| Spectrum PUB Co Ltd | Hospitality | 2017 |
| Spectrum Pubs & Bars Ltd | Hospitality | 2023 |
| Spice 4 YOU Limited | Hospitality | 2015 |
| Spoce Project Management Limited | Professional & scientific | 1994 |
| Spray Applied Systems Ltd | Construction | 2016 |
| Spring D Solutions Limited | Professional & scientific | 2023 |
| Spring Media Design Ltd | Professional & scientific | 2013 |
| ST Aubyn Park Estate Management Ltd | Real estate | 2025 |
| ST James Court (Saltash) Limited | Real estate | 2024 |
| ST. Agnes Barber Shop Limited | Other services | 2014 |
| ST. Austell Barber Shop Limited | Other services | 2017 |
| ST. Johns Court (Falmouth) Management Co. Limited | Households | 1984 |
| Star Surf Camps (UK) Limited | Arts & recreation | 2014 |
| Stark Strand Garden Design Ltd | Professional & scientific | 2025 |
| Stay on Track Limited | Health & social care | 2022 |
| Steele Property Holdings Ltd | Real estate | 2021 |
| Stephens and Stephens Developers Ltd | Administrative & support | 2008 |
| Steren Finance Group Limited | Financial services | 2023 |
| Steren Property Group Limited | Real estate | 2023 |
| Steve Toyer Limited | Wholesale & retail | 2004 |
| Stobbs Developments Ltd | Construction | 2023 |
| Stones Bakery Limited | Manufacturing | 2025 |
| Storebuzz Ltd | Information & communication | 2020 |
| Stormy Petrel RUM Limited | Manufacturing | 2025 |
| Stratton Oakmont Cornwall Ltd | Financial services | 2021 |
| Stratus Books Limited | Information & communication | 2003 |
| Stratx Consulting Limited | Professional & scientific | 2024 |
| Struthall Farm Properties Ltd | Extraterritorial | 2021 |
| Studio Bang Limited | Arts & recreation | 2025 |
| Studio Kiln Limited | Professional & scientific | 2020 |
| Studio Treggiden Limited | Arts & recreation | 2015 |
| Sully's Framing Ltd | Wholesale & retail | 2008 |
| Sun & Seaside Ltd | Professional & scientific | 2019 |
| Sunshine Cafe & Yoga Limited | Arts & recreation | 2019 |
| Sureshot Brewing Company Limited | Manufacturing | 2020 |
| Sustainable Seafood Cornwall Ltd | Agriculture & fishing | 2025 |
| SW Utilities & Leak Detection Ltd | Construction | 2025 |
| Swamp Circus Trust Limited | Arts & recreation | 2008 |
| Swamp Entertainments Ltd | Arts & recreation | 2014 |
| Sweet Cowboy Blues Limited | Manufacturing | 2025 |
| Swift Estates Ltd | Real estate | 2017 |
| Swim Wild Cornwall Ltd | Education | 2021 |
| Synergy CRW Ltd | Health & social care | 2015 |
| Synergyestates Limited | Professional & scientific | 2017 |
| Synex Group Limited | Information & communication | 2023 |
| T and F Milby Limited Limited | Hospitality | 2020 |
| T H Plastering & Home Improvements Ltd | Construction | 2023 |
| Tanya Bentley Limited | Professional & scientific | 2016 |
| Tappter Limited | Information & communication | 2016 |
| Taxi Specialists Ltd | Transport & logistics | 2012 |
| Taylor Hayes Limited | Real estate | 2021 |
| Tehmina Limited | Arts & recreation | 2009 |
| TEN Foot Limited | Information & communication | 1993 |
| THE Alignment LAB Ltd | Health & social care | 2024 |
| THE ARK Nursery Limited | Education | 2016 |
| THE Atlantic Vineyard LLP | | 2022 |
| THE Aussie Smoker Ltd | Manufacturing | 2016 |
| THE Basement Padstow Limited | Hospitality | 2013 |
| THE Beak Brewery Limited | Manufacturing | 2018 |
| THE Boathouse Barking CIC | Arts & recreation | 2014 |
| THE Booth Games Ltd | Information & communication | 2026 |
| THE Brocklebank Partnership Ltd | Professional & scientific | 2016 |
| THE Cleveland Agency Ltd | Information & communication | 2016 |
| THE Colour House Limited | Administrative & support | 2015 |
| THE Courtyard Penmount Farm Management Company Limited | Households | 1987 |
| THE Crow's Nest in the Square Limited | Hospitality | 2010 |
| THE Cutty Bark Limited | Agriculture & fishing | 2026 |
| THE Devery Practice Ltd | Other services | 2014 |
| THE Dryboot Company Ltd | Wholesale & retail | 2026 |
| THE Flicka Foundation | Agriculture & fishing | 2013 |
| THE Flower Field Ltd | Agriculture & fishing | 2026 |
| THE Garden Eatery Ltd | Hospitality | 2022 |
| THE Great Berkeley Clinic Ltd | Health & social care | 1997 |
| THE Heritage Garden Kitchen Ltd | Hospitality | 2020 |
| THE Hope Guild CIC | Education | 2024 |
| THE LAB Dental Design Studio Limited | Manufacturing | 2014 |
| THE Lawrence Witts Foundation Ltd | Real estate | 2016 |
| THE Loft Cafe Coverack Limited | Hospitality | 2021 |
| THE Makerss Limited | Wholesale & retail | 2019 |
| THE Mews (Goonhavern) Management Company Limited | Households | 2022 |
| THE Mulberry Falmouth Limited | Hospitality | 2022 |
| THE Mycelial Network Ltd | Agriculture & fishing | 2024 |
| THE Oriflamme Consultancy Ltd | Construction | 2021 |
| THE Pier Bakery Ltd | Hospitality | 2021 |
| THE PR Department Limited | Professional & scientific | 1995 |
| THE Self Health Centre Cornwall Limited | Hospitality | 2025 |
| THE Stone Room at 93 Limited | Wholesale & retail | 2015 |
| THE TV and Video Repair Shop Limited | Other services | 2004 |
| THE Virtual Hippo Ltd | Health & social care | 2021 |
| THE Wentworth Catering Company Ltd | Hospitality | 2021 |
| Themensroom Limited | Other services | 2016 |
| Thessalian Ltd | Manufacturing | 2018 |
| Thevalari Ltd | Wholesale & retail | 2021 |
| Third Quarter Studio Limited | Professional & scientific | 2024 |
| Thirsty Scholar Ltd | Hospitality | 2011 |
| This Way UP Studios Ltd | Information & communication | 2025 |
| Thompson Graphic Design Ltd | Professional & scientific | 2021 |
| Thwaites Marine Ltd | Wholesale & retail | 2020 |
| Tidelight Ltd | Manufacturing | 2023 |
| Tiny Home Retreats Limited | Hospitality | 2022 |