| R W M Marketing Limited | Professional & scientific | 2005 |
| R.M. Winscom Limited | Agriculture & fishing | 1947 |
| Radiation Analysis Services Limited | Professional & scientific | 2016 |
| Radipole Developments Limited | Construction | 2020 |
| Rainbow Roofing and Building Services Limited | Construction | 2007 |
| Ransom Publishing Limited | Information & communication | 1995 |
| RAW Bike Company Ltd | Manufacturing | 2021 |
| RAW Lion Management Ltd | Real estate | 2015 |
| RAW Trade Ltd | Extraterritorial | 2015 |
| RB Grass Ltd | Administrative & support | 2012 |
| RBD Builders Limited | Construction | 2019 |
| RBD Construction Ltd | Professional & scientific | 2024 |
| Rdrc Limited | Other services | 2021 |
| Rduncan Ltd | Health & social care | 2011 |
| Re-Envisioned Classic Cars Ltd | Wholesale & retail | 2021 |
| Re-Flex ODT Limited | Manufacturing | 2015 |
| Re-Format LLP | | 2007 |
| Reactivate Healthcare Ltd | Health & social care | 2008 |
| Reactivate Physiotherapy Limited | Health & social care | 2013 |
| Read Enviro Limited | Professional & scientific | 2023 |
| Real Bread and Refill Company Limited | Wholesale & retail | 2020 |
| Really Rich Insight Limited | Professional & scientific | 2021 |
| Rebecca Barnes Designs Ltd. | Administrative & support | 2016 |
| Rebitella Ltd | Information & communication | 2025 |
| Reboat Ltd | Manufacturing | 2022 |
| Red Aviation Limited | Transport & logistics | 2020 |
| Red Cat Authoring Limited | Arts & recreation | 2022 |
| Red Dock Limited | Professional & scientific | 2016 |
| Red Dog Holdings Limited | Wholesale & retail | 2018 |
| Red House Studio Limited(The) | Information & communication | 1985 |
| Red Tiger Consultancy Ltd | Professional & scientific | 2009 |
| Redfinch Software Limited | Information & communication | 2015 |
| Reevoo Limited | Information & communication | 2005 |
| Regal Brick & Stone Limited | Construction | 2019 |
| Regal Magpie Ltd | Wholesale & retail | 2015 |
| Regen Gosport Limited | Real estate | 2021 |
| Regina Cucina Ltd | Hospitality | 2012 |
| Relational Analytics Limited | Professional & scientific | 2026 |
| Remitex Ltd | Financial services | 2017 |
| Remotion Limited | Manufacturing | 2016 |
| Renard Associates Limited | Professional & scientific | 2002 |
| Renowned Renovations Limited | Construction | 2020 |
| Residence Interior Design Limited | Other services | 2007 |
| Resmundi Limited | Real estate | 2001 |
| Reubix Limited | Households | 2024 |
| Revalis Ltd | Health & social care | 2025 |
| Revive Consultants Ltd | Professional & scientific | 2010 |
| Revolution Physiotherapy Limited | Health & social care | 2013 |
| RG Carpentry & Building Limited | Construction | 2012 |
| Rhealto Limited | Professional & scientific | 1998 |
| Rialto Estates Ltd | Manufacturing | 2018 |
| Richard Dayman Associates Limited | Information & communication | 2011 |
| Richard Giles and Associates Ltd | Professional & scientific | 2011 |
| Richard MAY Limited | Construction | 2013 |
| Richards Photoprint Ltd | Manufacturing | 2013 |
| Richardsons (Harting) Limited | Extraterritorial | 2006 |
| Richardsons (Nyewood) Limited | Construction | 1989 |
| Richmond Walker Ltd | Professional & scientific | 2019 |
| Ridgeway Land Limited | Construction | 1999 |
| Ripe Investments Limited | Real estate | 2000 |
| Rivelle Group Ltd | Administrative & support | 2025 |
| Riverside Renobuild Limited | Construction | 2025 |
| Rizbrook Ltd | Wholesale & retail | 2021 |
| RL Sussex Limited | Real estate | 2017 |
| RLA Heating Ltd | Construction | 2025 |
| RM Properties & Developments Limited | Real estate | 2026 |
| Roar Events Limited | Arts & recreation | 2016 |
| ROB Elford Ltd | Arts & recreation | 2018 |
| Robert Bolt Limited | Administrative & support | 1971 |
| Robert Ingram HR Ltd | Professional & scientific | 2012 |
| Robert the Bruce Limited | Agriculture & fishing | 1997 |
| Robison & Co (IFA) Ltd | Financial services | 2003 |
| Robison & Co Limited | Financial services | 2003 |
| Robo Software Systems Limited | Information & communication | 1992 |
| ROD ERN Maritime Shipmanagement Ltd | Administrative & support | 2025 |
| Rogate Accident Repair Centre Limited | Wholesale & retail | 1998 |
| Rogate Village Stores Ltd | Wholesale & retail | 2020 |
| Rogue (GB) Limited | Professional & scientific | 2008 |
| Rokwear Ltd | Administrative & support | 2011 |
| Rollmarch Limited | Wholesale & retail | 1993 |
| Roman Concrete Limited | Construction | 2017 |
| Roman Contracts Limited | Construction | 2019 |
| Rookery and Orchard Farms Limited | Agriculture & fishing | 1990 |
| Rose Autumn Consulting Limited | Other services | 2023 |
| Rose Autumn Limited | Extraterritorial | 2022 |
| Ross & Mcewan Ltd | Other services | 2022 |
| Rosser Building & Landscapes Limited | Construction | 2008 |
| Rotherbrook Court Management Company Limited | Real estate | 2005 |
| Rotherbrook Financial Planning Limited | Professional & scientific | 2022 |
| Rotherburn Limited | Professional & scientific | 2012 |
| Rotherfield Utilities Limited | Construction | 2011 |
| Rotherley Management Company Limited | Households | 1997 |
| Rowswells Retail Ltd | Wholesale & retail | 2024 |
| Rozario Projects Ltd | Construction | 2025 |
| RRF Developments Ltd | Real estate | 2011 |
| Rsaulet Limited | Professional & scientific | 2025 |
| Rush Consult Limited | Other services | 2018 |
| Ryder Enterprises Brickyards Ltd | Real estate | 2016 |
| S B & SON Services Limited | Administrative & support | 2010 |
| S P G Autos Limited | Wholesale & retail | 1994 |