| Suhrad Global Ltd | Wholesale & retail | 2025 |
| Super Mega Action Plus Limited | Information & communication | 2007 |
| Superclean Cleaning Services SW Ltd | Administrative & support | 2022 |
| Suprima Solutions Limited | Professional & scientific | 2013 |
| Sw&Dh Investments Ltd | Professional & scientific | 2021 |
| Swatcheditor Ltd | Information & communication | 2021 |
| Swjj Ltd | Construction | 2018 |
| Sycamore Solutions (UK) Limited | Professional & scientific | 2009 |
| Synergy DB Limited | Construction | 2017 |
| T.W. Colley & Sons Limited | Wholesale & retail | 1936 |
| Tallis Engineering and Consulting Services Limited | Professional & scientific | 2013 |
| Tanyard Youth Project Limited | Other services | 2005 |
| Tasdemir Limited | Hospitality | 2012 |
| Tedbern Developments Limited | Construction | 2021 |
| THE Academy of Beauty Pembrokeshire Limited | Other services | 2021 |
| THE Beach House Oxwich Ltd | Hospitality | 2016 |
| THE Brewery Inn Cosheston Ltd | Hospitality | 2015 |
| THE Collaboration Laboratory Ltd | Administrative & support | 2019 |
| THE Cooks Cupboard Ltd | Wholesale & retail | 2011 |
| THE Crazy Dragon T-Shirt Company Ltd | Wholesale & retail | 2025 |
| THE Globe Hotel Angle Ltd | Hospitality | 2015 |
| THE Grove Narberth Ltd | Hospitality | 2015 |
| THE Haven Church Pembroke | Other services | 2004 |
| THE HR Co Pembrokeshire Ltd | Administrative & support | 2026 |
| THE Salty Spaniel Ltd | Wholesale & retail | 2023 |
| THE Seren Collection Limited | Hospitality | 2017 |
| THE SKN Studio Ltd | Other services | 2024 |
| THE Tiddlywink Mobile Bar Ltd | Hospitality | 2020 |
| Thme Limited | Extraterritorial | 2017 |
| Thomas Group Limited | Administrative & support | 2023 |
| Thorpesend Management Limited | Households | 1989 |
| Tidal Design Limited | Professional & scientific | 2020 |
| TL Stevens Ltd | Other services | 2023 |
| TOM Inns Ltd | Hospitality | 2013 |
| Top Taverns Ltd | Hospitality | 2015 |
| Topp Tyres Limited | Wholesale & retail | 2017 |
| Tork Health Communications Limited | Health & social care | 2004 |
| Touch of Care Ltd | Health & social care | 2022 |
| Tracslip Ltd | Manufacturing | 2026 |
| Trans Properties Limited | | 2023 |
| Trans Securities Limited | | 2023 |
| Tree & Landscapes Ltd | Administrative & support | 2026 |
| Trewent Property Services Ltd | Construction | 2022 |
| True Ltd | Other services | 2020 |
| Truxor UK Ltd. | Wholesale & retail | 2018 |
| Tuff N’ Tumble Ltd | Health & social care | 2026 |
| USA Diners Ltd | Hospitality | 2026 |
| Vale & Valley Tree & Garden Services Ltd | Administrative & support | 2026 |
| W G Richards & Sons Ltd | Agriculture & fishing | 2002 |
| Water and Cook Ltd | Wholesale & retail | 2025 |
| Waterloo House Games and Coffee Ltd | Hospitality | 2025 |
| WBL2 Building Supplies Ltd | Wholesale & retail | 2020 |
| Weald Court Limited | | 2022 |
| Webtree Limited | Information & communication | 2007 |
| West Coast Taxis Ltd | Transport & logistics | 2024 |
| West Wales Chiropractic Ltd | Health & social care | 2014 |
| West Wales Hoof Care Ltd | Professional & scientific | 2019 |
| Wevvy Aviation Limited | Transport & logistics | 2023 |
| Wheelers (Old Kings Arms Hotel) Limited | Hospitality | 1975 |
| Wild West Escapes CYF | Hospitality | 2023 |
| WK Inspection Services Ltd | Manufacturing | 2015 |
| Woodenbale 2000 Limited | Construction | 1998 |
| Woodfield (Pembs) Limited | Transport & logistics | 2015 |
| Yakkida Ltd | Wholesale & retail | 2022 |
| ZN Café Ltd | Hospitality | 2022 |