| Lader Systems Limited | Other services | 2004 |
| Lady Margaret Hall Trading Limited | Construction | 1994 |
| Lady Place Management Company Limited | Households | 1999 |
| Ladybird Homes Limited | Real estate | 2017 |
| Lafresh Ltd | Health & social care | 2022 |
| Laila Qume Ltd | Real estate | 2021 |
| Lal's Deli Ltd | Hospitality | 2015 |
| Lalueur Pro Ltd | Other services | 2024 |
| Lama Taxi Services Ltd | Transport & logistics | 2025 |
| Lamarsh Road Property Management Company Limited | Households | 2011 |
| Lamb Catering and Events Limited | Hospitality | 2017 |
| Lambdatek Limited | Wholesale & retail | 2010 |
| Lambert Design and Build Limited | Construction | 2017 |
| Lamborough Hill Property Limited | Real estate | 2014 |
| Lambourn Construction & Civils Limited | Construction | 2006 |
| Lambourn Surfacing Oxon Limited | Administrative & support | 2010 |
| Lamburngeekie Ltd | Professional & scientific | 2005 |
| Lamburngeekie Trustees Limited | Administrative & support | 2026 |
| LAN Global Logistics Ltd. | Administrative & support | 2013 |
| Lanada and Haines Limited | Professional & scientific | 2021 |
| Land DON Stuart Place Oxford Limited | Extraterritorial | 2023 |
| Land Merchants Ltd | Real estate | 2023 |
| Landmark Trees Ltd | Agriculture & fishing | 1999 |
| Landtax LLP | | 2008 |
| Langdale Partners Ltd | Financial services | 2024 |
| Lanier Theological Education Foundation | Education | 2021 |
| Lanleya Limited | Real estate | 2006 |
| LAP Research | Health & social care | 2008 |
| Laplacian Limited | Professional & scientific | 2002 |
| Laptop Buddy Limited | Wholesale & retail | 2023 |
| Lapwing Ltd | Manufacturing | 2025 |
| Larkfields (NO.4) Management Company Limited | Households | 1992 |
| Larkfields Ltd | Professional & scientific | 2024 |
| Larkhill House Management Company Limited | Households | 2005 |
| Larksway Investments Limited | Financial services | 2007 |
| Larousse and Co Ltd | Professional & scientific | 2012 |
| Lartin Ltd | Professional & scientific | 2025 |
| Lasallian Projects | Education | 2018 |
| Lata Brothers Ltd | Hospitality | 2024 |
| Lata Brothers Transport Ltd | Administrative & support | 2025 |
| Lathbury Manor Ltd | Health & social care | 2025 |
| Latifi Property Ltd | Real estate | 2022 |
| Latus Therapeutics Limited | Professional & scientific | 2020 |
| Latuspet Limited | Wholesale & retail | 2021 |
| LAU Family Partnership LLP | | 2014 |
| Launa Corporations Limited | Real estate | 2015 |
| Laura Beswick Training and Consultancy Ltd | Professional & scientific | 2024 |
| Laura Johnson Oncoplastics Limited | Health & social care | 2017 |
| Lavender Lodgings Ltd | Real estate | 2022 |
| Lawbox Group Ltd | Professional & scientific | 2017 |
| Lawrence Architects Ltd | Professional & scientific | 2020 |
| Lawrence Baker Limited | Construction | 2004 |
| Lawson Fuses Limited | Manufacturing | 1938 |
| Lawtext Publishing Limited | Information & communication | 1996 |
| Lawton Lorne Limited | Real estate | 1998 |
| Layalyz Lounge Ltd | Hospitality | 2025 |
| LB BIO Ltd | Professional & scientific | 2024 |
| LBA Books Ltd | Information & communication | 2024 |
| LBM Medical Ltd | Health & social care | 2019 |
| Lbnks Limited | Professional & scientific | 2008 |
| LBS1 Trading Ltd | Transport & logistics | 2024 |
| LC Holdings (Oxford) Limited | Construction | 2018 |
| Lccd Groundworks Limited | Construction | 2012 |
| Lcdc Limited | Health & social care | 2022 |
| LCP: Lifespan Clinical Psychology Services Ltd | Health & social care | 2021 |
| LCT City Locker Ltd | Wholesale & retail | 2025 |
| LDC Sartorial Limited | Wholesale & retail | 2019 |
| Ldmh Consulting Ltd | Professional & scientific | 2023 |
| LE Soula Limited | Wholesale & retail | 2010 |
| Leach-Davies Properties Ltd | Real estate | 2022 |
| Lead & Allure Limited | Professional & scientific | 2025 |
| Lead Atlas Ltd | Professional & scientific | 2026 |
| Leadershape Global Limited | Professional & scientific | 1992 |
| Leagle Lawyers Limited | Professional & scientific | 2022 |
| Leagos Productions Ltd | Information & communication | 2024 |
| Leak Seeker Limited | Other services | 2018 |
| Lean Creative Marketing Services Limited | Information & communication | 2016 |
| Leaping Salmon Property Management Ltd | Hospitality | 2024 |
| Lear Associates Limited | Professional & scientific | 2003 |
| Learn Italy Ltd. | Administrative & support | 2001 |
| Learn With Grace Ltd | Education | 2020 |
| Learn-World.Io Limited | Education | 2019 |
| Learndatai Ltd | Education | 2026 |
| Lebanese Cuisine Ltd | Hospitality | 2020 |
| Lebanese Cusinie Cowley Ltd | Hospitality | 2024 |
| Lebanese Munch Ltd | Hospitality | 2025 |
| Leckford Enterprises Limited | Information & communication | 2025 |
| Lede Limited | Information & communication | 2002 |
| LEE Kendall Ltd | Professional & scientific | 2022 |
| Leeds Goods Limited | Wholesale & retail | 2023 |
| Leego Limited | Real estate | 2019 |
| Leelium Balloons Limited | Other services | 1996 |
| Leep Properties Ltd | Real estate | 2006 |
| Leeson Clinical Consultancy Limited | Professional & scientific | 2023 |
| Leewardcd Ltd | Health & social care | 2019 |
| Left Wall Media Ltd | Information & communication | 2025 |
| Legacy Events Group Ltd | Professional & scientific | 2018 |
| Legal and Consulting Ltd | Administrative & support | 2022 |
| Legal and Financial Translations Limited | Professional & scientific | 2016 |
| Legal Cashiers Direct Ltd | Professional & scientific | 2026 |