| DRÉ Garcia Ltd | Wholesale & retail | 2025 |
| DSK Construct Ltd | Construction | 2023 |
| Dunard Management Company Limited | Households | 2005 |
| Dunstone Court Management Limited | Households | 1989 |
| Duodot Ltd | Professional & scientific | 2025 |
| Durafil Developments Ltd | Construction | 2025 |
| DW Complex Care Ltd | Health & social care | 2019 |
| DW Housing Solutions Ltd | Real estate | 2025 |
| Dynamic Entertainments Agency Ltd | Arts & recreation | 2023 |
| Dynamic Harmony Ltd | Professional & scientific | 2024 |
| Dynamixx Ltd | Construction | 2024 |
| Dzna Limited | Real estate | 2024 |
| Eales Electrical Contractors Ltd | Construction | 2018 |
| Earth Waste Management Limited | Water & waste | 2019 |
| East Devon Fhah Ltd | Other services | 2022 |
| East River Design Limited | Professional & scientific | 2025 |
| East Street Property Company Ltd | Real estate | 2023 |
| East Street PUB Company Ltd | Hospitality | 2014 |
| Eco Accounting Limited | Professional & scientific | 2017 |
| Eco Trades Renewables Ltd | Extraterritorial | 2013 |
| Eco Trades South West Ltd | Construction | 2012 |
| Ecoloco Ltd | Construction | 2017 |
| Eddie Bent Associates Limited | Professional & scientific | 2015 |
| Edentide Ltd | Construction | 2021 |
| Edginswell Drive Freehold Ltd | Real estate | 2020 |
| Edginswell Gardens Ltd | Construction | 2013 |
| Edwards Construction (SW) Limited | Construction | 2026 |
| EJ Elston Limited | Professional & scientific | 2003 |
| Ej's Sports Bar Ltd | Hospitality | 2020 |
| Elite Hospitality Solutions Limited | Wholesale & retail | 2026 |
| Elite Smart Business Solutions Limited | Administrative & support | 2025 |
| Elite Window Cleaners Torbay Ltd | Administrative & support | 2026 |
| ELL & MAR Civil Engineering Ltd | Construction | 2022 |
| Ellis Building LLP | | 2026 |
| Ellis-Ridings Mortgage Solutions Ltd | Financial services | 2023 |
| Elsey Masonry Work Ltd | Construction | 2026 |
| Eltec Systems Ltd | Professional & scientific | 2017 |
| Emmily Sorelle Ltd | Information & communication | 2024 |
| English Riviera Bike Night C.I.C. | Other services | 2024 |
| Enigma Design and Signs Limited | Professional & scientific | 2022 |
| Enlifo Ltd | Information & communication | 2020 |
| Enya and Margo Ltd | Wholesale & retail | 2022 |
| Equalown Property Management Limited | Households | 1993 |
| Equalterm Property Management Limited | Households | 1987 |
| Equity Release South West Ltd | Financial services | 2017 |
| Eric Lloyd & Co (Churston) Ltd | Real estate | 1995 |
| Eroarteurope Ltd | Administrative & support | 2019 |
| ES Paradise Ltd | Manufacturing | 2023 |
| Estadio Tech Ltd | Information & communication | 2026 |
| ET Cetera Limited | Real estate | 2024 |
| Eternal Sparks Ltd | Extraterritorial | 2024 |
| ETF Project Management Limited | Construction | 2025 |
| EU Translations (UK) Ltd | Administrative & support | 2014 |
| Euras Technology (UK) Ltd | Construction | 2023 |
| EV Complete Ltd | Construction | 2019 |
| Evans Tree Care Ltd | Agriculture & fishing | 2025 |
| Everyday Communities CIC | Education | 2022 |
| Exercise in Care Ltd | Other services | 2023 |
| Exeter Support Ltd | Other services | 2024 |
| Exjet Services Ltd | Construction | 2023 |
| Explorer IP Ltd | Wholesale & retail | 2025 |
| Expression (Pinhoe) Apartments Management Company Limited | Households | 2017 |
| Extreme Bike Battle Ltd | Arts & recreation | 2020 |
| Ezisan Ltd | Manufacturing | 2021 |
| F L Construction Ltd | Construction | 2010 |
| F&E Group Ltd | Construction | 2024 |
| Fabulash (South West) Limited | Other services | 2017 |
| Farm and Fencing Supplies Ltd | Wholesale & retail | 2026 |
| Farthing Place Management Company Limited | Households | 2003 |
| Fast Driving Test Booking Ltd | Education | 2022 |
| FAT Belly Cards Ltd | Wholesale & retail | 2025 |
| Fdtbooking Ltd | Education | 2024 |
| Feed South Devon CIC | Hospitality | 2020 |
| Fenestrauk Limited | Construction | 2024 |
| Fhah Services Ltd | Other services | 2020 |
| Final Wishes Ltd | Professional & scientific | 2025 |
| Finance 4 Everything Limited | Financial services | 2025 |
| FIO Domus Ltd | Construction | 2013 |
| Fire Risk Assessors South West Ltd | Financial services | 2024 |
| Firebug Torbay CIC | Manufacturing | 2024 |
| First Form Electrical Ltd | Construction | 2024 |
| First Interiors (Torbay) Limited | Wholesale & retail | 1993 |
| First Interiors Bathrooms Ltd | Wholesale & retail | 2019 |
| Firstfix Electrical Services Ltd | Construction | 2016 |
| Fiteo Limited | Wholesale & retail | 2015 |
| Five Star Nails Paignton Ltd | Other services | 2026 |
| Flexiguide Limited | Manufacturing | 2002 |
| FLH Connect Ltd | Transport & logistics | 2026 |
| Florence Edward Ltd | Health & social care | 2023 |
| FLR Services Limited | Information & communication | 2003 |
| FMN Gardens Ltd | Administrative & support | 2015 |
| Focus Hospitality Limited | Hospitality | 2012 |
| Foremost Packaging Ltd | Manufacturing | 1989 |
| Foreshore House (Budleigh Salterton) Management Company Limited | Households | 1975 |
| Forest Ridge Building Company Limited | Construction | 2000 |
| Fortitude First AID Ltd | Education | 2022 |
| Fougou Ltd | Arts & recreation | 2008 |
| Fougou Media Ltd | Arts & recreation | 2008 |
| Fougou Music Ltd | Arts & recreation | 2012 |
| Fox's Hot Property Ltd | Real estate | 2024 |