| Newlyn Art Gallery Limited | Arts & recreation | 1977 |
| Newlyn Crab Company Ltd | Manufacturing | 2019 |
| Newlyn Filmhouse Ltd | Arts & recreation | 2013 |
| Newlyn Harbour Design Centre Limited | Manufacturing | 2009 |
| Newlyn Pharmacy Limited | Extraterritorial | 2013 |
| Newlyn Regeneration CIC | Real estate | 2023 |
| Newlyn School of Art | Arts & recreation | 2011 |
| Newon Renewables Limited | Professional & scientific | 2026 |
| NEX Creative Ltd | Professional & scientific | 2024 |
| Nicholls Properties (Cornwall) Ltd | Real estate | 2021 |
| Nick Praed Ltd | Arts & recreation | 2023 |
| Nigel Winn Building Surveyor Limited | Construction | 2017 |
| NLK Consultants Limited | Professional & scientific | 1985 |
| NO Beige Limited | Professional & scientific | 2026 |
| Noah Millard Limited | Construction | 2016 |
| Noah Werth Film & Photography Ltd | Professional & scientific | 2021 |
| Noble Palms Limited | Wholesale & retail | 2016 |
| Noble Salamander Limited | Health & social care | 2019 |
| Nocariessmile Ltd | Health & social care | 2023 |
| Noki Limited | Manufacturing | 2021 |
| Norsk Carpentry and Building Ltd | Manufacturing | 2022 |
| Nowell Construction Ltd | Construction | 2024 |
| Numinous Dance Theatre Company CIC | Arts & recreation | 2024 |
| NXT Build Ltd | Construction | 2021 |
| O C Properties Ltd | Real estate | 2021 |
| O P T (9% PZ) Ltd | Hospitality | 2010 |
| O S S Limited | Manufacturing | 1994 |
| O'Neill Safety Management Limited | Administrative & support | 2013 |
| Oakland Homes (South West) Limited | Construction | 2005 |
| Oberi Art CIC | Information & communication | 2024 |
| OFF Grid Eats Ltd | Hospitality | 2026 |
| Old Manse Management Company 1245 Ltd | Real estate | 2022 |
| One & ALL Sports Cards Ltd | Wholesale & retail | 2025 |
| One and ALL Games Limited | Arts & recreation | 2016 |
| One Health Action | Other services | 2026 |
| Open Briefing Ltd | Professional & scientific | 2011 |
| Open Doors Consultancy Ltd | Professional & scientific | 2024 |
| Optimum Property Group Ltd | Water & waste | 2018 |
| Orange Café Bar Ltd | Hospitality | 2022 |
| Orchard House (Penzance) Limited | Households | 1976 |
| Orchard Walls Flats Ltd | Real estate | 2020 |
| Ornette Spenceley Design Ltd | Construction | 2025 |
| Orofacial Surgicare Limited | Health & social care | 2016 |
| OUR Own Co. Ltd | Hospitality | 2020 |
| OUR Storylines CIC | Information & communication | 2014 |
| Output Industries Limited | Information & communication | 2022 |
| Outsourcing Manufacturing China Limited | Wholesale & retail | 1999 |
| Overmatter Limited | Information & communication | 2006 |
| P.I. Richardson Limited | Real estate | 1973 |
| P3 Project Development Limited | Professional & scientific | 2002 |
| Pagepull Limited | Professional & scientific | 2017 |
| Paladin Projects Limited | Construction | 1997 |
| Palmer Ryan Ltd | Real estate | 2018 |
| Palomax Ltd | Construction | 2024 |
| Paracruiter Limited | Administrative & support | 2023 |
| Parc an Peath Developments Limited | Construction | 2021 |
| Participate Ltd | Public administration | 2007 |
| Patwt Ltd | Administrative & support | 2026 |
| Paul Lawer Drilling Advisor Limited | Professional & scientific | 2021 |
| Paul's Bread Limited | Manufacturing | 2025 |
| Paxton Regent Limited | Construction | 2017 |
| PB Engineers Limited | Professional & scientific | 2021 |
| PD Property and Carpentry Ltd | Manufacturing | 2025 |
| Peak Fitness Penzance Limited | Arts & recreation | 2015 |
| Peak Property and Development Limited | Construction | 2021 |
| Peck Digital Ltd | Information & communication | 2026 |
| PEK Properties (SW) Ltd | Real estate | 2023 |
| Penberth Plants Ltd | Wholesale & retail | 2019 |
| Pendeen Community Heritage | Arts & recreation | 2001 |
| Pendrea Barns Management Company Limited | Households | 2020 |
| Pengelly Court Management Company Limited | Households | 2020 |
| Pengelly Event Hire Ltd | Arts & recreation | 2023 |
| Pengersick Historic & Education Trust | Administrative & support | 2011 |
| Peninsula Accountancy Ltd | Professional & scientific | 2018 |
| Peninsula Anaesthesia Limited | Education | 2006 |
| Penmarin Limited | Professional & scientific | 2015 |
| Penmet Limited | Professional & scientific | 2001 |
| Penna & Brownridge Limited | Administrative & support | 2015 |
| Penwith 4 X 4 Centre Limited | Administrative & support | 2010 |
| Penwith Community Radio Station Community Interest Company | Information & communication | 2006 |
| Penwith Inns Ltd | Hospitality | 2025 |
| Penwith Leisure Limited | Hospitality | 2007 |
| Penwith Marine Services Limited | Manufacturing | 2016 |
| Penwith Podiatry Limited | Health & social care | 2015 |
| Penwith Renault Ltd | Wholesale & retail | 2005 |
| Penwith Respite Care Limited | Hospitality | 1997 |
| Penwith Service Centre Limited | Wholesale & retail | 2009 |
| Penwith Tank & Drain Services Limited | Water & waste | 2026 |
| Penwith Woodland Burial LLP | | 2015 |
| Penzance AFC Commercial Limited | Real estate | 2020 |
| Penzance Angling Centre Ltd | Wholesale & retail | 2023 |
| Penzance Astro Limited | Arts & recreation | 2000 |
| Penzance BID | Administrative & support | 2015 |
| Penzance Brewing Co Ltd | Manufacturing | 2008 |
| Penzance Computers Workshop Limited | Professional & scientific | 2009 |
| Penzance Crash Repair Limited | Wholesale & retail | 2017 |
| Penzance Delight Ltd | Hospitality | 2025 |
| Penzance GIN Ltd | Wholesale & retail | 2018 |
| Penzance Gymnastics C.I.C. | Arts & recreation | 2012 |
| Penzance Property Ltd | Real estate | 2019 |