| David John Clapham Ltd | Extraterritorial | 2022 |
| DB Recruitment Services Ltd | Administrative & support | 2020 |
| Dealerflow Ltd | Information & communication | 2026 |
| Dean Austerfield Flooring Ltd | Manufacturing | 2010 |
| Deans Fine Jewellery Limited | Wholesale & retail | 2001 |
| Deepsleep Beds UK Ltd | Manufacturing | 2009 |
| Denning Holdings Limited | Real estate | 2022 |
| Denning Investing Ltd | Financial services | 2023 |
| Densax Limited | Wholesale & retail | 2009 |
| Denton Hampshire International Ltd | Administrative & support | 2017 |
| Denykem Limited | Manufacturing | 1973 |
| Dependable Packaging Limited | Manufacturing | 2006 |
| DES Morrow Tail Lift Services Limited | Wholesale & retail | 1992 |
| Devapay Limited | Construction | 2025 |
| Dewsbury Cleaning Ltd | Administrative & support | 2026 |
| DF Construction Services Ltd | Professional & scientific | 2023 |
| DG Access Ltd | Mining & quarrying | 2014 |
| DGP Residential Limited | Real estate | 2024 |
| Diamond Project Services Ltd | Professional & scientific | 2020 |
| Diamond Social Care Ltd | Health & social care | 2023 |
| Direct Energy Efficiency Solution Limited | Construction | 2014 |
| Diva Nais 1A Ltd | Other services | 2023 |
| Djfm Investments Limited | Professional & scientific | 2018 |
| Djfm Limited | Professional & scientific | 2012 |
| DJL Sign Installations Ltd | Construction | 2018 |
| DJM Legal Ltd | Professional & scientific | 2015 |
| DM Property Rentals Ltd | Construction | 2025 |
| DMG Commercial Properties Ltd | Real estate | 2025 |
| Doerupper Ltd | Real estate | 2025 |
| Donald Schofield (Pontefract) Limited | Financial services | 2016 |
| Double Time Limited | Wholesale & retail | 2022 |
| Doug Booth (UK) Limited | Manufacturing | 2009 |
| DPJ Electrical Group Ltd | Construction | 2023 |
| DR Plastering Rendering & Partitions Ltd | Construction | 2010 |
| DRA Legal Ltd | Professional & scientific | 2013 |
| Dreamify Limited | Wholesale & retail | 2025 |
| Dredmax Ltd | Wholesale & retail | 2024 |
| Driffield Limited | Information & communication | 2016 |
| Driftgate Limited | Real estate | 2022 |
| Drowstan Limited | Manufacturing | 1979 |
| Drury Properties Ltd | Real estate | 2020 |
| Duct-Flex Installations Ltd | Construction | 2020 |
| DVR Properties Limited | Real estate | 2002 |
| DXE Ventures Ltd | Real estate | 2024 |
| E J Day Limited | Administrative & support | 2014 |
| E.M.L. Financial Services Limited | Financial services | 2003 |
| EA Digitalmarket Ltd | Wholesale & retail | 2025 |
| Edgerton Gears Limited | Manufacturing | 1994 |
| Edoru Limited | Information & communication | 2006 |
| Education Ossett - Community Trust | Education | 2008 |
| Edward Clay & SON Limited | Manufacturing | 1943 |
| Edwards Developments Ltd | Professional & scientific | 2020 |
| Efficient Water Management Limited | Extraterritorial | 2005 |
| Efhas Ltd | Health & social care | 2025 |
| EHG LLC Limited | Real estate | 2026 |
| ELC Commercials Limited | Wholesale & retail | 2026 |
| Elevated Landscaping Limited | Administrative & support | 2025 |
| Eleve Luxury Travel Ltd | Administrative & support | 2025 |
| Elmet Screencraft (Leeds) Limited | Manufacturing | 1989 |
| Elmtech Hvac FM Ltd | Water & waste | 2013 |
| Encirco Limited | Manufacturing | 2022 |
| Endav Limited | Other services | 2023 |
| Energex Eco Limited | Construction | 2025 |
| Enhance and Pamper Limited | Other services | 2019 |
| Enterprise Handling (UK) Limited | Administrative & support | 2011 |
| Epic Legacies Ltd | Financial services | 2014 |
| ES Local Ltd | Wholesale & retail | 2026 |
| Espoir Beds Ltd | Wholesale & retail | 2019 |
| Ettles Compliance Advice Ltd | Professional & scientific | 2025 |
| Evergreen Active CIC | Education | 2019 |
| Evolaze Laser Suite Ltd | Other services | 2025 |
| Exley & Co Limited | Professional & scientific | 2009 |
| Express Tyre & Auto Ltd | Wholesale & retail | 2011 |
| External Funding Matters Limited | Professional & scientific | 2000 |
| Extreme Comfort (UK) Limited | Wholesale & retail | 2005 |
| Extreme Motor Sales Ltd | Wholesale & retail | 2023 |
| Face the Future Holdings Limited | Financial services | 2019 |
| Face the Future Online Limited | Health & social care | 2014 |
| FAE Electrical Ltd | Professional & scientific | 2019 |
| Fairfield Activities CIC | Education | 2026 |
| Fairy Prints Ltd | Manufacturing | 2025 |
| Falcon Van Conversions Ltd | Manufacturing | 2021 |
| Farren Limited | Other services | 2026 |
| Farview Property Limited | Real estate | 2021 |
| Fazal Noor Group Ltd | Transport & logistics | 2023 |
| FC Burrow Limited | Construction | 2007 |
| FC Burrow Properties Limited | Construction | 1976 |
| FGC Albums Limited | Wholesale & retail | 2014 |
| Filey Sports Bar Limited | Hospitality | 2019 |
| Find My Car Franchise Ltd | Wholesale & retail | 2019 |
| Find My Car Wakefield Ltd | Wholesale & retail | 2023 |
| Finger Industries Limited | Information & communication | 2002 |
| Finn Leslie Racing Limited | Arts & recreation | 2025 |
| Finney Electrical Limited | Construction | 2016 |
| Fired UP Technologies Ltd | Wholesale & retail | 2011 |
| First Car Leasing Limited | Financial services | 2000 |
| Firth Services Limited | Professional & scientific | 2002 |
| Fleetyre Limited | Wholesale & retail | 2011 |
| Fletchers Rooflines Limited | Construction | 2012 |
| FLG Holdings Ltd | Households | 2025 |