| Raptor Estates Limited | Hospitality | 2021 |
| Raptor Holdings (Cornwall) Limited | Financial services | 2024 |
| Raptor Scaffold Design & Consultancy Limited | Professional & scientific | 2012 |
| Raptors of Penwith Ltd | Agriculture & fishing | 2016 |
| Rdhm Holdings Limited | Financial services | 2025 |
| RDR Estates Limited Liability Partnership | | 2017 |
| Re:Design Urban Architecture Limited | Professional & scientific | 2004 |
| Recycling West Country Ltd | Water & waste | 2003 |
| Red Heart Tree CIC | Agriculture & fishing | 2020 |
| Red PIP Property Ltd | Real estate | 2024 |
| Redwing Contemporary Art C.I.C. | Arts & recreation | 2011 |
| Reef N Beef Ltd | Hospitality | 2023 |
| Refillution Ltd | Wholesale & retail | 2025 |
| Regenerative Food & Farming CIC | Agriculture & fishing | 2020 |
| Regent 1957 Limited | Extraterritorial | 2013 |
| Regent Green Service Centre Limited | Wholesale & retail | 2010 |
| Regent Joinery Works Limited | Construction | 2016 |
| Regent Penzance Ltd | Households | 2019 |
| Regent Property Management Ltd | Households | 2026 |
| Relton Technologies Limited | Information & communication | 2022 |
| Remake Cornwall Project CIC | Education | 2026 |
| Remedi Spirits Ltd | Manufacturing | 2020 |
| Renovo Projects Limited | Construction | 2013 |
| Research-I Ltd | Professional & scientific | 2017 |
| Reynolds & Slater Limited | Wholesale & retail | 2017 |
| RGJ Maritime & Motor Services Ltd | Agriculture & fishing | 2017 |
| Richard Gowan Consulting Limited | Professional & scientific | 2011 |
| Richards Property Solutions (SW) Ltd | Construction | 2026 |
| Richmond Commissioning Limited | Professional & scientific | 2010 |
| Rift Excursions Ltd | Arts & recreation | 2013 |
| Right on the Line Limited | Professional & scientific | 2000 |
| Right Steer Ltd | Professional & scientific | 2015 |
| Rimpfani Conservation Research CIC | Professional & scientific | 2026 |
| Riviera Apartments (Penzance) Management Company Limited | Households | 2001 |
| RLK Mining Consultants Limited | Mining & quarrying | 2018 |
| Robin Reeder Design Ltd | Information & communication | 2013 |
| Rock Pool Life C.I.C. | Professional & scientific | 2018 |
| Rockridge Porthcurno Limited | Construction | 2017 |
| Ronaldson Limited | Professional & scientific | 1996 |
| Ronin Boxing Ltd | Wholesale & retail | 2023 |
| Roschreel Ltd | Professional & scientific | 2024 |
| Roscoe Communications Limited | Professional & scientific | 2020 |
| Rose Terrace (Cornwall) Management Company Limited | Households | 2018 |
| Rosevean Properties Limited | Real estate | 2006 |
| Rosevidney Long Barn Management Limited | Households | 1996 |
| Rosevidney Properties Limited | Professional & scientific | 2006 |
| Roskilly Surveyors Ltd | Professional & scientific | 2021 |
| Rossiter House (Cornwall) Limited | Hospitality | 1989 |
| Rothwell Historical Restoration Limited | Construction | 2017 |
| Rothwell to the Point Ltd | Professional & scientific | 2018 |
| Roundhouse Penzance Ltd | Hospitality | 2022 |
| Route Education Ltd | Education | 2025 |
| Royale Court Penzance Limited | Households | 1980 |
| RS Carpentry & Construction Limited | Manufacturing | 2025 |
| RS Fitness Ltd | Health & social care | 2009 |
| Rsurg Ltd | Health & social care | 2024 |
| RTA Recovery & Garage Services Ltd | Wholesale & retail | 2015 |
| Russell Energy Consulting Limited | Professional & scientific | 2017 |
| RYN Gwari Farm - Nursery, Pre-School & Forest School CIC | Education | 2022 |
| Ryter Ltd | Information & communication | 2016 |
| S George Holdings Limited | Financial services | 2022 |
| S J Construction (South West) Limited | Construction | 2014 |
| S M Laity Holding Ltd | Financial services | 2026 |
| S M Laity Properties Ltd | Real estate | 2019 |
| S.J. & M.F. Nowell Fishing Limited | Agriculture & fishing | 2011 |
| S.J. Quick & Sons Limited | Construction | 2006 |
| Sacrola Limited | Other services | 2018 |
| Safari Research Limited | Professional & scientific | 2003 |
| Safe & Sound Removals Ltd | Transport & logistics | 2024 |
| Safe Location Services Ltd | Administrative & support | 2020 |
| Safeguard Developments Limited | Construction | 2007 |
| Safeguarding Works Limited | Education | 2016 |
| Sahara DRY UK Ltd | Wholesale & retail | 2026 |
| Salt Water Linen Hire Ltd | Other services | 2017 |
| SAM Strick Holdings Ltd | Administrative & support | 2018 |
| SAM Strick Properties Limited | Real estate | 2020 |
| Sandow's Services Limited | Construction | 1990 |
| Sandy Cove Boatyard Ltd | Manufacturing | 2020 |
| Sarah Ball Artist Limited | Arts & recreation | 2023 |
| Sarshine Limited | | 1989 |
| Savaria Medical Limited | Health & social care | 2019 |
| SC Dogs Ltd | Manufacturing | 2023 |
| Scalar Property Management Limited | Households | 1978 |
| Schools OUT Surf Ltd | Administrative & support | 2025 |
| Scilly Travel Ltd | Professional & scientific | 2020 |
| Scott Richards Golf Limited | Wholesale & retail | 2015 |
| Sea Clear Limited | Hospitality | 2018 |
| Sea Galaxy Limited | Hospitality | 2017 |
| Sea Moor Cornwall Ltd | Wholesale & retail | 2015 |
| Sea Thru Limited | Professional & scientific | 2025 |
| Seabeyond Ltd | Hospitality | 2018 |
| Seaborne Management Limited | Financial services | 2018 |
| Seafood & EAT IT Fishing Limited | Agriculture & fishing | 2016 |
| Seafood Cornwall Training Limited | Education | 2009 |
| Search Machines Ltd | Information & communication | 2019 |
| Searle & SON Ltd | Agriculture & fishing | 2016 |
| Seascape (HP) Limited | Administrative & support | 2018 |
| Seaside Sennen Ltd | Hospitality | 2024 |
| Seaswept Limited | Health & social care | 2021 |
| Seawind Ltd | Professional & scientific | 2023 |