| Direction Real Estate Investment Limited | Hospitality | 2014 |
| Discovery Music Distribution Limited | Wholesale & retail | 2018 |
| Distributed Solutions UK Limited | Information & communication | 2015 |
| Disturbed Clothing Limited | Wholesale & retail | 2014 |
| Divaa Retail Limited | Wholesale & retail | 2023 |
| Diverse City Solutions Ltd | Administrative & support | 2024 |
| Diviine Enterprise International Limited | Manufacturing | 2018 |
| Divine Rock Care Limited | Health & social care | 2023 |
| Djcb Limited | Construction | 2024 |
| DJP Healthcare Limited | Wholesale & retail | 2004 |
| Djpj Management Ltd | Real estate | 2022 |
| DJW Cables, Components & Recycling Limited | Water & waste | 2017 |
| DJW Electric Services Ltd | Construction | 2008 |
| DKA Constructions Ltd | Construction | 2019 |
| DKP Builders and Interiors Ltd | Construction | 2026 |
| DKS Holdings Ltd | Real estate | 2023 |
| DL Plus Limited | Construction | 2014 |
| DM Cakes Limited | Wholesale & retail | 2019 |
| DM GP Services Limited | Health & social care | 2022 |
| DM Painting & Decorating Services Limited | Construction | 2012 |
| DM Raja (Investments) Limited | Real estate | 2001 |
| Dm&H Ltd | Water & waste | 2025 |
| DMG7 Management Ltd | Administrative & support | 2020 |
| DMJ Solutions Ltd | Information & communication | 2024 |
| Dmje Ltd | Administrative & support | 2013 |
| Dna-Rda Limited | Construction | 2002 |
| DNR Holdings Limited | Real estate | 1991 |
| DNZ Surgery Ltd | Health & social care | 2021 |
| DO Trading Limited | Other services | 2018 |
| Docchealth Ltd | Health & social care | 2024 |
| Docleaf Leadership Limited | Professional & scientific | 2015 |
| Doctor Walji Limited | Health & social care | 2016 |
| Doddington Stores T/As One Stop Ltd | Wholesale & retail | 2015 |
| Dodhia Estates Limited | Real estate | 2022 |
| Dodia Developments Limited | Real estate | 2021 |
| Dodia Investments Limited | Real estate | 2023 |
| Dokal Developments Limited | Real estate | 2016 |
| Dokal Estates Limited | Real estate | 2013 |
| Dokal Investments Limited | Real estate | 2011 |
| Dolanland Limited | Professional & scientific | 1986 |
| Dolce Dimora Interiors Limited | Wholesale & retail | 2024 |
| Dollar Glen Consulting Limited | Information & communication | 2025 |
| Dolphin Holdings Limited | Real estate | 2020 |
| Dominic Honey Consulting Limited | Professional & scientific | 2017 |
| Dominick Consulting Ltd | Administrative & support | 2024 |
| Domus Digital Limited | Administrative & support | 2013 |
| Donarson Limited | Professional & scientific | 1983 |
| Donnybrook Limited | Real estate | 2020 |
| Doors & Floors Limited | Construction | 2024 |
| Doorstep Care Ltd | Health & social care | 2024 |
| Dormic UK Ltd | Real estate | 2016 |
| Dorset Heart Limited | Health & social care | 2016 |
| Doryn ST Ltd | Construction | 2014 |
| Doshian Consulting Ltd | Professional & scientific | 2014 |
| Double Pride Limited | Transport & logistics | 2010 |
| Doublemoon Limited | Wholesale & retail | 2007 |
| Doughlords Partners Limited | Financial services | 2025 |
| Douglas Collier Ltd | Professional & scientific | 1996 |
| Douglas Mowle Consulting Ltd | Professional & scientific | 2023 |
| Dowat Trading Ltd | Real estate | 2025 |
| Downlands Care Limited | Health & social care | 2001 |
| DP & Co Accountancy Services Limited | Professional & scientific | 2024 |
| DP Cyber Solutions Ltd | Information & communication | 2022 |
| DP Ekoproducts Ltd | Transport & logistics | 2015 |
| DPD Investments Limited | Real estate | 2015 |
| DPG Façade Ltd | Construction | 2023 |
| DPM Solutions Ltd | Real estate | 2022 |
| Dprp Investments Ltd | Real estate | 2021 |
| DR Deepan Vyas Limited | Other services | 2019 |
| DR Devji Ltd | Health & social care | 2022 |
| DR Ellie Ltd | Information & communication | 2013 |
| DR Helmy Consultancy Ltd | Professional & scientific | 2025 |
| DR Japanes Food Ltd | Hospitality | 2025 |
| DR Laurence Lever Ltd | Health & social care | 2019 |
| DR Niki Maini Limited | Health & social care | 2024 |
| DR Patel Ltd | Health & social care | 2020 |
| DR R3D Ltd | Health & social care | 2023 |
| DR. Richard Flint Obstetrics & Gynaecology Ltd | Health & social care | 2025 |
| Dradd Property Development Limited | Real estate | 2020 |
| Dragos Design Ltd | Construction | 2016 |
| Dran Limited | Administrative & support | 2025 |
| Dream Ayur Limited | Wholesale & retail | 2022 |
| Dream Homes Building Limited | Construction | 2011 |
| Dream TM Limited | Transport & logistics | 2016 |
| Dreambig Properties Ltd | Real estate | 2017 |
| Dreamy Caters Ltd | Hospitality | 2023 |
| DRF Limited | Health & social care | 2016 |
| DRH Construction Ltd | Construction | 2023 |
| DRM Cooling Ltd | Manufacturing | 2026 |
| Drms (Cctv) Limited | Administrative & support | 2001 |
| Drnl Consult Limited | Professional & scientific | 2009 |
| Drone Plan Ltd | Professional & scientific | 2022 |
| DRR Associates Ltd | Health & social care | 2025 |
| Drrayan Limited | Professional & scientific | 2018 |
| Drumcourt Limited | Households | 1986 |
| Dsda Investments Limited | Administrative & support | 2024 |
| DSJ Property Holdings Ltd | Real estate | 2026 |
| DSN Investments Limited | Real estate | 2018 |
| Dsyr Ltd | Health & social care | 2024 |
| DU Spirits Limited | Wholesale & retail | 2026 |