 |
| Victoria House Studios Ltd | Information & communication | 2012 |
| Victoria Hurth Ltd | Extraterritorial | 2022 |
| Victoria Ports Limited | Extraterritorial | 2017 |