| Rperini Cleaning Services Limited | Administrative & support | 2025 |
| RS Defence Legal Ltd | Administrative & support | 2022 |
| Rubisko Limited | Information & communication | 2023 |
| Runa Spice Limited | Hospitality | 2024 |
| RVB Business Services Limited | Administrative & support | 2014 |
| RVL New Homes Ltd | Real estate | 2021 |
| RWA Advisory Limited | Professional & scientific | 2020 |
| S & P House Ltd | Real estate | 2025 |
| S. M. GAS Services Ltd | Construction | 2007 |
| Sachi Reese Ltd | Professional & scientific | 2023 |
| Saddlecombe Stud Limited | Agriculture & fishing | 2016 |
| Sage Content Studio Limited | Real estate | 2025 |
| Sally Clarke (Westbourne Grove) Limited | Wholesale & retail | 2020 |
| Saltmine Ventures Ltd | Information & communication | 2012 |
| Salvatore Schifano Consulting Limited | Professional & scientific | 2020 |
| Samoda Ltd | Wholesale & retail | 2024 |
| Samson CC Ltd | Construction | 2011 |
| Sanctum Pathways Ltd | Public administration | 2025 |
| Sanctum Recruitment Ltd | Other services | 2016 |
| Sandrock Estates Limited | Real estate | 1997 |
| Sandstones Europe Ltd. | Professional & scientific | 2001 |
| Sandstones Limited | Professional & scientific | 2002 |
| Sandy Management Company Limited | Households | 1987 |
| Sarah Marsh Ltd | Wholesale & retail | 2005 |
| Sarah Taylor Consulting Ltd | Professional & scientific | 2015 |
| Sarwar Oncology Limited | Health & social care | 2015 |
| Satsuki Aesthetics Ltd | Other services | 2024 |
| Sauze Stayz Ltd | Hospitality | 2016 |
| Savon Rose Ltd | Wholesale & retail | 2020 |
| SBS Print Ltd | Manufacturing | 2022 |
| Scarletts Training Limited | Professional & scientific | 2007 |
| Scent Direct International Limited | Wholesale & retail | 1999 |
| School Match UK Limited | Education | 2025 |
| School of Choice UK Ltd | Education | 2025 |
| Scott M Williams Ltd | Information & communication | 2014 |
| Scott Taylor Garden Design Limited | Professional & scientific | 2018 |
| Seafort Investments Limited | Financial services | 2022 |
| Seafort Maritime Limited | Administrative & support | 2020 |
| Seal Business Development Limited | Administrative & support | 2016 |
| Sealion Property Management Limited | Transport & logistics | 1999 |
| Seebaruk Media Ltd | Information & communication | 2018 |
| Select Auto Systems Limited | Wholesale & retail | 2008 |
| Select Commercial Plumbing & Heating Ltd | Construction | 2012 |
| Selected Interventions Limited | Information & communication | 2011 |
| Sellahezra Limited | Professional & scientific | 1967 |
| Selles Consulting Ltd | Professional & scientific | 2022 |
| Semc Investments Limited | Real estate | 2021 |
| Sensible PC Solutions Limited | Information & communication | 2006 |
| Sensible Solutions (South East) Limited | Information & communication | 2006 |
| Serma Construction Limited | Construction | 2019 |
| Seven Sense Management Limited | Professional & scientific | 2023 |
| Sevenoaks Garden Buildings Limited | Construction | 2024 |
| Shael Investments Limited | Financial services | 2023 |
| Shared Understanding Ltd | Information & communication | 2026 |
| Sharper Image Films Limited | Administrative & support | 2011 |
| Shaws (EAL) Limited | Real estate | 2000 |
| Shepherd Publishing Limited | Information & communication | 1996 |
| Shepperton Green Limited | Real estate | 2001 |
| Sherwoods International Properties Limited | Administrative & support | 2007 |
| Sheryl's Art Deco Limited | Wholesale & retail | 2012 |
| Shortle Marketing Limited | Professional & scientific | 2013 |
| Sicoca Ltd | Construction | 2025 |
| Silkham Properties Ltd | Real estate | 2022 |
| Simon Brand Consulting Limited | Information & communication | 1997 |
| Simon P. Wood Limited | Construction | 2004 |
| Simon R Fowler Ltd | Construction | 2010 |
| Simworld Limited | Extraterritorial | 1998 |
| Singleton Close (Management) Limited | Households | 1986 |
| Sipson Green Limited | Real estate | 2001 |
| Siquenco Investments Ltd | Real estate | 2014 |
| SIX4 Group Ltd | Professional & scientific | 2023 |
| Sj&A Property Co Limited | Real estate | 2025 |
| SJG HR Consultancy Limited | Professional & scientific | 2025 |
| SJR Integrity Services Ltd | Professional & scientific | 2023 |
| Skin RX Surrey Limited | Health & social care | 2023 |
| Skunk Works 2025 Ltd | Information & communication | 2025 |
| Skyglass Developments Limited | Construction | 2013 |
| Skyline Cafe Ltd | Hospitality | 2023 |
| Skyra Ltd | Professional & scientific | 2018 |
| SL & RT Ltd | Households | 2023 |
| SLB Carpentry & Build Ltd | Construction | 2017 |
| SLB One Limited | Financial services | 2022 |
| Small Spaces Ltd | Construction | 2021 |
| Smarana Sanctuary Ltd | Professional & scientific | 2021 |
| Smart Accounting & Tax Solutions LLP | | 2011 |
| Smart Corporate Finance Solutions Ltd | Professional & scientific | 2017 |
| Smart Systems Consulting Ltd. | Professional & scientific | 2013 |
| Smartseal Flat Roofing Limited | Construction | 2006 |
| Smet Staircases Limited | Construction | 2012 |
| Smet UK Limited | Construction | 2006 |
| Smith & Stone Consultancy Limited | Administrative & support | 2017 |
| Smith & Stone Printing Ltd | Administrative & support | 2017 |
| Smith Square Finance Company Limited | Real estate | 1977 |
| Smith’S Seasonal Boxes Ltd | Wholesale & retail | 2025 |
| SO Handy Ltd | Construction | 2019 |
| SO Property Ltd | Other services | 2011 |
| SO Select Limited | Administrative & support | 2017 |
| Soho Media Finance Limited | Financial services | 2018 |
| Solar Near ME Limited | Information & communication | 2023 |
| Solv-It Services Limited | Information & communication | 2015 |