| Northern Stores Ltd. | Wholesale & retail | 1972 |
| Northern Trading (Cumbria) Limited | Water & waste | 2008 |
| Northern Wood Fuel Ltd | Wholesale & retail | 2024 |
| Northwest Building and Aggregate Supplies Ltd | Wholesale & retail | 2024 |
| Notlad Farm Limited | Agriculture & fishing | 2021 |
| Nowak Enterprises Ltd | Professional & scientific | 2026 |
| NS Electrical (Wigton) Limited | Construction | 2020 |
| NSA Adventure & Travel Services Ltd | Administrative & support | 2021 |
| NT Precision Limited | Wholesale & retail | 1999 |
| NTS (Europe) Limited | Wholesale & retail | 1999 |
| Nuuv Ltd | Manufacturing | 2023 |
| O'Farrell Property Limited | Real estate | 2025 |
| O'Malley Plant Hire Limited | Construction | 2005 |
| Oak Close Winskill Limited | Households | 2017 |
| Oakfield Park (Kirkby Lonsdale) LLP | | 2021 |
| Oakfield Property Limited | Real estate | 2024 |
| Oakk Limited | Households | 2011 |
| Oaklands Country Park Ltd | Hospitality | 2015 |
| Oakshaw Developments Limited | Construction | 2020 |
| Obsidian Limited | Professional & scientific | 2000 |
| Occmed Ltd | Health & social care | 2008 |
| OFF Grid Agricultural Ltd | Agriculture & fishing | 2022 |
| Offramp Marketing Services Limited | Professional & scientific | 1994 |
| OFI Contracts Limited | Construction | 2024 |
| Old Line Engineering Ltd | Manufacturing | 2026 |
| Olive Tree Wellness Ltd | Other services | 2021 |
| Oliver Turvey International Limited | Arts & recreation | 2015 |
| Oliver Turvey Motorsport Limited | Arts & recreation | 2013 |
| Olson Property Ltd | Real estate | 2025 |
| Omnia Services (Penrith) Limited | Construction | 2016 |
| ON Track Safe Solutions Ltd | Construction | 2023 |
| One Little Bird Public Relations Ltd | Professional & scientific | 2013 |
| Onesport (UK) Limited | Manufacturing | 2012 |
| Onyx Coaching & Classes Ltd | Arts & recreation | 2022 |
| Opal Lounge Hair & Beauty Ltd | Other services | 2015 |
| Opco 3WT Limited | Professional & scientific | 2026 |
| Open Road Media Ltd | Arts & recreation | 2024 |
| Operation Excellence Ltd | Professional & scientific | 2024 |
| Optimum Fire & Interiors Ltd | Construction | 2014 |
| Oral Brite Dental Ltd | Health & social care | 2013 |
| Orchard Apartments (Monks Close) Ltd | Households | 2004 |
| Orchard Hideaways Limited | Hospitality | 2017 |
| Origin (Topco) Limited | Construction | 2021 |
| Original Tents and Events Limited | Administrative & support | 2017 |
| Orton Fells Farmer Cluster CIC | Administrative & support | 2021 |
| Orwin & Ball Limited | Professional & scientific | 2011 |
| Osborne and Grosvenor Properties Limited | Real estate | 2017 |
| Osborne Consulting Services (UK) Limited | Professional & scientific | 2026 |
| Ousby Management Company Limited | Households | 2004 |
| OUT of the Blue Hydro Limited | Energy | 2014 |
| Outward Bound Corporate Limited | Education | 1994 |
| Outward Bound Global | Professional & scientific | 1946 |
| P & H Plant Hire Ltd. | Construction | 1996 |
| P Squared Properties and Rentals Ltd | Real estate | 2025 |
| P&R Rowlands Property Ltd | Real estate | 2017 |
| P-Squared Real Estate Ltd | Real estate | 2023 |
| P-Squared Renovations Ltd | Construction | 2023 |
| P.Berry Group Ltd | Agriculture & fishing | 2026 |
| P.C.M. Technologies Limited | Information & communication | 1991 |
| Pacey Green Holdings Limited | Financial services | 2021 |
| Paddock Close (Penruddock) Limited | Real estate | 2024 |
| Paddy LOT Limited | Wholesale & retail | 2025 |
| Paddys Pads Limited | Real estate | 2020 |
| Pallisterco Limited | Financial services | 2006 |
| Palmer Property Services (PPS) Limited | Real estate | 2025 |
| PAN Systems Limited | Information & communication | 2003 |
| Papertex Limited | Wholesale & retail | 2002 |
| Park Farm Plant Services Ltd | Other services | 2007 |
| Parker and Charters Enterprise Limited | Hospitality | 2023 |
| Parry Contracting Ltd | Construction | 2021 |
| Parveen P Ltd | Health & social care | 2021 |
| Pastoro Group Holdings Ltd | Financial services | 2025 |
| Pastoro Properties Ltd | Real estate | 2025 |
| Pastoro Trading Ltd | Wholesale & retail | 2022 |
| Path - North Lakes Ltd | Other services | 2021 |
| Patient Memoirs Limited | Health & social care | 2009 |
| Patterdale Mountain Rescue Association Limited | Other services | 1996 |
| Paul Birkett Construction Services Ltd | Construction | 2023 |
| Paul Fleming Joinery Limited | Manufacturing | 2021 |
| Paul Scaife Associates Limited | Professional & scientific | 2013 |
| Paul Wilson Haulage Limited | Transport & logistics | 2015 |
| Pbreigneth Limited | Administrative & support | 2025 |
| PDP Associates Limited | Professional & scientific | 2010 |
| Pearl & Poesy Ltd | Wholesale & retail | 2018 |
| Pearoe Limited | Information & communication | 2019 |
| Pecfins Limited | Arts & recreation | 2015 |
| Pengen AD Limited | Energy | 2015 |
| Pengen Limited | Energy | 2014 |
| Penhorwood Creative Limited | Information & communication | 2018 |
| Pennine View (Calthwaite) Limited | Construction | 2021 |
| Pennine Window Cleaning Limited | Administrative & support | 2010 |
| Pennygate Property Limited | Real estate | 2021 |
| Penrith & District Farmers' Mart LLP | | 2002 |
| Penrith & District GUN Club Limited | Arts & recreation | 2004 |
| Penrith 40 Management Services Limited | Real estate | 2007 |
| Penrith AFC Limited | Arts & recreation | 2012 |
| Penrith BID Company Limited | Other services | 2018 |
| Penrith Body Repairs Limited | Wholesale & retail | 2025 |
| Penrith Cleaning Services Ltd | Administrative & support | 2022 |
| Penrith Commercials Ltd | Administrative & support | 2020 |