| Dblessings Limited | Real estate | 2024 |
| DBX Global Limited | Extraterritorial | 2012 |
| DBX Sports Limited | Extraterritorial | 2011 |
| DC Sportswear Ltd | Wholesale & retail | 2022 |
| DCA Polymer Technology Limited | Professional & scientific | 2019 |
| Dean Heeney Ltd | Construction | 2018 |
| Decorn Beds and Furniture Limited | Wholesale & retail | 2024 |
| Defaultroute Limited | Information & communication | 2012 |
| Defence Fasteners Limited | Extraterritorial | 2007 |
| Denis R. Jones Limited | Construction | 2003 |
| Denprep Limited | Education | 2026 |
| Denver Ventures Limited | Hospitality | 2018 |
| Derwen College | Education | 2013 |
| Derwen College Consulting Limited | Professional & scientific | 2022 |
| DES Evans (Steel Fabrication) Limited | Manufacturing | 1983 |
| Design and Planning Associates Limited | Professional & scientific | 2007 |
| Destination Fitness Co. Ltd | Wholesale & retail | 2018 |
| Devsoc Ltd | Wholesale & retail | 2019 |
| Dewi Williams Ltd | Professional & scientific | 2010 |
| Dewpoint Solutions Limited | Administrative & support | 2014 |
| DEX Projects Ltd | Professional & scientific | 2025 |
| Dexter Dwellings Ltd | Real estate | 2020 |
| DF Boxing Limited | Arts & recreation | 2023 |
| DG Instrumentation Ltd | Manufacturing | 2018 |
| DGM Countryside Services Limited | Agriculture & fishing | 2026 |
| DGM Group Oswestry Limited | Real estate | 2026 |
| DH & KH Holdings Limited | Financial services | 2020 |
| Dialogic Leadership Group Ltd | Professional & scientific | 2026 |
| Digga Rentals Limited | Professional & scientific | 2002 |
| Digital Advisory Bookkeeping Limited | Professional & scientific | 2025 |
| DIN Fasteners Ltd. | Manufacturing | 1992 |
| Discount Trade Supplies Ltd | Wholesale & retail | 2014 |
| Dispense 2 U Ltd | Health & social care | 2010 |
| Diva Nails Design Ltd | Other services | 2026 |
| DJ Construction (Shropshire) Limited | Construction | 2015 |
| DJ Inspection & Engineering Services Ltd | Manufacturing | 2021 |
| DJ Software Consultancy Limited | Information & communication | 1997 |
| DMK and NK Limited | Professional & scientific | 2020 |
| Dmpc Ltd | Information & communication | 2015 |
| DNE Electrical Limited | Construction | 2016 |
| DNT Group Limited | Water & waste | 2005 |
| Dona Wynne Davies Ltd | Professional & scientific | 2015 |
| Douze Restaurants Limited | Hospitality | 2021 |
| Dpas Investment and Consultancy Services Limited | Professional & scientific | 2011 |
| Dpas Limited | Health & social care | 1996 |
| Dragon Machinery Limited | Manufacturing | 2002 |
| Drcg Medical Ltd | Health & social care | 2022 |
| Dreamworks Marketing Limited | Professional & scientific | 2017 |
| Dreco Investments Limited | Professional & scientific | 2011 |
| Drew a Pretty Picture Ltd | Information & communication | 2012 |
| Driver Solutions Ltd | Administrative & support | 2026 |
| DRM (Lifts and Fabrication) Ltd | Manufacturing | 2011 |
| DRM Landscaping & Groundworks Limited | Construction | 2014 |
| Drtj Ltd | Hospitality | 2020 |
| DS Global Expediting Services Ltd | Mining & quarrying | 2015 |
| DSI Joinery and Electrical Ltd | Construction | 2026 |
| DSI Shopfitting Ltd | Construction | 2025 |
| Dssj Property Ltd | Real estate | 2026 |
| DTB Land & New Homes Limited | Real estate | 2004 |
| DTB Land Consultants Limited | Real estate | 2006 |
| DTS Media Ltd | Information & communication | 2017 |
| DW Dulson Topco Limited | Administrative & support | 2017 |
| DWR Property Development Ltd | Construction | 2020 |
| Dyfi Bike Park Limited | Arts & recreation | 2017 |
| Dyfi Timber Company Ltd | Manufacturing | 2008 |
| E a H Construction Ltd | Construction | 2013 |
| E C Hollywell Limited | Wholesale & retail | 2003 |
| E H Nutting Limited | Professional & scientific | 2017 |
| E. Richard Lloyd Ltd | Professional & scientific | 2011 |
| E5E4 Limited | Professional & scientific | 2022 |
| Early Explorers Shropshire Ltd | Health & social care | 2026 |
| Eble Professional Services Limited | Professional & scientific | 2014 |
| Ecofast Environmental UK Ltd | Wholesale & retail | 2019 |
| Ecofast Global Ltd | Manufacturing | 2025 |
| Ecostruct Limited | Construction | 1999 |
| Edwards and Jones Property Limited | Real estate | 2024 |
| Edwards Cladding Ltd | Construction | 2020 |
| Edwards Worx Ltd | Manufacturing | 2026 |
| Ejwpower Ltd | Professional & scientific | 2023 |
| Electric Horse Financial Services Limited | Financial services | 2026 |
| Electrogas.Uk Limited | Professional & scientific | 2014 |
| Elements Europe (S.E.) Limited | Construction | 2005 |
| Elevation Marketplace Services Limited | Wholesale & retail | 2020 |
| Elite Developments Shropshire Limited | Construction | 2017 |
| Elite Precast Concrete Limited | Manufacturing | 2007 |
| Elite Shropshire Homes Limited | Construction | 2025 |
| Elizabeth Darlington Art Ltd | Arts & recreation | 2023 |
| Ellis Meadow (Selattyn) Management Company Limited | Households | 2022 |
| Enclose Self Storage Limited | Real estate | 2026 |
| Enclose Storage Limited | Real estate | 2026 |
| Energy Channeling Electrical Contractors Ltd | Construction | 2003 |
| Energy Efficiency Association C.I.C. | Information & communication | 2017 |
| Engender (Whitchurch) Ltd | Real estate | 2023 |
| English Language Solutions Limited | Education | 2016 |
| Enova Energy UK Limited | Information & communication | 2026 |
| Enviroblast Shropshire Ltd | Administrative & support | 2015 |
| EP Therapies Ltd | Other services | 2018 |
| Equilibrium Management Solutions Limited | Professional & scientific | 2021 |
| Eratt Property Management Solutions Ltd | Real estate | 2013 |
| Ercall (ROL) Limited | Extraterritorial | 2020 |