| Pureroom UK Limited | Wholesale & retail | 2015 |
| Q Tanning Ltd | Other services | 2023 |
| Quality Homes Pembroke Ltd | Construction | 2023 |
| R&S Waste Solutions Ltd | Water & waste | 2023 |
| Rae's Toys Ltd | Manufacturing | 2025 |
| Raven Technologies Ltd | Manufacturing | 2021 |
| Red River Creative Limited | Wholesale & retail | 2007 |
| Redkey Construction Limited | Construction | 2015 |
| Redstone Property Group Ltd | Real estate | 2026 |
| Rees Architectural Services Limited | Professional & scientific | 2020 |
| REH Limited | Professional & scientific | 2005 |
| REH Works Limited | Construction | 2024 |
| Rekaso Salon Ltd | Other services | 2024 |
| Renovation Dreams Ltd | Construction | 2026 |
| Richard Perrett Watchmaker Limited | Manufacturing | 2020 |
| Right Price Scaffolding Limited | Construction | 2025 |
| Rmdm Properties Ltd | Real estate | 2025 |
| Robinson Retail Limited | Wholesale & retail | 2002 |
| Role Model Group Limited | Manufacturing | 2024 |
| RSG Energy Limited | Construction | 2015 |
| S & P Management and Maintenance Ltd | Professional & scientific | 2018 |
| S P Promotional Services Limited | Information & communication | 1988 |
| Salon Q Ltd | Other services | 2023 |
| SB Total Telecommunications Ltd | Administrative & support | 2017 |
| Seadog Productions Ltd | Information & communication | 2012 |
| Secure Rooms Ltd | Real estate | 2020 |
| Seven Spice Pembroke Dock Limited | Hospitality | 2019 |
| Sickleholme Services Limited | Wholesale & retail | 1987 |
| Similan Diving Tours Ltd | Administrative & support | 2019 |
| Simply Group Holdings Ltd | Financial services | 2023 |
| Simply Landscaping Pembrokeshire Ltd | Administrative & support | 2019 |
| Simply Lettings Pembrokeshire Ltd | Real estate | 2025 |
| Simply Sheds Ltd | Manufacturing | 2023 |
| SK M & C Ltd | Professional & scientific | 2024 |
| Slade Cross Ltd | Real estate | 2021 |
| SM Bespoke Care Ltd | Health & social care | 2024 |
| South Pembrokeshire Golf Club Limited | Arts & recreation | 1994 |
| South Wales Autograss League Limited | Arts & recreation | 2003 |
| Stormborn Games CIC | Hospitality | 2025 |
| Strangefish Limited | Professional & scientific | 2013 |
| Styromelt Limited | Professional & scientific | 2007 |
| Summer Garden 888 Ltd | Hospitality | 2022 |
| Sunset West Limited | Extraterritorial | 2009 |
| Sureline Design Services Ltd | Professional & scientific | 2007 |
| Swift Spray Ltd | Construction | 2025 |
| Symbiosis Dental Practice LLP | | 2011 |
| Syncro Motor Factors Ltd | Wholesale & retail | 2007 |
| Synergy Health, Wellness & Fitness Education Centre Ltd | Health & social care | 2012 |
| T.L.Bowling & SON Limited | Wholesale & retail | 1960 |
| Talyfan Properties Limited | Real estate | 1996 |
| Techno Engineering Limited | Manufacturing | 1986 |
| THE Alma Inn (Pembrokeshire) Limited | Hospitality | 2005 |
| THE Butlers Consulting Ltd | Professional & scientific | 2024 |
| THE Cricketers Lodge Ltd | Hospitality | 2016 |
| THE Leaflet Effect Limited | Administrative & support | 2024 |
| THE Northgate Ltd | Hospitality | 2026 |
| THE Old Navy Apartments Limited | Real estate | 2007 |
| THE Pater Hall Community Trust | Arts & recreation | 2004 |
| THE Pembroke Dock Heritage Trust Limited | Arts & recreation | 2006 |
| THE Purple Lily Group Ltd | Financial services | 2026 |
| THE Therapy Rooms Pembrokeshire Ltd | Health & social care | 2016 |
| Thepowersite Limited | Wholesale & retail | 2012 |
| This Way UP Project CIC | Wholesale & retail | 2025 |
| Tidal Technologies W1 Ltd | Manufacturing | 2025 |
| Time Flies Pembs Limited | Wholesale & retail | 2015 |
| TMT-02 Limited | Hospitality | 2023 |
| Total Generation Limited | Professional & scientific | 2016 |
| Totally Floor'D Ltd | Manufacturing | 2022 |
| Treadstone Estates Limited | Real estate | 2016 |
| Tredegar Chambers Limited | Real estate | 2023 |
| Trew's Cleaning Management Limited | Administrative & support | 2018 |
| Trinity Education Limited | Education | 2020 |
| TW Investors Group UK Limited | Manufacturing | 2025 |
| Tweet Street Ltd | Real estate | 2020 |
| TŶ Syml Ltd | Professional & scientific | 2019 |
| Ubba Ltd | Arts & recreation | 2019 |
| UK EV Charger Ltd | Construction | 2022 |
| UK Paragliding Limited | Extraterritorial | 2023 |
| UK Spray Rendering Ltd | Administrative & support | 2018 |
| Upton Castle Events Ltd | Hospitality | 2025 |
| Upton Farm Frozen Foods Limited | Wholesale & retail | 1986 |
| Valcore Solutions Ltd | Information & communication | 2025 |
| Vehogroup Ltd | Information & communication | 2012 |
| Ventana Properties Ltd | Households | 2020 |
| Victoria Road Limited | Professional & scientific | 2003 |
| Video Screen Services Limited | Arts & recreation | 2018 |
| Visit Pembrokeshire | Other services | 2001 |
| Vortech Records Limited | Arts & recreation | 2024 |
| Voyager Gear Limited | Administrative & support | 2025 |
| Walwyn-Phillips Investments Ltd | Real estate | 2025 |
| Wavecrest Cafe Limited | Hospitality | 2013 |
| West Pennar Properties Limited | Real estate | 2018 |
| West Street Living Ltd | Real estate | 2023 |
| West Wales Maritime Heritage | Arts & recreation | 1991 |
| West Wales Parking Limited | Administrative & support | 2024 |
| West Wales Waste Limited | Water & waste | 2018 |
| Western Services Limited | Construction | 2019 |
| Westival Limited | Arts & recreation | 2018 |
| Westside Fitness Ltd | Arts & recreation | 2020 |
| Westside Lettings Limited | Real estate | 2025 |