| Sealock Properties LLP | | 2016 |
| Sean Clancy Entertainment Limited | Arts & recreation | 2024 |
| Sean Mcgoldrick Inspection Services Ltd | Professional & scientific | 2024 |
| Sedisathedop Ltd | Professional & scientific | 2025 |
| Seedhill Convenience Store Ltd | Wholesale & retail | 2011 |
| Seedhill Express Ltd | Wholesale & retail | 2021 |
| Seedhill Group Ltd | Financial services | 2024 |
| Seedhill Superstore Ltd | Wholesale & retail | 2016 |
| Sefa Trading Ltd | Wholesale & retail | 2026 |
| Sehguh Limited | Professional & scientific | 2007 |
| Sellarectrics Ltd | Construction | 2023 |
| Selloco Limited | Financial services | 2025 |
| Senga’S Cafe Ltd | Hospitality | 2019 |
| Senna Garage Services Limited | Wholesale & retail | 2021 |
| Sentinel Capital Advisors Ltd | Real estate | 2024 |
| Sentinel Sovereign FIC Ltd | Professional & scientific | 2025 |
| Seo's | | 2005 |
| Serendipity West Ltd | Hospitality | 2023 |
| Serene Clean Homes LLP | | 2026 |
| Serene Clean Renfrewshire Ltd | Administrative & support | 2025 |
| Seveniv Ltd | Wholesale & retail | 2025 |
| SEYDAM27 Limited | Hospitality | 2026 |
| SF Admin Ltd | Administrative & support | 2021 |
| SG Laser Aesthetics Ltd | Other services | 2024 |
| Shadow Beauty Perth Ltd | Other services | 2016 |
| Shah Traders Paisley Ltd | Wholesale & retail | 2023 |
| Shaikh Faisal Ltd | Information & communication | 2012 |
| Shakehaus Limited | Information & communication | 2016 |
| Shan-Vic Properties Ltd | Financial services | 2025 |
| Shannon Joinery Services Ltd | Construction | 2016 |
| Shardot Ltd | Other services | 2014 |
| Sharif Bros. (Glasgow) Limited | Professional & scientific | 1984 |
| Sharm 5 Ltd | Wholesale & retail | 2021 |
| Sharon Collins Solicitors Ltd | Professional & scientific | 2024 |
| Shave of the Day Ltd | Other services | 2025 |
| Shawarma Sherwood Ltd | Hospitality | 2026 |
| Shawhill Gray Ltd | Health & social care | 2024 |
| Shayor Ventures Ltd | Health & social care | 2023 |
| Shearer Horseshoeing Limited | Agriculture & fishing | 2010 |
| Sheenro UK Limited | Financial services | 2016 |
| Sheeran IT Services Limited | Information & communication | 2011 |
| Sheona Hosie Hair Design Limited | Other services | 2013 |
| Sheridan Legal Services Ltd | Professional & scientific | 2025 |
| Sherlock Academy Ltd | Other services | 2025 |
| Sherlock Mortgages and Protection Ltd | Financial services | 2023 |
| Sherlocks Brownstone Ltd | Administrative & support | 2015 |
| Shieldhall Logistics Limited | Transport & logistics | 2009 |
| Shift UP Driving Academy Ltd | Education | 2025 |
| Shiftpoint IT Consulting Ltd | Information & communication | 2025 |
| Shine & Spark Ltd | Administrative & support | 2025 |
| Shine Home Improvements Ltd | Construction | 2024 |
| Shine Window & Doors Ltd | Manufacturing | 2024 |
| Shiptech (UK) Limited | Administrative & support | 1989 |
| Shiptech Limited | Administrative & support | 1975 |
| Shireway Joinery Ltd. | | 2007 |
| Shjm Ltd | Hospitality | 2025 |
| Shoaib.K Optical Ltd | Health & social care | 2025 |
| Shock City Europe Limited | Information & communication | 2017 |
| Shock City Productions Limited | Arts & recreation | 2014 |
| Shopierx Ltd | Wholesale & retail | 2026 |
| Shopmobility Renfrewshire | Other services | 2002 |
| Shreya Restaurants Ltd | Hospitality | 2025 |
| SID Management Limited | Administrative & support | 2016 |
| Sidak Shah JI Retail Ltd | Wholesale & retail | 2021 |
| Sieef Developements Ltd | Construction | 2025 |
| Signal Fire & Security Ltd | Construction | 2024 |
| Signature Heating & Plumbing Ltd | Construction | 2021 |
| Signature Moves Ltd | Transport & logistics | 2023 |
| Signature Skin Clinic Ltd | Other services | 2018 |
| Signature Tiling Ltd | Construction | 2015 |
| Signature Wall & Floor Tiling Ltd | Construction | 2020 |
| Signs Direct Scotland Limited | Manufacturing | 2013 |
| Silver Lining Cleaning Services Limited | Administrative & support | 2026 |
| Simple Funerals (Scotland) Ltd | Extraterritorial | 2021 |
| Simpson Reporting Services Ltd | Health & social care | 2014 |
| Simpson's Joinery & Upholstery Limited | Other services | 2020 |
| Sinclair Logistics Limited | Transport & logistics | 2009 |
| Sintech Projects Ltd | Professional & scientific | 2023 |
| SIR Properties (Scotland) Limited | Real estate | 2023 |
| Sittas Auto Exports Ltd | Wholesale & retail | 2024 |
| Size Enterprises Ltd | Administrative & support | 2025 |
| Sizzler 786 Ltd | Hospitality | 2023 |
| SJ Auto Motors Limited | Wholesale & retail | 2019 |
| SJB Debt Help Ltd | Professional & scientific | 2025 |
| SJB Group Ltd | Construction | 2018 |
| SJH International Limited | Professional & scientific | 2009 |
| SJH Property Investment SPV1 Limited | Real estate | 2018 |
| Sjlk Ltd. | Wholesale & retail | 2012 |
| SJV Construction Ltd | Construction | 2023 |
| SK & H Trading Ltd | Wholesale & retail | 2013 |
| SK Dimond Ltd | Administrative & support | 2025 |
| SK Global Solution Ltd | Transport & logistics | 2025 |
| Skanderbeg Motors Ltd | Wholesale & retail | 2021 |
| Skills Training Group Ltd | Education | 2018 |
| Skin Revive Medical Aesthetics Ltd | Other services | 2024 |
| Skin-Fresh (Scotland) Ltd | Other services | 2025 |
| Skirlies Cafe Limited | Hospitality | 2018 |
| Skirlies Catering Limited | Hospitality | 2018 |
| Skivvies Limited | Administrative & support | 2019 |
| SKM Property Management Limited | Real estate | 2018 |